Patents by Inventor Gregory Donovan

Gregory Donovan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND SYSTEMS FOR HIGH-THROUGHPUT BIOCHEMICAL SCREENS
    Publication number: 20250034551
    Abstract: Provided are high-throughput screens for biologically active modulators of a target enzyme that mimic or recreate natural processes of diversification and selection. In some embodiments, the platform comprises one or more expression systems including without limitation (i) a two-hybrid system that, when expressed in a cell, links survival of the cell to the modulation of a therapeutic target, and (ii) a metabolic system that enables the biosynthesis of structurally varied modulators of the therapeutic agent.
    Type: Application
    Filed: November 3, 2022
    Publication date: January 30, 2025
    Inventors: Nolan O'CONNOR, Andrew MARKLEY, Hannah EDSTROM, Jerome Michael FOX, Tommaso Antonio FODERARO, Ankur Kulshreshtha SARKAR, Matthew TRAYLOR, Levi Daniel KRAMER, Gregory DONOVAN
  • Method of cell inhibition using polypeptides derived from the venom of the Austrialian jumper ant Myrmecia pilosula
    Patent number: 6294649
    Abstract: An isolated polypeptide having cytotoxic activity comprising the amino acid sequence of Pilosulin 1 shown in the figure, and active portion thereof, or a functionally equivalent amino acid sequence thereof, and a method of inhibiting the growth of a cell comprising exposing the cell to an effective amount of Pilosulin 1 shown in the figure, and active portion thereof, or a functionally equivalent amino acid sequence thereof, such that the growth of the cell is inhibited.
    Type: Grant
    Filed: October 8, 1999
    Date of Patent: September 25, 2001
    Assignee: Northern Sydney Area Health Service
    Inventors: Gregory Donovan, Brian Baldo