Patents by Inventor Gregory E. Mirigian
Gregory E. Mirigian has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 7771369Abstract: Catheters such as guide catheters can be configured for delivery of devices to vasculature portions such as intracranial spaces while retaining a desired level of flexibility. A catheter having an elongate shaft can include removable support means that can provide column support to the elongate shaft. The elongate shaft can include anchoring means that releasably secure the removable support means. The catheter can be deployed within a patient's vasculature, followed by deploying the removable support means.Type: GrantFiled: December 5, 2003Date of Patent: August 10, 2010Assignee: Boston Scientific Scimed, Inc.Inventors: Stephen Griffin, Gregory E. Mirigian
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Publication number: 20090227983Abstract: A medical device including a shaft having an elongated inner member and an elongated tubular reinforcing member disposed over at least a portion of the inner member. In some embodiments, at least a portion of the outer surface of the inner member is spaced from the inner surface of the reinforcing member, defining a space substantially free of any other structures of the device. In some embodiments, the shaft can include a tip structure disposed on a distal portion of the inner member. In some such embodiments, the reinforcing member has a distal end, and the tip structure is disposed on the distal portion of the inner member adjacent the distal end of the reinforcing member. Additionally, in some embodiments, the reinforcing member can include a plurality of apertures defined therein, for example, to enhance the flexibility or other such characteristics of all or portions of the reinforcing member.Type: ApplicationFiled: May 21, 2009Publication date: September 10, 2009Applicant: BOSTON SCIENTIFIC SCIMED, INC.Inventors: STEPHEN GRIFFIN, ELAINE LIM, GREGORY E. MIRIGIAN
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Publication number: 20090177261Abstract: Disclosed herein are detachment mechanisms for vaso-occlusive devices that allow for rapid operator-controlled release of the vaso-occlusive device into the selected site. Also disclosed are vaso-occlusive assemblies comprising these detachment mechanisms and methods of using these detachment mechanisms and vaso-occlusive assemblies.Type: ApplicationFiled: January 5, 2009Publication date: July 9, 2009Inventors: Clifford Teoh, Michael Williams, Gregory E. Mirigian, Kirsten Carroll, James M. Anderson, Jay Rassat, Benjamin Arcand, Derek Sutermeister
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Patent number: 7540865Abstract: A medical device including a shaft having an elongated inner member and an elongated tubular reinforcing member disposed over at least a portion of the inner member. In some embodiments, at least a portion of the outer surface of the inner member is spaced from the inner surface of the reinforcing member, defining a space substantially free of any other structures of the device. In some embodiments, the shaft can include a tip structure disposed on a distal portion of the inner member. In some such embodiments, the reinforcing member has a distal end, and the tip structure is disposed on the distal portion of the inner member adjacent the distal end of the reinforcing member. Additionally, in some embodiments, the reinforcing member can include a plurality of apertures defined therein, for example, to enhance the flexibility or other such characteristics of all or portions of the reinforcing member.Type: GrantFiled: July 13, 2005Date of Patent: June 2, 2009Assignee: Boston Scientific Scimed, Inc.Inventors: Stephen Griffin, Elaine Lim, Gregory E. Mirigian
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Patent number: 7338511Abstract: A solid embolic material that is capable of filling irregularly shaped and asymmetrical vascular defects in a controlled and predictable manner, without the difficulties associated with delivery of the embolic material through a microcatheter and containment of the embolic material in a defect. A detachable embolic balloon with optional check valve for maintaining liquid in the balloon prior to curing and optional multi-leaflet covering to prevent the balloon from expanding into the native vascular lumen.Type: GrantFiled: May 24, 2002Date of Patent: March 4, 2008Assignee: Boston Scientific-Scimed, Inc.Inventors: Gregory E. Mirigian, Huey Quoc Chan, Thomas Yung-Hui Chien, Stephen C. Porter, Robert P. Eury
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Patent number: 7018346Abstract: A guide wire with a distal portion having adjustable flexibility. The guide wire may include a distal polymeric member and a heat source. The heat source may be activated to cause the polymeric member to increase in temperature and increase in flexibility. The increase in flexibility of the distal portion of the guide wire enhances the ability of the guide wire to navigate tortuous vasculature to a target site. After the guide wire has been navigated to the target site, the heat source may be deactivated to cause the polymeric member to decrease in temperature and increase in stiffness. The increase in stiffness of the distal portion of the guide wire enhances support provided for devices (e.g., catheters) advanced thereon.Type: GrantFiled: December 18, 2001Date of Patent: March 28, 2006Assignee: Scimed Life Systems, Inc.Inventors: Stephen Griffin, Gregory E. Mirigian
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Patent number: 7001369Abstract: An medical device include a shaft having an elongated inner tubular member and an elongated tubular reinforcing member disposed over a portion of the inner tubular member. In some embodiments, the reinforcing member is disposed about a proximal portion of the inner tubular member such that a distal portion of the inner tubular member is free of the reinforcing member. In some embodiments, the at least a portion of an outer surface of the inner tubular member is spaced from an inner surface of the reinforcing member. In some embodiments, the shaft can include a tip structure disposed on the distal portion of the inner tubular member. In some such embodiments, reinforcing member has a distal end, and the tip structure is disposed on the distal portion of the inner tubular member adjacent the distal end of the reinforcing member.Type: GrantFiled: March 27, 2003Date of Patent: February 21, 2006Assignee: SciMed Life Systems, Inc.Inventors: Stephen Griffin, Elaine Lim, Gregory E. Mirigian
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Publication number: 20040193140Abstract: An medical device include a shaft having an elongated inner tubular member and an elongated tubular reinforcing member disposed over a portion of the inner tubular member. In some embodiments, the reinforcing member is disposed about a proximal portion of the inner tubular member such that a distal portion of the inner tubular member is free of the reinforcing member. In some embodiments, the at least a portion of an outer surface of the inner tubular member is spaced from an inner surface of the reinforcing member. In some embodiments, the shaft can include a tip structure disposed on the distal portion of the inner tubular member. In some such embodiments, reinforcing member has a distal end, and the tip structure is disposed on the distal portion of the inner tubular member adjacent the distal end of the reinforcing member.Type: ApplicationFiled: March 27, 2003Publication date: September 30, 2004Applicant: SCIMED LIFE SYSTEMS,INC.Inventors: Stephen Griffin, Elaine Lim, Gregory E. Mirigian
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Patent number: 6682493Abstract: Alternative designs, materials and manufacturing methods for medical devices such as guidewires. Some embodiments are directed to a guidewire, including a core wire having a proximal portion and a distal portion, and an elongated distal assembly defining an inner lumen, the elongated distal assembly connected to the core wire adjacent the distal portion of the core wire, wherein the elongated distal assembly includes a plurality of separate and discrete interlocking segments. Some other embodiments are directed to a guidewire including a tubular segment connected to the distal portion of the corewire, wherein the tubular segment includes a plurality of notches therein to increase the lateral flexibility of the segment while maintaining rotational torqueability.Type: GrantFiled: December 3, 2001Date of Patent: January 27, 2004Assignee: SciMed Life Systems, Inc.Inventor: Gregory E. Mirigian
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Publication number: 20030220666Abstract: A solid embolic material that is capable of filling irregularly shaped and asymmetrical vascular defects in a controlled and predictable manner, without the difficulties associated with delivery of the embolic material through a microcatheter and containment of the embolic material in a defect. A detachable embolic balloon with optional check valve for maintaining liquid in the balloon prior to curing and optional multi-leaflet covering to prevent the balloon from expanding into the native vascular lumen.Type: ApplicationFiled: May 24, 2002Publication date: November 27, 2003Applicant: SciMed Life Systems, Inc.Inventors: Gregory E. Mirigian, Huey Quoc Chan, Thomas Yung-Hui Chien, Stephen C. Porter, Robert P. Eury
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Publication number: 20030114776Abstract: A guide wire with a distal portion having adjustable flexibility. The guide wire may include a distal polymeric member and a heat source. The heat source may be activated to cause the polymeric member to increase in temperature and increase in flexibility. The increase in flexibility of the distal portion of the guide wire enhances the ability of the guide wire to navigate tortuous vasculature to a target site. After the guide wire has been navigated to the target site, the heat source may be deactivated to cause the polymeric member to decrease in temperature and increase in stiffness. The increase in stiffness of the distal portion of the guide wire enhances support provided for devices (e.g., catheters) advanced thereon.Type: ApplicationFiled: December 18, 2001Publication date: June 19, 2003Applicant: SciMed Life Systems, Inc.Inventors: Stephen Griffin, Gregory E. Mirigian
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Publication number: 20030105415Abstract: Alternative designs, materials and manufacturing methods for medical devices such as guidewires. Some embodiments are directed to a guidewire, including a core wire having a proximal portion and a distal portion, and an elongated distal assembly defining an inner lumen, the elongated distal assembly connected to the core wire adjacent the distal portion of the core wire, wherein the elongated distal assembly includes a plurality of separate and discrete interlocking segments. Some other embodiments are directed to a guidewire including a tubular segment connected to the distal portion of the corewire, wherein the tubular segment includes a plurality of notches therein to increase the lateral flexibility of the segment while maintaining rotational torqueability.Type: ApplicationFiled: December 3, 2001Publication date: June 5, 2003Applicant: SciMed Life Systems, Inc.Inventor: Gregory E. Mirigian
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Publication number: 20020156459Abstract: The present invention relates generally to intravascular catheters for performing medical procedures. An intravascular catheter is disclosed comprising a multi-layered shaft having a shapable distal end. The shaft may comprise an inner liner; a second layer disposed over the inner liner, the second layer having a proximal segment and a distal segment corresponding to the shapable portion of the shaft; a third layer disposed over the second layer; and a fourth layer disposed over the third layer.Type: ApplicationFiled: August 31, 2001Publication date: October 24, 2002Applicant: SciMed Life Systems, IncInventors: Ting Tina Ye, Gregory E. Mirigian
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Patent number: 6001092Abstract: A vasoocclusive device in the form of a coil for placement in the vasculature of an animal to form thrombus in a selected site such as an aneurysm or AVM. The device involves a primary coil form having thrombogenic fibers placed on the coil in a specified fashion. The coil will pass through the lumen of a vascular catheter in the primary coil form and evolve into a convoluted or complex secondary form when ejected from the catheter's distal end. The fibers are attached to the coil and cooperate with the coil so that upon ejection from the catheter, the convoluted coil forms a shape in which the central region or secondary coil form center that contains the majority of these fibers.Type: GrantFiled: August 12, 1997Date of Patent: December 14, 1999Assignee: Target Therapeutics, Inc.Inventors: Gregory E. Mirigian, Nga Thi Van, Son M. Gia
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Patent number: 5769796Abstract: This is a composite guidewire for use in a catheter and is used for accessing a targeted site in a lumen system of a patient's body. The guidewire core or guidewire section may be of a stainless steel or a high elasticity metal alloy, preferably a Ni--Ti alloy, also preferably having specified physical parameters. The composite guidewire assembly is especially useful for accessing peripheral or soft tissue targets. Variations include multi-section guidewire assemblies having (at least) super-elastic distal portions and super-elastic braided reinforcements along the mid or distal sections. A variation of the inventive guidewire includes the coating of the wire with a tie layer and then with a one or more lubricious polymers to enhance its suitability for use within catheters and with the interior of vascular lumen.Type: GrantFiled: January 22, 1997Date of Patent: June 23, 1998Assignee: Target Therapeutics, Inc.Inventors: Thomas J. Palermo, Gene Samson, Gregory E. Mirigian, U. Hiram Chee, Erik T. Engelson, Edward Snyder
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Patent number: 5749837Abstract: This invention is a surgical device. It is a guidewire for use in a catheter and is used for accessing a targeted site in a lumen system of a patient's body. The guidewire or guidewire section may be of a stainless steel or a high elasticity metal alloy, preferably a Ni--Ti alloy, having specified physical parameters. The guidewire is especially useful for accessing peripheral or soft tissue targets. A special variation of the inventive guidewire includes the coating of the wire with a tie layer and then with a one or more lubricious polymers to enhance its suitability for use within catheters and with the interior of vascular lumen.Type: GrantFiled: August 1, 1996Date of Patent: May 12, 1998Assignee: Target Therapeutics, Inc.Inventors: Thomas J. Palermo, Gene Samson, Gregory E. Mirigian, U. Hiram Chee
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Patent number: 5700258Abstract: A vasoocclusive coil for placement in the vasculature of an animal to form thrombus in a selected site such as an aneurysm or AVM. The device involves a primary coil form having thrombogenic fibers placed on the coil in a specified fashion. The coil will pass through the lumen of a vascular catheter in the primary coil form and evolve into a convoluted or complex secondary form when ejected from the catheter's distal end. The fibers are attached to the coil and cooperate with the coil so that upon ejection from the catheter, the convoluted coil forms a shape in which the central region or secondary coil form center that contains the majority of these fibers.Type: GrantFiled: September 29, 1995Date of Patent: December 23, 1997Assignee: Target Therapeutics, Inc.Inventors: Gregory E. Mirigian, Nga Thi Van, Son M. Gia
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Patent number: 5639277Abstract: This is a surgical device that, in particular, is for forming a vasoocclusion or embolism. Typically, it is a helically wound coil in which the helix is wound in such a way as to have multiple axially offset, longitudinal or focal axes. Another important facet of the invention is the presence of small diameter secondary coil windings adjacent large diameter coil windings. The device is sufficiently flexible and small that it may be delivered to a site within the vasculature of the human body using a pusher and a catheter. The device is generally linear when within the catheter but relaxes to form the multi-focal form after delivery from the distal end of the catheter lumen. Various mechanical connections may also be used to discharge the inventive coil from its pusher. Similarly, the coil may be attached to a pusher using a sacrificial joint, which sacrificial joint is dissolved by imposition of a small voltage within the human body.Type: GrantFiled: September 29, 1995Date of Patent: June 17, 1997Assignee: Target Therapeutics, Inc.Inventors: Michael J. Mariant, Gregory E. Mirigian, Nga T. Van, Roberto L. Orellana, Christopher G. M. Ken
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Patent number: 5578074Abstract: A thermally activated occlusive implant delivery assembly is provided. The assembly includes an occlusive implant device and a pusher. The pusher has a distal section and a proximal section. The distal section includes a coupling portion which is shape memory material and exhibits different configurations depending on the coupling portion's temperature. The coupling portion interlockingly engages the implant when it is in one of the configurations and releases the implant from interlocking engagement therewith when in another one of the configurations. In operation, the assembly is introduced into the body of a mammal via a guide catheter suited for the particular lumen being navigated. When the implant is positioned at the desired site, the coupling portion of the pusher is thermally activated to effect the return of its original, pre-set configuration, which is originally formed to release the implant from interlocking engagement therewith.Type: GrantFiled: December 22, 1994Date of Patent: November 26, 1996Assignee: Target Therapeutics, Inc.Inventor: Gregory E. Mirigian
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Patent number: 5549624Abstract: This invention is a vasoocclusive device. It is placed in the vasculature of an animal to form thrombus in a selected site such as an aneurysm or AVM. The device uses a central coil having thrombogenic fibers placed on the coil in a specified fashion. The coil will pass through the lumen of a vascular catheter and form a convolution when ejected from the catheter's distal end. The fibers are attached to the coil and cooperate with the coil so that upon ejection from the catheter, the convoluted coil forms a shape in which the central region contains the majority of these fibers.Type: GrantFiled: June 24, 1994Date of Patent: August 27, 1996Assignee: Target Therapeutics, Inc.Inventors: Gregory E. Mirigian, Nga T. Van