Abstract: A barrier door system to control movement of persons through an opening in an interior space of an aircraft. The barrier door system having a frame with outer members that extend around a gap. A barrier door has a first panel and a second panel that are pivotally connected together with the barrier door pivotally connected to the frame. The barrier door is movable between a stowed position and a deployed position. The stowed position includes the first panel and the second panel folded together in an overlapping configuration and positioned in the gap in the frame and away from the opening. The deployed position includes the first panel and the second panel positioned away from the gap and extending across the opening.

Abstract: A barrier door system configured to be positioned at an opening within an interior of an aircraft. The barrier door system comprises a door that is movable between a stowed position away from the opening and a deployed position that extends across the opening. A lock is mounted to the door and configured to lock the door in the deployed position with the lock configured to be immediately movable from a locked position to an unlocked position from a forward side of the door and to delay moving from the locked position to the unlocked position from a rear side of the door.

Abstract: Biosynthetic melanin can capture fentanyl from aqueous environments. The captured fentanyl can be released by introducing the fentanyl-bound melanin to an acidic environment. In this way, fentanyl can capture melanin for subsequent detection/analysis, in addition to operating to remove fentanyl for decontamination.

Abstract: Described herein is a chemoenzymatic route to produce the small molecule sebacic acid from the renewable feedstock, e.g. vegetable oil. In one embodiment, this involves treating the a starting material such vegetable oil with KMnO4, sodium thiocyanate, and acid to obtain sebacic acid. Yield could be improved by pretreating the starting material with a lipase and then with a linoleic acid isomerase obtained from Propionibacterium acnes to obtain trans-10, cis-12 conjugated linoleic acid (CLA). The sebacic acid can be further processed with lipase and 1-butanol to obtain dibutyl sebacate.

Abstract: Enzyme cascade reactions, wherein the product of a first enzyme is the substrate of a second enzyme and so forth, were found to be enhanced by the presence of peptides. It is believed that the peptides operate by forming coacervates, which are membrane-less compartments where, in the case of coacervates formed by peptides, the liquid-liquid phase separation involves water as the continuous phase both inside and outside the coacervate.

Abstract: A rhodium-loaded porphyrin complex, comprising the porphyrin (meso-tri(4-sulfonatophenyl) mono(4-carboxyphenyl)porphine (C1S3TPP)) with coordinated with rhodium, effectively neutralizes the biological activity of naturally-occurring and synthetic opioids.

Abstract: Multi-enzyme systems attached to nanoparticles are effective to efficiently and controllably incorporate stable isotopes (such as deuterium) during the synthesis of small molecules. In one example, deuterium is incorporated into (+)-dihydrocarvide using a cascade involving the enzymes (a) pentaerythritol tetranitrate reductase (PETNR) and (b) flavin-dependent cyclohexanone monooxygenase triple variant F249A/F280A/F435A (CHMO3M).

Abstract: Provided herein is a delivery device and vaporizable formulations that provide users or patients with the ability to safely, reliably, and conveniently obtain a high-quality, therapeutic vapor comprising an ayahuasca-like substance. The delivery device includes a chamber coupled to a power unit capable of providing power to vaporize the formulations for consumption of the substance in a consistently desirable and safe manner. Further included are kits and methods of treating psychological disorders using the delivery device and vaporizable formulations provided herein.

Abstract: Provided herein is a delivery device and vaporizable formulations that provide users or patients with the ability to safely, reliably, and conveniently obtain a high-quality, therapeutic vapor comprising an ayahuasca-like substance. The delivery device includes a chamber coupled to a power unit capable of providing power to vaporize the formulations for consumption of the substance in a consistently desirable and safe manner. Further included are kits and methods of treating psychological disorders using the delivery device and vaporizable formulations provided herein.

Abstract: Provided herein is a delivery device and vaporizable formulations that provide users or patients with the ability to safely, reliably, and conveniently obtain a high-quality, therapeutic vapor comprising an ayahuasca-like substance. The delivery device includes a chamber coupled to a power unit capable of providing power to vaporize the formulations for consumption of the substance in a consistently desirable and safe manner. Further included are kits and methods of treating psychological disorders using the delivery device and vaporizable formulations provided herein.

Abstract: A rhodium-loaded porphyrin complex, comprising the porphyrin (meso-tri(4-sulfonatophenyl) mono(4-carboxyphenyl)porphine (C1S3TPP)) with coordinated with rhodium, effectively neutralizes the biological activity of naturally-occurring and synthetic opioids.

Abstract: Addition of nanoparticles to a cell-free transcription/translation system significantly enhanced the efficiency of the system.

Abstract: An audio/video stream recording, storage, and delivery system 10 utilizes an Internet-based browser connection. The system 10 includes recording software 20, storage memory 30, a code generator 40, and a user interface 50. Preferably, the recording software 20 is located on the host back end 60 where it processes and records audio and video material that originates from the user front end 70 and is streamed to the host back end. The storage memory 30, which is also located on the host back end 60, stores the recorded audio and video material. The user interface 50 to the system provides a user located at the user front end 70 with remote access to a virtual recording room. The user interface 50 further enables the user to record audio and video material streamed from the user front end 70 by activating the recording software 20 located on the host back end 60. This is accomplished without requiring recording functionality on the user front end 70.

Abstract: Cargo molecules carrying one or more phenylboronate moieties useful for cellular uptake of the cargo molecules. Phenylboronate can be ligated, crosslinked or otherwise bonded to the cargo molecules. Cargo molecules include peptides and proteins. The phenylboronate groups are optionally conjugated to the cargo molecule via linking moieties that can be selectively cleaved, such cleavable linkers can allow the phenylboronate groups to be removed from the cargo molecule after the boronated cargo molecule is introduced into the cell. The invention includes certain phenylboronates which are boronation reagents, certain boronated oligopeptides and certain boronated peptides and proteins. The invention also includes kits for enhancing cellular uptake of cargo molecules by boronation with one or more phenylboronates or boronated oligopeptides.

Abstract: Methods for enhancing cellular uptake of cargo molecules by boronating the cargo molecule, particularly with one or more phenylboronic acid groups. Cellular uptake includes at least partial uptake into the cytosol. Boronation includes ligating, crosslinking or otherwise bonding one or more phenylboronic acids substituted to contain a reactive group to a cargo molecule. Boronation also includes ligating, crosslinking or otherwise bonding a phenylboronated oligopeptide to a cargo molecule. The phenylboronate groups are optionally conjugated to the cargo molecule via linking moieties that can be selectively cleaved, such cleavable linkers can allow the phenylboronate groups to be removed from the cargo molecule after the boronated cargo molecule is introduced into the cell. The invention includes certain phenylboronates which are boronation reagents, certain boronated oligopeptides and certain boronated peptides and proteins.

Abstract: An improved disposable hydration pouch and method of delivery is disclosed herein. The hydration pouch may be manufactured from poly-ethylene or other high self-friction polymers that can be thermally sealed, which allows the pouch to be inexpensive to manufacture and disposable. The hydration pouch also includes a plurality of latitudinal thermally sealed baffles to provide improved lateral support and strength while holding liquids during use over existing poly-ethylene hydration pouches in the prior art. The disposable hydration pouch may be used by athletes, hikers, cyclists, travelers, and more as a portable hydration source.

Abstract: Methods for enhancing cellular uptake of cargo molecules by boronating the cargo molecule, particularly with one or more phenylboronic acid groups. Cellular uptake includes at least partial uptake into the cytosol. Boronation includes ligating, crosslinking or otherwise bonding one or more phenylboronic acids substituted to contain a reactive group to a cargo molecule. Boronation also includes ligating, crosslinking or otherwise bonding a phenylboronated oligopeptide to a cargo molecule. The phenylboronate groups are optionally conjugated to the cargo molecule via linking moieties that can be selectively cleaved, such cleavable linkers can allow the phenylboronate groups to be removed from the cargo molecule after the boronated cargo molecule is introduced into the cell. The invention includes certain phenylboronates which are boronation reagents, certain boronated oligopeptides and certain boronated peptides and proteins.

Abstract: An improved disposable hydration pouch and method of delivery is disclosed herein. The hydration pouch may be manufactured from poly-ethylene or other high self-friction polymers that can be thermally sealed, which allows the pouch to be inexpensive to manufacture and disposable. The hydration pouch also includes a plurality of latitudinal thermally sealed baffles to provide improved lateral support and strength while holding liquids during use over existing poly-ethylene hydration pouches in the prior art. The disposable hydration pouch may be used by athletes, hikers, cyclists, travellers, and more as a portable hydration source.

Abstract: An audio/video stream recording, storage, and delivery system 10 utilizes an Internet-based browser connection. The system 10 includes recording software 20, storage memory 30, a code generator 40, and a user interface 50. Preferably, the recording software 20 is located on the host back end 60 where it processes and records audio and video material that originates from the user front end 70 and is streamed to the host back end. The storage memory 30, which is also located on the host back end 60, stores the recorded audio and video material. The user interface 50 to the system provides a user located at the user front end 70 with remote access to a virtual recording room. The user interface 50 further enables the user to record audio and video material streamed from the user front end 70 by activating the recording software 20 located on the host back end 60. This is accomplished without requiring recording functionality on the user front end 70.