Patents by Inventor Gregory F. Chin

Gregory F. Chin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SARS-COV2 MAIN PROTEASE INHIBITORS
    Publication number: 20240116946
    Abstract: The present disclosure relates to compounds of Formula I: and pharmaceutically acceptable salts thereof, pharmaceutical compositions thereof, useful in the treatment of treating viral infections, for example, coronaviridae infections.
    Type: Application
    Filed: October 3, 2023
    Publication date: April 11, 2024
    Inventors: Stephen E. Ammann, Xinpei Cai, Eda Y. Canales, Weng K. Chang, Gregory F. Chin, Henok H. Kinfe, Scott E. Lazerwith, Jessica L. McKinley, Michael R. Mish, Devan Naduthambi, Jason K. Perry, Kevin X. Rodriguez, Scott D. Schroeder, Christopher J. Swank, Joshua J. Van Veldhuizen
  • CD73 COMPOUNDS
    Publication number: 20240116928
    Abstract: There is provided a compound of Formula (I): or a pharmaceutically acceptable salt thereof, or a pharmaceutical composition of wherein the various substituents are defined herein,
    Type: Application
    Filed: June 29, 2023
    Publication date: April 11, 2024
    Inventors: Mark J. Bartlett, Gregory F. Chin, Jennifer L. Cosman Ellis, Richard L. Mackman, Michael R. Mish
  • CD73 compounds
    Patent number: 11919869
    Abstract: Provided herein is A compound of Formula I: or a pharmaceutically acceptable salt thereof, wherein the various substituents are described herein.
    Type: Grant
    Filed: October 27, 2022
    Date of Patent: March 5, 2024
    Assignee: Gilead Sciences, Inc.
    Inventors: Mark J. Bartlett, Gregory F. Chin, Michael O. Clarke, Jennifer L Cosman, Deeba Ensan, Bindu Goyal, Stephen Ho, Richard L Mackman, Michael R. Mish, Dustin S. Siegel, Kyle C. Tamshen, Hai Yang
  • CD73 COMPOUNDS
    Publication number: 20240043427
    Abstract: The present disclosure provides pyrimidine dione compounds, and pharmaceutical compositions thereof, for treating cancer, including solid tumors. The compounds can be used alone or in combination with other anti-cancer agents.
    Type: Application
    Filed: April 29, 2021
    Publication date: February 8, 2024
    Inventors: Mark J. Bartlett, Gregory F. Chin, Michael O. Clarke, Jennifer L. Cosman, Deeba Ensan, Bindu Goyal, Stephen Ho, Hon C. Hui, Richard L. Mackman, Michael R. Mish, Scott D. Schroeder, Nathan D. Shapiro, Dustin S. Siegel, Doris T. Tang, Hai Yang
  • Antiviral compounds
    Patent number: 11767337
    Abstract: The present disclosure provides compounds for treating a variety of diseases, such as respiratory syncytial virus (RSV), HRV, hMPV, Ebola, Zika, West Nile, Dengue, and HCV.
    Type: Grant
    Filed: February 18, 2021
    Date of Patent: September 26, 2023
    Assignee: GILEAD SCIENCES, INC.
    Inventors: Gregory F. Chin, Byoung-Kwon Chun, Michael O. Clarke, Bindu Goyal, Hon C. Hui, Petr Jansa, Richard L. Mackman, Dustin S. Siegel, Hai Yang
  • ANTIVIRAL COMPOUNDS
    Publication number: 20230295201
    Abstract: The present disclosure provides compounds for treating a variety of diseases, such as respiratory syncytial virus (RSV), HRV, hMPV, ebola, Zika, West Nile, Dengue, and HCV.
    Type: Application
    Filed: February 21, 2023
    Publication date: September 21, 2023
    Inventors: Daniel H. Byun, Gregory F. Chin, Byoung-kwon Chun, Michael O. Clarke, Bindu Goyal, Hon C. Hui, Petr Jansa, Richard L. Mackman, Michael R. Mish, Dustin S. Siegel, David Sperandio, Hai Yang, Lijun Zhang
  • CD73 COMPOUNDS
    Publication number: 20230183189
    Abstract: Provided herein is A compound of Formula I: or a pharmaceutically acceptable salt thereof, wherein the various substituents are described herein.
    Type: Application
    Filed: October 27, 2022
    Publication date: June 15, 2023
    Inventors: Mark J. Bartlett, Gregory F. Chin, Michael O. Clarke, Jennifer L. Cosman, Deeba Ensan, Bindu Goyal, Stephen Ho, Richard L. Mackman, Michael R. Mish, Dustin S. Siegel, Kyle C. Tamshen, Hai Yang
  • CD73 COMPOUNDS
    Publication number: 20230039553
    Abstract: The present disclosure provides pyrimidine dione compounds, and pharmaceutical compositions thereof, for treating cancer, including solid tumors. The compounds can be used alone or in combination with other anti-cancer agents.
    Type: Application
    Filed: April 29, 2021
    Publication date: February 9, 2023
    Inventors: Mark J. Bartlett, Gregory F. Chin, Michael O. Clarke, Jennifer L. Cosman, Deeba Ensan, Bindu Goyal, Stephen Ho, Hon C. Hui, Richard L. Mackman, Michael R. Mish, Scott D. Schroeder, Nathan D. Shapiro, Dustin S. Siegel, Doris T. Tang, Hai Yang
  • ANTIVIRAL COMPOUNDS
    Publication number: 20220356196
    Abstract: The present disclosure provides compounds for treating a variety of diseases, such as respiratory syncytial virus (RSV), HRV, hMPV, ebola, Zika, West Nile, Dengue, and HCV.
    Type: Application
    Filed: February 16, 2021
    Publication date: November 10, 2022
    Inventors: Daniel H. Byun, Gregory F. Chin, Byoung-kwon Chun, Michael O. Clarke, Bindu Goyal, Hon C. Hui, Petr Jansa, Richard L. Mackman, Michael R. Mish, Dustin S. Siegel, David Sperandio, Hai Yang, Lijun Zhang
  • ANTIVIRAL COMPOUNDS
    Publication number: 20210292348
    Abstract: The present disclosure describes 4?-fluoromethyl nucleosides for treating viral infections, including Dengue.
    Type: Application
    Filed: February 17, 2021
    Publication date: September 23, 2021
    Inventors: Daniel H. Byun, Gregory F. Chin, Michael O. Clarke, Bindu Goyal, Petr Jansa, Richard L. Mackman, Michael R. Mish, Dustin S. Siegel
  • ANTIVIRAL COMPOUNDS
    Publication number: 20210284670
    Abstract: The present disclosure provides compounds for treating a variety of diseases, such as respiratory syncytial virus (RSV), HRV, hMPV, Ebola, Zika, West Nile, Dengue, and HCV.
    Type: Application
    Filed: February 18, 2021
    Publication date: September 16, 2021
    Inventors: Gregory F. Chin, Byoung-Kwon Chun, Michael O. Clarke, Bindu Goyal, Hon C. Hui, Petr Jansa, Richard L. Mackman, Dustin S. Siegel, Hai Yang
  • PROCESSES FOR PREPARING TOLL-LIKE RECEPTOR MODULATOR COMPOUNDS
    Publication number: 20210017170
    Abstract: The present disclosure provides methods for preparing (R)-2-((2-amino-7-fluoropyrido[3,2-d]pyrimidin-4-yl)amino)-2-methylhexan-1-ol or a salt thereof and related key intermediates.
    Type: Application
    Filed: June 25, 2020
    Publication date: January 21, 2021
    Inventors: Evangelos Aktoudianakis, Andrea Ambrosi, Sylvie M. Asselin, Florence J. Bachrach, Pavel R. Badalov, Gregory F. Chin, Stephen P. Lathrop, Willard Lew, Richard L. Mackman, Jeffrey E. Merit, Samuel E. Metobo, Michael R. Mish, Beau P. Pritchett, Hyung-Jung Pyun, Christopher S. Regens, Tiago Vieira, Xianghong Wang, Adam B. Weinstein, Todd A. Wenderski, Zehua Zheng