Patents by Inventor Gregory G. Brucker
Gregory G. Brucker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240252316Abstract: Embodiments of delivery systems, devices and methods for delivering a prosthetic heart valve device to a heart chamber for expanded implementation are disclosed. More specifically, methods, systems and devices are disclosed for delivering a self-expanding prosthetic mitral valve device to the left atrium, with no engagement of the left ventricle, the native mitral valve leaflets or the annular tissue downstream of the upper annular surface during delivery, and in some embodiments with no engagement of the ventricle, mitral valve leaflets and/or annular tissue located downstream of the upper annular surface by the delivered, positioned and expanded prosthetic mitral valve device.Type: ApplicationFiled: November 8, 2023Publication date: August 1, 2024Inventors: Jeffrey W. Chambers, Gregory G. Brucker, Joseph P. Higgins, Saravana B. Kumar, Jason S. Diedering, Karl A. Kabarowski, Robert J. Thatcher, James E. Flaherty, Jeffrey R. Stone
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Patent number: 11957577Abstract: Embodiments of delivery systems, devices and methods for delivering a prosthetic heart valve device to a heart chamber for expanded implementation are disclosed. More specifically, methods, systems and devices are disclosed for delivering a self-expanding prosthetic mitral valve device to the left atrium, with no engagement of the left ventricle, the native mitral valve leaflets or the annular tissue downstream of the upper annular surface during delivery, and in some embodiments with no engagement of the ventricle, mitral valve leaflets and/or annular tissue located downstream of the upper annular surface by the delivered, positioned and expanded prosthetic mitral valve device.Type: GrantFiled: March 31, 2020Date of Patent: April 16, 2024Assignee: 4C Medical Technologies, Inc.Inventors: Jeffrey W. Chambers, Gregory G. Brucker, Joseph P. Higgins, Saravana B. Kumar, Jason S. Diedering, Karl A. Kabarowski, Robert J. Thatcher, James E. Flaherty, Jeffrey R. Stone
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Patent number: 11744993Abstract: A deflection system for deflecting a body lumen that includes a deflection mechanism, wherein the deflection mechanism includes: a beam having a proximal end and a distal end, wherein the beam includes a neutral position and a deflected position, a pull wire coupled to the distal end of the beam, wherein the beam is configured to be placed in the deflected position when a tension force is applied to the pull wire, and wherein at least a portion of the pull wire is configured to move to a displacement distance away from the beam when the tension force is applied to the pull wire, and one or more constraint members operatively coupled to the beam, wherein each one of the one or more constraint members is configured to limit the displacement distance of the pull wire from the beam when the tension force is applied to the pull wire.Type: GrantFiled: July 18, 2022Date of Patent: September 5, 2023Assignee: Innovations in Medicine, LLCInventors: Gregory G. Brucker, Steven D. Savage
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Publication number: 20230020076Abstract: A deflection system for deflecting a body lumen that includes a deflection mechanism, wherein the deflection mechanism includes: a beam having a proximal end and a distal end, wherein the beam includes a neutral position and a deflected position, a pull wire coupled to the distal end of the beam, wherein the beam is configured to be placed in the deflected position when a tension force is applied to the pull wire, and wherein at least a portion of the pull wire is configured to move to a displacement distance away from the beam when the tension force is applied to the pull wire, and one or more constraint members operatively coupled to the beam, wherein each one of the one or more constraint members is configured to limit the displacement distance of the pull wire from the beam when the tension force is applied to the pull wire.Type: ApplicationFiled: July 18, 2022Publication date: January 19, 2023Inventors: Gregory G. Brucker, Steven D. Savage
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Patent number: 11504205Abstract: A positioning device configured for introduction within a body lumen. Some embodiments include a catheter shaft with a longitudinal axis; an expandable element coupled along a length of the shaft, the expandable element being substantially thin and flexible in an unexpanded state and exerting a gentle outward force in an expanded state; and a deflection mechanism located within the shaft, wherein the deflection mechanism is flexible when in a non-deflected state and wherein, in the deflected state, the deflection curves in a predetermined lateral direction such that the positioning device laterally deflects the body lumen. In some embodiments, the deflection is a lateral curve that moves the body lumen away from a surgical site, such as a cardiac ablation site.Type: GrantFiled: March 31, 2022Date of Patent: November 22, 2022Assignee: Innovations in Medicine, LLCInventors: Gregory G. Brucker, Steven D. Savage
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Publication number: 20220218433Abstract: A positioning device configured for introduction within a body lumen. Some embodiments include a catheter shaft with a longitudinal axis; an expandable element coupled along a length of the shaft, the expandable element being substantially thin and flexible in an unexpanded state and exerting a gentle outward force in an expanded state; and a deflection mechanism located within the shaft, wherein the deflection mechanism is flexible when in a non-deflected state and wherein, in the deflected state, the deflection curves in a predetermined lateral direction such that the positioning device laterally deflects the body lumen. In some embodiments, the deflection is a lateral curve that moves the body lumen away from a surgical site, such as a cardiac ablation site.Type: ApplicationFiled: March 31, 2022Publication date: July 14, 2022Inventors: Gregory G. Brucker, Steven D. Savage
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Patent number: 11298203Abstract: A positioning device configured for introduction within a body lumen. Some embodiments include a catheter shaft with a longitudinal axis; an expandable element coupled along a length of the shaft, the expandable element being substantially thin and flexible in an unexpanded state and exerting a gentle outward force in an expanded state; and a deflection mechanism located within the shaft, wherein the deflection mechanism is flexible when in a non-deflected state and wherein, in the deflected state, the deflection curves in a predetermined lateral direction such that the positioning device laterally deflects the body lumen. In some embodiments, the deflection is a lateral curve that moves the body lumen away from a surgical site, such as a cardiac ablation site.Type: GrantFiled: November 23, 2017Date of Patent: April 12, 2022Assignee: Innovations in Medicine, LLCInventors: Gregory G. Brucker, Steven D. Savage
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Publication number: 20200276013Abstract: Embodiments of delivery systems, devices and methods for delivering a prosthetic heart valve device to a heart chamber for expanded implementation are disclosed. More specifically, methods, systems and devices are disclosed for delivering a self-expanding prosthetic mitral valve device to the left atrium, with no engagement of the left ventricle, the native mitral valve leaflets or the annular tissue downstream of the upper annular surface during delivery, and in some embodiments with no engagement of the ventricle, mitral valve leaflets and/or annular tissue located downstream of the upper annular surface by the delivered, positioned and expanded prosthetic mitral valve device.Type: ApplicationFiled: May 18, 2020Publication date: September 3, 2020Inventors: Jeffrey W. Chambers, Gregory G. Brucker, Joseph P. Higgins, Saravana B. Kumar, Jason S. Diedering, Karl A. Kabarowski, Robert J. Thatcher, James E. Flaherty, Jeffrey R. Stone
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Publication number: 20200222179Abstract: Embodiments of delivery systems, devices and methods for delivering a prosthetic heart valve device to a heart chamber for expanded implementation are disclosed. More specifically, methods, systems and devices are disclosed for delivering a self-expanding prosthetic mitral valve device to the left atrium, with no engagement of the left ventricle, the native mitral valve leaflets or the annular tissue downstream of the upper annular surface during delivery, and in some embodiments with no engagement of the ventricle, mitral valve leaflets and/or annular tissue located downstream of the upper annular surface by the delivered, positioned and expanded prosthetic mitral valve device.Type: ApplicationFiled: March 31, 2020Publication date: July 16, 2020Inventors: Jeffrey W. Chambers, Gregory G. Brucker, Joseph P. Higgins, Saravana B. Kumar, Jason S. Diedering, Karl A. Kabarowski, Robert J. Thatcher, James E. Flaherty, Jeffrey R. Stone
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Patent number: 10653523Abstract: Embodiments of delivery systems, devices and methods for delivering a prosthetic heart valve device to a heart chamber for expanded implementation are disclosed. More specifically, methods, systems and devices are disclosed for delivering a self-expanding prosthetic mitral valve device to the left atrium, with no engagement of the left ventricle, the native mitral valve leaflets or the annular tissue downstream of the upper annular surface during delivery, and in some embodiments with no engagement of the ventricle, mitral valve leaflets and/or annular tissue located downstream of the upper annular surface by the delivered, positioned and expanded prosthetic mitral valve device.Type: GrantFiled: January 18, 2018Date of Patent: May 19, 2020Assignee: 4C Medical Technologies, Inc.Inventors: Jeffrey W. Chambers, Gregory G. Brucker, Joseph P. Higgins, Saravana B. Kumar, Jason S. Diedering, Karl A. Kabarowski, Robert J. Thatcher, James E. Flaherty, Jeffrey R. Stone
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Publication number: 20190314109Abstract: A positioning device configured for introduction within a body lumen. Some embodiments include a catheter shaft with a longitudinal axis; an expandable element coupled along a length of the shaft, the expandable element being substantially thin and flexible in an unexpanded state and exerting a gentle outward force in an expanded state; and a deflection mechanism located within the shaft, wherein the deflection mechanism is flexible when in a non-deflected state and wherein, in the deflected state, the deflection curves in a predetermined lateral direction such that the positioning device laterally deflects the body lumen. In some embodiments, the deflection is a lateral curve that moves the body lumen away from a surgical site, such as a cardiac ablation site.Type: ApplicationFiled: November 23, 2017Publication date: October 17, 2019Inventors: Gregory G. Brucker, Steven D. Savage
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Publication number: 20180325588Abstract: The present invention provides an irrigated ablation electrode that includes a plurality of high L/d interior fluid passageways and/or slit-shaped apertures to provide for a lower rate of fluid flow and a more uniform distribution of fluid over an exterior surface of the electrode and reduce propensity for aperture blockage. In some embodiments, the slit-shaped apertures have an aspect ratio of at least three, at least five, at least ten, or at least fifteen. Some embodiments include maintaining a pressure drop of at least 345 pascals between irrigation fluid inside the irrigated ablation electrode and fluid immediately outside the electrode when the irrigation fluid has a flow rate of no more than five milliliters per minute (5 ml/min). Some embodiments include a low-density insert with a plurality of fluid channels on its exterior surface to more efficiently cool the electrode and provide a faster thermal response.Type: ApplicationFiled: July 16, 2018Publication date: November 15, 2018Inventors: Gregory G. Brucker, Steven D. Savage
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Publication number: 20180200049Abstract: Embodiments of delivery systems, devices and methods for delivering a prosthetic heart valve device to a heart chamber for expanded implementation are disclosed. More specifically, methods, systems and devices are disclosed for delivering a self-expanding prosthetic mitral valve device to the left atrium, with no engagement of the left ventricle, the native mitral valve leaflets or the annular tissue downstream of the upper annular surface during delivery, and in some embodiments with no engagement of the ventricle, mitral valve leaflets and/or annular tissue located downstream of the upper annular surface by the delivered, positioned and expanded prosthetic mitral valve device.Type: ApplicationFiled: January 18, 2018Publication date: July 19, 2018Inventors: Jeffrey W. Chambers, Gregory G. Brucker, Joseph P. Higgins, Saravana B. Kumar, Jason S. Diedering, Karl A. Kabarowski, Robert J. Thatcher, James E. Flaherty, Jeffrey R. Stone
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Patent number: 10022183Abstract: The present invention provides an irrigated ablation electrode that includes a plurality of high L/d interior fluid passageways and/or slit-shaped apertures to provide for a lower rate of fluid flow and a more uniform distribution of fluid over an exterior surface of the electrode and reduce propensity for aperture blockage. In some embodiments, the slit-shaped apertures have an aspect ratio of at least three, at least five, at least ten, or at least fifteen. Some embodiments include maintaining a pressure drop of at least 345 pascals between irrigation fluid inside the irrigated ablation electrode and fluid immediately outside the electrode when the irrigation fluid has a flow rate of no more than five milliliters per minute (5 ml/min). Some embodiments include a low-density insert with a plurality of fluid channels on its exterior surface to more efficiently cool the electrode and provide a faster thermal response.Type: GrantFiled: April 1, 2015Date of Patent: July 17, 2018Assignee: Innovations in Medicine, LLCInventors: Gregory G. Brucker, Steven D. Savage
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Patent number: 9724497Abstract: Various methods for optimizing coating of medical devices, such as balloon catheters are disclosed. One method configures catheter balloon folds based on balloon diameter and volume. Other methods include using a specifically-sized protective sheath, using a vacuum, using pressure, pulling the balloon through a coating solution, using at least one spacer or a wick between at least one fold for metering a therapeutic coating into the folds of the balloon, placing an intermediate layer between the balloon and the therapeutic coating, placing a soluble film having a therapeutic agent around the catheter balloon or inside the folds, and any combination thereof. Balloon catheters and catheter balloons having a specific folding configuration, a specifically-sized protective sheath, an intermediate layer, or a soluble film are also disclosed.Type: GrantFiled: July 24, 2015Date of Patent: August 8, 2017Assignee: Bayer Intellectual Property GmbHInventors: Benjamin T. Ewing, Gregory G. Brucker, Scott A. Bednar, John R. Periard, Ashok A. Sharma, Steven D. Savage, Arthur E. Uber, Brian P. Dickerson
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Publication number: 20170027460Abstract: An intraluminal microneurography probe has a probe body that is configured to be introduced into an artery near an organ of a body without preventing the flow of blood through the artery. An expandable sense electrode and an expandable stimulation electrode are fixed to the probe body at one end of each electrode such that movement of the other end toward the fixed end causes the sense electrode to expand from the probe body toward a wall of the artery. A ground electrode is configured to couple to the body, and a plurality of electrical connections are operable to electrically couple the electrodes to electrical circuitry. The sense electrode is operable to measure sympathetic nerve activity in response to excitation of the stimulation electrode. An ablation element is located between the expandable sense electrode and expandable stimulation electrode, and is operable to ablate nerves proximate to the artery.Type: ApplicationFiled: July 7, 2016Publication date: February 2, 2017Inventors: Jin Shimada, Harry A. Puryear, Gregory G. Brucker
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Publication number: 20160338773Abstract: Method and systems for ablating nerves including measurement of physiological parameters and/or electrical conduction. The method may include ablating nerves within an artery of a patient such as the renal artery and may include advancing a catheter into the artery, measuring a physiological parameter, emitting an electrical pulse into a wall of the artery, measuring the physiological parameter during or after the step of emitting the electrical pulse, ablating the artery wall, then repeating the steps of measuring the physiological parameter, emitting an electrical pulse, and measuring the physiological parameter during or after the step of emitting the electrical pulse. The change in the physiological parameter caused by the electrical pulse before ablation may be compared to the change in the physiological parameter caused by the electrical pulse after ablation to determine the degree of nerve ablation achieved and whether or not to perform further ablation.Type: ApplicationFiled: August 3, 2016Publication date: November 24, 2016Inventors: Jin Shimada, Gregory G. Brucker, William J. Rissmann
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Publication number: 20160287270Abstract: The present invention provides an aortic valvuloplasty catheter which, in one preferred embodiment, has a tapered distal balloon segment that anchors within the left ventricle outflow track of the patient's heart and a rounded proximal segment which conforms to the aortic sinuses forcing the valve leaflets open. In addition, this embodiment of the valvuloplasty catheter includes a fiber-based balloon membrane, a distal pigtail end hole catheter tip, and a catheter sheath.Type: ApplicationFiled: June 15, 2016Publication date: October 6, 2016Applicant: InterValve, Inc.Inventors: Wesley Pedersen, Robert A. Van Tassel, Robert S. Schwartz, Gregory G. Brucker, Skott E. Greenhalgh
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Patent number: 9439598Abstract: Method and systems for ablating nerves including measurement of physiological parameters and/or electrical conduction. The method may include ablating nerves within an artery of a patient such as the renal artery and may include advancing a catheter into the artery, measuring a physiological parameter, emitting an electrical pulse into a wall of the artery, measuring the physiological parameter during or after the step of emitting the electrical pulse, ablating the artery wall, then repeating the steps of measuring the physiological parameter, emitting an electrical pulse, and measuring the physiological parameter during or after the step of emitting the electrical pulse. The change in the physiological parameter caused by the electrical pulse before ablation may be compared to the change in the physiological parameter caused by the electrical pulse after ablation to determine the degree of nerve ablation achieved and whether or not to perform further ablation.Type: GrantFiled: March 12, 2013Date of Patent: September 13, 2016Assignee: NeuroMedic, Inc.Inventors: Jin Shimada, Gregory G. Brucker, William J. Rissmann
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Patent number: 9375555Abstract: The present invention provides an aortic valvuloplasty catheter which, in one preferred embodiment, has a tapered distal balloon segment that anchors within the left ventricle outflow track of the patient's heart and a rounded proximal segment which conforms to the aortic sinuses forcing the valve leaflets open. In addition, this embodiment of the valvuloplasty catheter includes a fiber-based balloon membrane, a distal pigtail end hole catheter tip, and a catheter sheath.Type: GrantFiled: June 25, 2013Date of Patent: June 28, 2016Assignee: InterValve, Inc.Inventors: Wesley Pedersen, Robert A. Van Tassel, Robert S. Schwartz, Gregory G. Brucker, Skott E. Greenhalgh