Patents by Inventor Gregory H. Altman

Gregory H. Altman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Multi-dimensional strain bioreactor
    Publication number: 20040219659
    Abstract: The invention features a bioreactor system. The system includes components, which exert physiologically relevant translational and rotational strains on a growing bioengineered tissue.
    Type: Application
    Filed: April 22, 2003
    Publication date: November 4, 2004
    Inventors: Gregory H. Altman, Gordana Vunjak-Novakovic, Peter R. H. Stark
  • Matrix for the production of tissue engineered ligaments, tendons and other tissue
    Publication number: 20030100108
    Abstract: The present invention provides a novel silk-fiber-based matrix having a wire-rope geometry for use in producing a ligament or tendon, particularly an anterior cruciate ligament, ex vivo for implantation into a recipient in need thereof. The invention further provides the novel silk-fiber-based matrix which is seeded with pluripotent cells that proliferate and differentiate on the matrix to form a ligament or tendon ex vivo. Also disclosed is a bioengineered ligament comprising the silk-fiber-based matrix seeded with pluripotent cells that proliferate and differentiate on the matrix to form the ligament or tendon. A method for producing a ligament or tendon ex vivo comprising the novel silk-fiber-based matrix is also disclosed.
    Type: Application
    Filed: November 16, 2001
    Publication date: May 29, 2003
    Inventors: Gregory H. Altman, David L. Kaplan, Rebecca L. Horan