Patents by Inventor Gregory Hageman

Gregory Hageman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HTRA1 MODULATION FOR TREATMENT OF AMD
    Publication number: 20230165976
    Abstract: The invention provides compositions and methods for treatment of Chromosome 10-driven age-related macular degeneration, including gene therapy to increase HTRA1 expression in retinal pigmented epithelial cells in the eye.
    Type: Application
    Filed: April 10, 2020
    Publication date: June 1, 2023
    Inventors: Brandi Williams, Gregory Hageman, Burt Timothy Richards, Osama Youssef
  • METHODS OF DIAGNOSING AND TREATING VASCULAR ASSOCIATED MACULOPATHY AND SYMPTOMS THEREOF
    Publication number: 20210353712
    Abstract: Disclosed herein are methods and compositions for the diagnosis and treatment of Vascular Associated Maculopathy, or a symptom thereof, in a subject. Disclosed herein are methods and compositions for the diagnosis and treatment of one or more symptoms associated with Vascular Associated Maculopathy Disclosed in a subject. Disclosed herein are methods and compositions for the diagnosis and treatment of severe maculopathy or late stage maculopathy in a subject. Disclosed herein are methods and compositions for the diagnosis and treatment of resolving aberrant choriocapillaris lobules in a subject.
    Type: Application
    Filed: March 2, 2020
    Publication date: November 18, 2021
    Inventors: Gregory Hageman, Yingbin Fu
  • METHODS OF PREDICTING THE DEVELOPMENT OF AMD BASED ON CHROMOSOME 1 AND CHROMOSOME10
    Publication number: 20210180129
    Abstract: Disclosed herein are methods and compositions for the diagnosis and treatment of AMD based on SNPs, haplotypes, and diplotypes on chromosome 1 and chromosome 10.
    Type: Application
    Filed: June 25, 2020
    Publication date: June 17, 2021
    Inventors: Gregory Hageman, Christian Matthew Pappas
  • METHODS OF PREDICTING THE DEVELOPMENT OF AMD BASED ON CHROMOSOME 1 AND CHROMOSOME 10
    Publication number: 20150211065
    Abstract: Disclosed herein are methods and compositions for the diagnosis and treatment of AMD based on SNPs, haplotypes, and diplotypes on chromosome 1 and chromosome 10.
    Type: Application
    Filed: September 13, 2013
    Publication date: July 30, 2015
    Inventors: Gregory Hageman, Christian Matthew Pappas
  • METHODS OF DIAGNOSING AND TREATING VASCULAR ASSOCIATED MACULOPATHY AND SYMPTOMS THEREOF
    Publication number: 20140323413
    Abstract: Disclosed herein are methods and compositions for the diagnosis and treatment of Vascular Associated Maculopathy, or a symptom thereof, in a subject. Disclosed herein are methods and compositions for the diagnosis and treatment of one or more symptoms associated with Vascular Associated Maculopathy Disclosed in a subject. Disclosed herein are methods and compositions for the diagnosis and treatment of severe maculopathy or last stage maculopathy in a subject. Disclosed herein are methods and compositions for the diagnosis and treatment of resolving aberrant choriocapillaris lobules in a subject.
    Type: Application
    Filed: March 15, 2012
    Publication date: October 30, 2014
    Applicant: UNIVERSITY OF UTAH RESEARCH FOUNDATION
    Inventors: Gregory Hageman, Yingbin Fu
  • Diagnostics and therapeutics for ocular disorders
    Publication number: 20070274921
    Abstract: The invention relates to methods for treating, preventing and diagnosing drusen-associated disorders.
    Type: Application
    Filed: July 13, 2007
    Publication date: November 29, 2007
    Applicant: Iowa Centers for Enterprise
    Inventors: Gregory Hageman, Robert Mullins
  • Methods and reagents for treatment and diagnosis of age-related macular degeneration
    Publication number: 20070020647
    Abstract: The invention relates to Factor H gene polymorphisms and haplotypes associated with an elevated or a reduced risk of AMD. The invention provides methods and reagents for diagnosis and treatment of AMD.
    Type: Application
    Filed: February 14, 2006
    Publication date: January 25, 2007
    Applicant: University of Iowa Research Foundation
    Inventors: Gregory Hageman, Richard Smith
  • Diagnostics and therapeutics for macular degeneration-related disorders
    Publication number: 20060263819
    Abstract: The invention relates to methods for treating, preventing and diagnosing macular degeneration-related disorders.
    Type: Application
    Filed: May 30, 2006
    Publication date: November 23, 2006
    Applicant: University of Iowa Research Foundation
    Inventors: Gregory Hageman, Robert Mullins
  • Diagnostics and therapeutics for macular degeneration-related disorders
    Publication number: 20050287601
    Abstract: The invention relates to methods for diagnosing and treating macular degeneration-related disorders. The invention also related to methods for identifying genes that cause macular degeneration-related disorders.
    Type: Application
    Filed: August 16, 2005
    Publication date: December 29, 2005
    Applicant: University of Iowa Research Foundation
    Inventors: Gregory Hageman, Robert Mullins
  • Diagnostics and therapeutics for arterial wall disruptive disorders
    Publication number: 20050119536
    Abstract: The invention provides diagnostics, therapeutics and drug screening assays for arterial wall disruptive disorders, based on the discovery of a high level of correlation between the incidence of arterial wall disruptive disorders and the incidence of Age Related Macular Degeneration (AMD). In one embodiment, the arterial wall disruptive disorder is an aortic aneurysm.
    Type: Application
    Filed: December 23, 2004
    Publication date: June 2, 2005
    Applicant: University of Iowa Research Foundation
    Inventor: Gregory Hageman