Patents by Inventor Gregory Haley

Gregory Haley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20080032999
    Abstract: The invention is directed to 5-amino-3-(3?-deoxy-?-D-ribofuranosyl)-thiazolo[4,5-d]pyrimidin-2,7-dione prodrugs, whose metabolized parent compound has immunomodulatory activity. The invention also relates to the therapeutic use of such prodrugs and pharmaceutical compositions thereof in treating disease states associated with abnormal cell growth, such as cancer.
    Type: Application
    Filed: June 21, 2007
    Publication date: February 7, 2008
    Applicant: Anadys Pharmaceuticals, Inc.
    Inventors: Gregory Haley, Joseph Lennox, Alan Xiang, Stephen Webber
  • Publication number: 20080020989
    Abstract: The invention is directed to carbonate and carbamate prodrugs of thiazolo[4,5-d]pyrimidine compounds, whose metabolized parent compound has immunomodulatory activity. The invention also relates to the therapeutic use of such prodrugs and pharmaceutical compositions thereof in treating disease states associated with abnormal cell growth, such as cancer.
    Type: Application
    Filed: July 17, 2007
    Publication date: January 24, 2008
    Applicant: Anadys Pharmaceuticals, Inc.
    Inventors: Gregory Haley, Joseph Lennox, Alan Xiang, Stephen Webber
  • Publication number: 20070167437
    Abstract: There are provided compounds of the formula I wherein R, V1, V2 and Ring A are described herein. The compounds exhibit anticancer activity.
    Type: Application
    Filed: January 17, 2007
    Publication date: July 19, 2007
    Inventors: Nader Fotouhi, Gregory Haley, Klaus Simonsen, Binh Vu, Stephen Webber
  • Publication number: 20060211693
    Abstract: There are presented compounds of the formula or pharmaceutically acceptable salts thereof, wherein Y1, Y2, X1, X2, X3 and R are as described in this application. These compounds are believed to inhibit MDM2-p53 interaction and as such the compounds will have anti-hyperproliferative cellular activity.
    Type: Application
    Filed: March 13, 2006
    Publication date: September 21, 2006
    Inventors: Nader Fotouhi, Gregory Haley, Klaus Simonsen, Binh Vu, Stephen Webber
  • Publication number: 20060167264
    Abstract: The present invention describes novel pyridine-3-sullonyl compounds having the formula (I) wherein R1, R2, R3, R4 and R5 are as defined herein. The present invention is also directed lo pesticidal compositions that include a) compounds of formula (11) wherein R1, R2, R3, R4 and R6 are as defined herein and b) a carrier. Moreover, the present invention relates to methods for protecting crops from insect attack by contacting the crop with a pesticidally effective amount of the compound of formula (II). In addition, the present invention includes methods for controlling insects by treating the target species with a pesticidally effective amount of the compound of formula (II).
    Type: Application
    Filed: November 22, 2002
    Publication date: July 27, 2006
    Inventors: Gregory Haley, Deborah Culbertson, Michael Treacy
  • Publication number: 20060160830
    Abstract: The invention is directed to 3,5-disubstituted and 3,5,7-trisubstituted-3H-oxazolo and 3H-thiazolo[4,5-d]pyrimidin-2-one compounds and prodrugs thereof that have immunomodulatory activity. The invention is also directed to the therapeutic or prophylactic use of such compounds and pharmaceutical compositions containing them, and to methods of treating diseases and disorders described herein, by administering effective amounts of such compounds and prodrugs.
    Type: Application
    Filed: December 16, 2005
    Publication date: July 20, 2006
    Applicant: Anadys Pharmaceuticals, Inc.
    Inventors: Stephen Webber, Gregory Haley, Joseph Lennox, Alan Xiang, Erik Rueden
  • Publication number: 20050288287
    Abstract: and the pharmaceutically acceptable salts and esters thereof, wherein X1, X2, X3, Y1, Y2 and R are described herein inhibit the interaction of MDM2 protein with a p53-like peptide and hence have anti proliferative activity.
    Type: Application
    Filed: May 13, 2005
    Publication date: December 29, 2005
    Inventors: Nader Fotouhi, Gregory Haley, Klaus Simonsen, Binh Vu, Stephen Webber
  • Publication number: 20050282803
    Abstract: The present invention relates to compounds of the formula and the pharmaceutically acceptable salts and esters thereof, a process for their manufacture, medicaments containing them as well as the use of these compounds as pharmaceutically active agents. The compounds show antiproliferative activity and may be especially useful for the treatment of cancer.
    Type: Application
    Filed: June 2, 2005
    Publication date: December 22, 2005
    Inventors: Gregory Haley, Norman Kong, Emily Liu, Binh Vu
  • Patent number: 6786153
    Abstract: A printing device, system and method are disclosed for measuring and displaying the amount of wear experienced by printing rolls. A wear detection mechanism is employed in connection with rolls, such as anilox-type rolls that transfer ink to a substrate in forming a printed image. A wear detection mechanism is engraved, etched, or the like into the outer circumferential surface of the roll to provide an indication of the amount of wear experienced by the roll. Portions provided in series at predetermined depths may be correlated with a depletion scale indicia to display the wear condition of a particular roll in a printing system. A depletable wear strip comprising multiple engraved portions which correlate with values upon a depletion scale may be employed.
    Type: Grant
    Filed: September 19, 2002
    Date of Patent: September 7, 2004
    Assignee: Interflex Laser Engravers, LLC
    Inventors: William Burrow, Gregory Haley
  • Publication number: 20040055489
    Abstract: A printing device, system and method are disclosed for measuring and displaying the amount of wear experienced by printing rolls. A wear detection mechanism is employed in connection with rolls, such as anilox-type rolls that transfer ink to a substrate in forming a printed image. A wear detection mechanism is engraved, etched, or the like into the outer circumferential surface of the roll to provide an indication of the amount of wear experienced by the roll. Portions provided in series at predetermined depths may be correlated with a depletion scale indicia to display the wear condition of a particular roll in a printing system. A depletable wear strip comprising multiple engraved portions which correlate with values upon a depletion scale may be employed.
    Type: Application
    Filed: September 19, 2002
    Publication date: March 25, 2004
    Inventors: William Burrow, Gregory Haley