Patents by Inventor Gregory Hamilton

Gregory Hamilton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BICYCLIC KETONE COMPOUNDS AND METHODS OF USE THEREOF
    Publication number: 20250282788
    Abstract: Some embodiments of the invention provide compounds having the general formula I: wherein R1, R2, R3a and R3b are as described herein, pharmaceutical compositions including the compounds, and methods of using the compounds.
    Type: Application
    Filed: May 23, 2025
    Publication date: September 11, 2025
    Applicant: Genentech, Inc.
    Inventors: Snahel PATEL, Gregory HAMILTON, Guiling ZHAO, Huifen CHEN, Blake DANIELS, Craig STIVALA
  • Bicyclic ketone compounds and methods of use thereof
    Patent number: 12344612
    Abstract: Some embodiments of the invention provide compounds having the general formula I: wherein R1, R2, R3a and R3b are as described herein, pharmaceutical compositions including the compounds, and methods of using the compounds.
    Type: Grant
    Filed: July 8, 2021
    Date of Patent: July 1, 2025
    Assignee: Genentech, Inc.
    Inventors: Snahel Patel, Gregory Hamilton, Guiling Zhao, Huifen Chen, Blake Daniels, Craig Stivala
  • Bicyclic sulfones and sulfoxides and methods of use thereof
    Patent number: 12338241
    Abstract: The invention provides novel compounds having the general formula I: wherein R1, RB1, RB2, n, p, q, the A ring and the B ring are as described herein, pharmaceutical compositions including the compounds, and methods of using the compounds.
    Type: Grant
    Filed: June 6, 2021
    Date of Patent: June 24, 2025
    Assignee: Genentech, Inc.
    Inventors: Snahel Patel, Gregory Hamilton, Craig Stivala, Huifen Chen, Blake Daniels
  • Bicyclic lactams and methods of use thereof
    Patent number: 12281101
    Abstract: The invention provides novel compounds having the general formula I: wherein R1, X, Z1, L, n, the A ring, the B ring, and the C ring are as described herein, pharmaceutical compositions including the compounds and methods of using the compounds.
    Type: Grant
    Filed: March 10, 2021
    Date of Patent: April 22, 2025
    Assignee: Genentech, Inc.
    Inventors: Snahel Patel, Gregory Hamilton, Craig Stivala, Huifen Chen, Guiling Zhao
  • BICYCLIC KETONE COMPOUNDS AND METHODS OF USE THEREOF
    Publication number: 20240300974
    Abstract: The invention provides novel compounds having the general formula I: wherein R1, the A ring and the B ring are as described herein, pharmaceutical compositions including the compounds, and methods of using the compounds.
    Type: Application
    Filed: November 21, 2023
    Publication date: September 12, 2024
    Applicant: Genentech, Inc.
    Inventors: Snahel PATEL, Gregory HAMILTON, Guiling ZHAO, Huifen CHEN, Blake DANIELS, Craig STIVALA
  • Bicyclic ketone compounds and methods of use thereof
    Patent number: 11834461
    Abstract: The invention provides novel compounds having the general formula I: wherein R1, the A ring and the B ring are as described herein, pharmaceutical compositions including the compounds, and methods of using the compounds.
    Type: Grant
    Filed: January 12, 2021
    Date of Patent: December 5, 2023
    Assignee: Genentech, Inc.
    Inventors: Snahel Patel, Gregory Hamilton, Guiling Zhao, Huifen Chen, Blake Daniels, Craig Stivala
  • Therapeutic compounds, compositions and methods of use thereof
    Patent number: 11731943
    Abstract: Compounds of Formula (I): and salts thereof, and methods of use as Janus kinase inhibitors are described herein.
    Type: Grant
    Filed: February 17, 2021
    Date of Patent: August 22, 2023
    Assignee: Genentech, Inc.
    Inventors: James John Crawford, Mark Zak, Terry Kellar, Yun-Xing Cheng, Wei Li, F. Anthony Romero, Paul Gibbons, Guiling Zhao, Gregory Hamilton, Simon Charles Goodacre
  • Bicyclic compounds for use as RIP1 kinase inhibitors
    Patent number: 11673892
    Abstract: The invention provides novel compounds having the general formula I: or pharmaceutically acceptable salts thereof, wherein RA, RB1, RB2, the A ring and the B ring are as described herein, pharmaceutical compositions including the compounds, and methods of using the compounds.
    Type: Grant
    Filed: April 9, 2020
    Date of Patent: June 13, 2023
    Assignee: Genentech, Inc.
    Inventors: Huifen Chen, Gregory Hamilton, Snahel Patel, Guiling Zhao, Blake Daniels, Craig Stivala
  • Bicyclic amide compounds and methods of use thereof
    Patent number: 11607396
    Abstract: The invention provides novel compounds having the general formula I: wherein R1, R2, the A ring and the B ring are as described herein, pharmaceutical compositions including the compounds and methods of using the compounds.
    Type: Grant
    Filed: January 4, 2021
    Date of Patent: March 21, 2023
    Assignee: Genentech, Inc.
    Inventors: Snahel Patel, Gregory Hamilton, Guiling Zhao, Huifen Chen
  • BICYCLIC SULFONES AND SULFOXIDES AND METHODS OF USE THEREOF
    Publication number: 20230002391
    Abstract: The invention provides novel compounds having the general formula I: wherein R1, RB1, RB2, n, p, q, the A ring and the B ring are as described herein, pharmaceutical compositions including the compounds, and methods of using the compounds.
    Type: Application
    Filed: June 6, 2021
    Publication date: January 5, 2023
    Applicant: Genentech, Inc.
    Inventors: Snahel Patel, Gregory Hamilton, Craig Stivala, Huifen Chen, Blake Daniels
  • BICYCLIC LACTAMS AND METHODS OF USE THEREOF
    Publication number: 20220348559
    Abstract: The invention provides novel compounds having the general formula I: wherein R1, X, Z1, L, n, the A ring, the B ring, and the C ring are as described herein, pharmaceutical compositions including the compounds and methods of using the compounds.
    Type: Application
    Filed: March 10, 2021
    Publication date: November 3, 2022
    Applicant: Genentech, Inc.
    Inventors: Snahel PATEL, Gregory HAMILTON, Craig STIVALA, Huifen CHEN, Guiling ZHAO
  • BICYCLIC AMIDE COMPOUNDS AND METHODS OF USE THEREOF
    Publication number: 20220339129
    Abstract: The invention provides novel compounds having the general formula I: wherein R1, R2, the A ring and the B ring are as described herein, pharmaceutical compositions including the compounds and methods of using the compounds.
    Type: Application
    Filed: January 4, 2021
    Publication date: October 27, 2022
    Applicant: Genentech, Inc.
    Inventors: Snahel Patel, Gregory Hamilton, Guiling Zhao, Huifen Chen
  • BICYCLIC KETONE COMPOUNDS AND METHODS OF USE THEREOF
    Publication number: 20210340151
    Abstract: Some embodiments of the invention provide compounds having the general formula I: wherein R1, R2, R3a and R3b are as described herein, pharmaceutical compositions including the compounds, and methods of using the compounds.
    Type: Application
    Filed: July 8, 2021
    Publication date: November 4, 2021
    Applicant: Genentech, Inc.
    Inventors: Snahel PATEL, Gregory HAMILTON, Guiling ZHAO, Huifen CHEN, Blake DANIELS, Craig STIVALA
  • Soil loosening and furrower assemblies and a bed renovator therefor
    Patent number: 11140802
    Abstract: There is provided soil loosening and furrower assemblies and a bed renovator therefor. The soil loosening assembly comprises a blade assembly and wherein the blade assembly is horizontally pitched such that, when drawn beneath a soil surface at a fixed depth, the horizontally pitched blade assembly severs rootstock at the level of the blade assembly while retaining the rootstock substantially in place and loosens soil above the level of the blade assembly without substantial soil inversion. The furrower assembly comprises side plates extending rearwardly from a forward prow edge, wherein the side plates are approximately 25-45° with respect to the horizontal axis; and bottom edges of the side plates are approximately 20-40° with respect to a direction-of-travel axis.
    Type: Grant
    Filed: December 17, 2019
    Date of Patent: October 12, 2021
    Assignee: MAXIMUM SOIL AND WATER PRODUCTIVITY PTY LTD
    Inventor: Gregory Hamilton
  • Bicyclic ketone compounds and methods of use thereof
    Patent number: 11098058
    Abstract: The invention provides novel compounds having the general formula I: wherein R1, the A ring and the B ring are as described herein, pharmaceutical compositions including the compounds, and methods of using the compounds.
    Type: Grant
    Filed: July 12, 2018
    Date of Patent: August 24, 2021
    Assignee: Genentech, Inc.
    Inventors: Snahel Patel, Gregory Hamilton, Guiling Zhao, Huifen Chen, Blake Daniels, Craig Stivala
  • Inhibitors of RIP1 kinase and methods of use thereof
    Patent number: 11072607
    Abstract: The invention provides novel compounds having RIP1 kinase inhibitory activity, pharmaceutical compositions including the compounds and methods of using the compounds.
    Type: Grant
    Filed: December 12, 2017
    Date of Patent: July 27, 2021
    Assignee: Genentech, Inc.
    Inventors: Snahel Patel, Gregory Hamilton
  • Bicyclic sulfones and sulfoxides and methods of use thereof
    Patent number: 11072617
    Abstract: The invention provides novel compounds having the general formula I: wherein R1, RB1, RB2, n, p, q, the A ring and the B ring are as described herein, pharmaceutical compositions including the compounds, and methods of using the compounds.
    Type: Grant
    Filed: October 30, 2018
    Date of Patent: July 27, 2021
    Assignee: Genentech, Inc.
    Inventors: Snahel Patel, Gregory Hamilton, Craig Stivala, Huifen Chen, Blake Daniels
  • Bicyclic amide compounds and methods of use thereof
    Patent number: 11071721
    Abstract: The invention provides novel compounds having the general formula I: wherein R1, R2, the A ring and the B ring are as described herein, pharmaceutical compositions including the compounds and methods of using the compounds.
    Type: Grant
    Filed: November 30, 2017
    Date of Patent: July 27, 2021
    Assignee: Genentech, Inc.
    Inventors: Snahel Patel, Gregory Hamilton, Guiling Zhao, Huifen Chen
  • THERAPEUTIC COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF
    Publication number: 20210179564
    Abstract: Compounds of Formula (I): and salts thereof, and methods of use as Janus kinase inhibitors are described herein.
    Type: Application
    Filed: February 17, 2021
    Publication date: June 17, 2021
    Applicant: Genentech, Inc.
    Inventors: James John Crawford, Mark Zak, Terry Kellar, Yun-Xing Cheng, Wei Li, F. Anthony Romero, Paul Gibbons, Guiling Zhao, Gregory Hamilton, Simon Charles Goodacre
  • BICYCLIC KETONE COMPOUNDS AND METHODS OF USE THEREOF
    Publication number: 20210139504
    Abstract: The invention provides novel compounds having the general formula I: wherein R1, the A ring and the B ring are as described herein, pharmaceutical compositions including the compounds, and methods of using the compounds.
    Type: Application
    Filed: January 12, 2021
    Publication date: May 13, 2021
    Applicant: Genentech, Inc.
    Inventors: Snahel PATEL, Gregory HAMILTON, Guiling ZHAO, Huifen CHEN, Blake DANIELS, Craig STIVALA