Abstract: Air elimination assemblies are described herein. An air elimination assembly for eliminating air from a flow of infusate includes a housing and a hydrophobic filter. The housing defines an infusate flow path having an inlet and an outlet, and an air flow path in fluid communication with the infusate flow path and disposed between the inlet and the outlet of the infusate flow path. The hydrophobic filter is disposed in fluid communication with the air flow path, wherein the hydrophobic filter is configured to permit air from the flow of infusate through a hydrophobic filter media and prevent the flow of infusate through the hydrophobic filter media.