Patents by Inventor Gregory J. Kellogg
Gregory J. Kellogg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10888862Abstract: A microfluidic system for processing biological samples comprising a holding chamber adapted for holding a fluid and to be rotated on a platform, said holding chamber comprising an outlet through which fluid flow is controlled by an acceleration-primed valve system, wherein the acceleration-primed valve system comprises a capillary valve and an outlet channel. The invention provides a novel valving system, which retains fluids at low angular velocities, removes the need for hydrophilic surfaces, minimises disc real-estate and optimises certain microfluidic processes done in the holding chamber.Type: GrantFiled: November 19, 2018Date of Patent: January 12, 2021Assignee: Radisens Diagnostics LimitedInventors: Gregory J. Kellogg, David Doolan, Donal Cronin
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Publication number: 20190091686Abstract: A microfluidic system for processing biological samples comprising a holding chamber adapted for holding a fluid and to be rotated on a platform, said holding chamber comprising an outlet through which fluid flow is controlled by an acceleration-primed valve system, wherein the acceleration-primed valve system comprises a capillary valve and an outlet channel. The invention provides a novel valving system, which retains fluids at low angular velocities, removes the need for hydrophilic surfaces, minimises disc real-estate and optimises certain microfluidic processes done in the holding chamber.Type: ApplicationFiled: November 19, 2018Publication date: March 28, 2019Applicant: Radisens Diagnostics LimitedInventors: Gregory J. Kellogg, David Doolan, Donal Cronin
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Patent number: 10130947Abstract: The invention relates to a microfluidic system for processing biological samples comprising a holding chamber adapted for holding a fluid and to be rotated on a platform, said holding chamber comprising an outlet through which fluid flow is controlled by an acceleration-primed valve system, wherein the acceleration-primed valve system comprises a capillary valve and an outlet channel. The invention provides a novel valving system, which retains fluids at low angular velocities, removes the need for hydrophilic surfaces, minimizes disc real-estate and optimizes certain microfluidic processes done in the holding chamber.Type: GrantFiled: December 5, 2013Date of Patent: November 20, 2018Assignee: Radisens Diagnostics LimitedInventor: Gregory J. Kellogg
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Patent number: 10058860Abstract: A treatment vessel may allow a user, or automated system, to manipulate sample material within a treatment area during processing (e.g., focused acoustic treatment), as well as subject the sample material to a staged processing protocol. The vessel may include openings for receiving/discharging the sample material. Walls within the vessel may be movable between various positions, to permit or obstruct flow of sample material into or out from a treatment area. The wall(s) may push the sample material within the vessel, as well as adjust pressure levels within the treatment area. In some embodiments, an acoustic treatment system may include a flexible coupling medium that may be deformed toward the vessel upon an application of suitable pressure thereto. When the medium presses up against the vessel, defects (e.g., particles, bubbles, interfaces, etc.) that may otherwise be present along the acoustic wave path may be reduced.Type: GrantFiled: August 4, 2015Date of Patent: August 28, 2018Assignee: Covaris, Inc.Inventors: James A. Laugharn, Jr., Gregory J. Kellogg
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Publication number: 20160038932Abstract: A treatment vessel may allow a user, or automated system, to manipulate sample material within a treatment area during processing (e.g., focused acoustic treatment), as well as subject the sample material to a staged processing protocol. The vessel may include openings for receiving/discharging the sample material. Walls within the vessel may be movable between various positions, to permit or obstruct flow of sample material into or out from a treatment area. The wall(s) may push the sample material within the vessel, as well as adjust pressure levels within the treatment area. In some embodiments, an acoustic treatment system may include a flexible coupling medium that may be deformed toward the vessel upon an application of suitable pressure thereto. When the medium presses up against the vessel, defects (e.g., particles, bubbles, interfaces, etc.) that may otherwise be present along the acoustic wave path may be reduced.Type: ApplicationFiled: August 4, 2015Publication date: February 11, 2016Applicant: Covaris, Inc.Inventors: James A. Laugharn, JR., Gregory J. Kellogg
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Publication number: 20080241844Abstract: This invention relates to methods and apparatus for performing microanalytic and microsynthetic analyses and procedures. The invention specifically provides devices and methods for performing miniaturized in vitro assays on biological samples, such as the polymerase chain reaction and Sanger sequencing reactions. Methods specific for the apparatus of the invention for performing PCR are provided.Type: ApplicationFiled: February 6, 2008Publication date: October 2, 2008Applicant: NETWORK BIOSYSTEMS, INC.Inventor: Gregory J. Kellogg
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Patent number: 7332326Abstract: This invention relates to methods and apparatus for performing microanalytic and microsynthetic analyses and procedures. The invention provides a microsystem platform and a micromanipulation device for manipulating the platform that utilizes the centripetal force resulting from rotation of the platform to motivate fluid movement through microchannels. The microsystem platforms of the invention are provided having arrays of thermal control regions, wherein fluid applied to the platform can be placed at a temperature and maintained at that temperature for a time that is dependent on the path length of the channel in the region, the cross-section dimension of the channel, and the rotational speed of the platform. Methods specific for the apparatus of the invention for performing any of a wide variety of microanalytical or microsynthetic processes are provided.Type: GrantFiled: May 12, 2000Date of Patent: February 19, 2008Assignee: Tecan Trading AGInventors: Gregory J. Kellogg, Bruce L. Carvalho, Norman F. Sheppard, Jr., Kevin E. Noonan
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Publication number: 20040259237Abstract: This invention relates to methods and apparatus for performing microanalytic and microsynthetic analyses and procedures. The invention provides a microsystem platform and a micromanipulation device for manipulating the platform that utilizes the centripetal force resulting from rotation of the platform to motivate fluid movement through microchannels. The invention specifically provides devices and methods for performing miniaturized in vitro amplification assays such as the polymerase chain reaction. Methods specific for the apparatus of the invention for performing PCR are provided.Type: ApplicationFiled: March 16, 2004Publication date: December 23, 2004Inventors: Gregory J. Kellogg, Charles Able, Todd Arnold, Bruce L. Carvalho, Hsin-Chiang Lin, Stephen Kieffer-Higgins, Norman F. Sheppard, Mikayla Kob, Shari Ommert
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Patent number: 6818435Abstract: This invention provides methods and apparatus for performing microanalytic analyses and procedures, particularly miniaturized cell based assays. These methods are useful for performing a variety of cell-based assays, including drug candidate screening, life sciences research, and clinical and molecular diagnostics.Type: GrantFiled: May 15, 2001Date of Patent: November 16, 2004Assignee: Tecan Trading AGInventors: Bruce L. Carvalho, Norman F. Sheppard, Jr., Christina Feakes, Gregory J. Kellogg
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Patent number: 6706519Abstract: This invention relates to methods and apparatus for performing microanalytic and microsynthetic analyses and procedures. The invention provides a microsystem platform and a micromanipulation device for manipulating the platform that utilizes the centripetal force resulting from rotation of the platform to motivate fluid movement through microchannels. The invention specifically provides devices and methods for performing miniaturized in vitro amplification assays such as the polymerase chain reaction. Methods specific for the apparatus of the invention for performing PCR are provided.Type: GrantFiled: June 22, 2000Date of Patent: March 16, 2004Assignee: Tecan Trading AGInventors: Gregory J. Kellogg, Charles Able, Todd Arnold, Bruce L. Carvalho, Hsin-Chiang Lin, Stephen Kieffer-Higgins, Norman F. Sheppard, Mikayla Kob, Shari Ommert
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Publication number: 20030152491Abstract: This invention relates to methods and apparatus for performing microanalytic and microsynthetic analyses and procedures. The invention particularly provides microsystem platforms for achieving efficient mixing of one or a plurality of fluids on the surface of the platform when fluid flow is motivated by centripetal force produce by rotation.Type: ApplicationFiled: March 4, 2003Publication date: August 14, 2003Applicant: Tecan Trading AG.Inventors: Gregory J. Kellogg, Bruce L. Carvalho
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Patent number: 6582662Abstract: This invention relates to methods and apparatus for performing microanalytic and microsynthetic analyzes and procedures. The invention provides a microsystem platform and a micromanipulation device for manipulating the platform that utilizes the centripetal force resulting from rotation of the platform to motivate fluid movement through microchannels. These assays may be performed for a variety of purposes, including but not limited to screening of drug candidate compounds, life sciences research, and clinical and molecular diagnostics. Methods specific for the apparatus of the invention for performing any of a wide variety of microanalytical or microsynthetic processes are provided.Type: GrantFiled: June 16, 2000Date of Patent: June 24, 2003Assignee: Tecan Trading AGInventors: Gregory J. Kellogg, David C. Duffy
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Patent number: 6527432Abstract: This invention relates to methods and apparatus for performing microanalytic and microsynthetic analyses and procedures. The invention particularly provides microsystem platforms for achieving efficient mixing of one or a plurality of fluids on the surface of the platform when fluid flow is motivated by centripetal force produce by rotation.Type: GrantFiled: May 15, 2001Date of Patent: March 4, 2003Assignee: Tecan Trading AGInventors: Gregory J. Kellogg, Bruce L. Carvalho
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Publication number: 20020151078Abstract: This invention relates to methods and apparatus for performing microanalytic and microsynthetic analyses and procedures. The invention provides a microsystem platform and a micromanipulation device for manipulating the platform that utilizes the centripetal force resulting from rotation of the platform to motivate fluid movement through microchannels. These assays may be performed for a variety of purposes, including but not limited to screening of drug candidate compounds, life sciences research, and clinical and molecular diagnostics. Methods specific for the apparatus of the invention for performing any of a wide variety of microanalytical or microsynthetic processes are provided.Type: ApplicationFiled: May 15, 2001Publication date: October 17, 2002Inventors: Gregory J. Kellogg, David Duffy, Aaron Pelta
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Publication number: 20020106786Abstract: This invention provides methods and apparatus for performing microanalytic analyses and procedures, particularly miniaturized cell based assays. These methods are useful for performing a variety of cell-based assays, including drug candidate screening, life sciences research, and clinical and molecular diagnostics.Type: ApplicationFiled: May 15, 2001Publication date: August 8, 2002Inventors: Bruce L. Carvalho, Norman F. Sheppard, Christina Feakes, Gregory J. Kellogg
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Publication number: 20020097632Abstract: This invention relates to methods and apparatus for performing microanalytic and microsynthetic analyses and procedures. The invention particularly provides microsystem platforms for achieving efficient mixing of one or a plurality of fluids on the surface of the platform when fluid flow is motivated by centripetal force produce by rotation.Type: ApplicationFiled: May 15, 2001Publication date: July 25, 2002Inventors: Gregory J. Kellogg, Bruce L. Carvalho