Abstract: A system and method using a gas discharge to provide for dermatological treatments, such as hair removal. The system provides for varying the spectral output of the gas discharge lamp by varying the current density through the lamp. This ability to control the spectral output is particularly beneficial where the a variety of different skin types and hair types are being treated for hair removal. By changing the current density through the lamp, the spectral output from the lamp can be changed. Thus, where a power supply provides the ability to control the amount of current density through the lamp, the spectral output from the lamp is controlled and selected for a particular skin type being treated.

Abstract: A system and method for providing treatments of electromagnetic radiation to areas of post-partum abdominal skin. The treatments provide for raising the temperature in a portion of post-partum abdominal skin to a treatment temperature, which is sufficient to reduce the laxity or redundancy of the post-partum skin. In one embodiment the treatment can provide treatment exposures to sub-areas, of an area of post-partum abdominal skin which has been identified for treatment, and bring a temperature of the tissue being treated to at 50° C.

Abstract: An implantable drug delivery device that uses multiple reservoir elements to contain and release doses of active pharmaceutical ingredients. The device includes a first shell element, which has a first enclosed cavity volume and forms a low-permeability barrier. The first shell element is configured to absorb light irradiation from a laser source, the laser irradiation causing a breach in the first shell element. A first active pharmaceutical ingredient is contained in the first enclosed cavity volume and is released when the first shell element is breached. The device also includes a second shell element, which has a second enclosed cavity volume and also forms a low-permeability barrier. A second active pharmaceutical ingredient is contained in the second enclosed cavity volume. The device also includes an envelope element containing the first and second shell elements.

Abstract: The present disclosure relates to methods for visualizing the opening of a drug reservoir of an implantable medical device. In particular, the present disclosure provides methods for observing the release or exposure of contents from a drug reservoir of a medical device placed within the vitreous of an eye of a subject. The methods include implanting a drug delivery device within an anatomy of a subject. The drug device includes a plurality of reservoirs, each loaded with a therapeutic agent and a marker. Furthermore, the drug delivery device comprises a plurality of barrier layers for separating the contents of one of the plurality of reservoirs from the anatomy. The method further includes irradiating at least one of the plurality of barrier layers such that at least one of the plurality of reservoirs is breached, thereby triggering release of the therapeutic agent and the marker from the device.

Abstract: A flashlamp device having a small diameter waveguide is disclosed for use in localized dermatological applications. A preferred waveguide has a curvilinear wall surface. The waveguide is supported by a plurality of spaced apart thermally-conductive elements in contact with the curvilinear wall surface allowing sufficient cooling of the waveguide while minimizing the amount of high angle light stripped from the waveguide at points of contact with the contact elements.

Abstract: A system and method for using a light source to treat tissue with NIR light. The operation provides for generating higher temperatures in deeper layers of tissue relative to shallower layers of tissue. The increased temperature in dermal layers can operate to induce collagen shrinkage, or remodeling. One of the light sources for providing a broad spectrum of NIR light is a filament light. The light from the filament lamp can be selectively filtered, and after filtering this light is applied to the skin, where the selective filtering can enhance the ability to elevate the temperature of deeper layers of tissue, relative to layers of tissue which are closer to the surface of the skin.