Patents by Inventor Gregory Joseph BAKER

Gregory Joseph BAKER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Ligand binding stabilization method for drug target identification
    Patent number: 8703438
    Abstract: Drug affinity responsive target stability (DARTS) is a method of drug target ID with several significant advantages over current techniques. In certain embodiments the method involves contacting a sample comprising one or more protein target(s) with a test agent to form a sample/test agent mixture; contacting the mixture with a protease; and identifying a protein or protein fragment that is protected from proteolysis, wherein the protection from proteolysis is an indicator that the protein or protein fragment binds to or interacts with the test agent.
    Type: Grant
    Filed: November 18, 2009
    Date of Patent: April 22, 2014
    Assignee: The Regents of the University of California
    Inventors: Jing Huang, Brett Eugene Lomenick, Rui Hao, Nao Jonai, Thomas M. Vondriska, Sarah Warburton, Gregory Joseph Baker, Mariam Aghajan
  • NOVEL AFFINITY BASED METHOD FOR DRUG TARGET IDENTIFICATION
    Publication number: 20100184112
    Abstract: Drug affinity responsive target stability (DARTS) is a novel method of drug target ID with several significant advantages over current techniques. In certain embodiments the method involves contacting a sample comprising one or more protein target(s) with a test agent to form a sample/test agent mixture; contacting the mixture with a protease; and identifying a protein or protein fragment that is protected from proteolysis, wherein the protection from proteolysis is an indicator that the protein or protein fragment binds to or interacts with the test agent.
    Type: Application
    Filed: November 18, 2009
    Publication date: July 22, 2010
    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: JING HUANG, Brett Eugene LOMENICK, Rui HAO, Nao JONAI, Thomas M. VONDRISKA, Sarah WARBURTON, Gregory Joseph BAKER, Mariam AGHAJAN