Abstract: This disclosure concerns fatty acid derivatives, pharmaceutical compositions comprising the fatty acid derivatives, and methods of using the fatty acid derivatives, for example, to treat inflammation, chronic itch, chronic pain, an autoimmune disorder, atherosclerosis, a skin disorder, arthritis, a neurodegenerative disorder, or a psychiatric disorder in a subject. In some embodiments, the fatty acid derivative is a compound, or a stereoisomer, tautomer, or pharmaceutically acceptable salt thereof, having a structure according to: wherein X is from 1-16 carbons in length, Z is aliphatic from 1-16 carbons in length, or is not present, Y is selected from: R1, R2, and R3 are independently hydrogen or lower alkyl, R4 is lower alkyl, hydroxyl, carboxyl, or amine, R5 is hydrogen, lower alkyl, or halide, R6 is hydroxyl or substituted thiol, and each R7 is independently hydrogen or fluoride or is not present and the adjacent carbons form alkyne.

Abstract: This disclosure concerns fatty acid derivatives, pharmaceutical compositions comprising the fatty acid derivatives, and methods of using the fatty acid derivatives, for example, to treat inflammation, chronic itch, chronic pain, an autoimmune disorder, atherosclerosis, a skin disorder, arthritis, a neurodegenerative disorder, or a psychiatric disorder in a subject. In some embodiments, the fatty acid derivative is a compound, or a stereoisomer, tautomer, or pharmaceutically acceptable salt thereof, having a structure according to: wherein X is from 1-16 carbons in length, Z is aliphatic from 1-16 carbons in length, or is not present, Y is selected from: R1, R2, and R3 are independently hydrogen or lower alkyl, R4 is lower alkyl, hydroxyl, carboxyl, or amine, R5 is hydrogen, lower alkyl, or halide, R6 is hydroxyl or substituted thiol, and each R7 is independently hydrogen or fluoride or is not present and the adjacent carbons form alkyne.

Abstract: This disclosure concerns fatty acid derivatives, pharmaceutical compositions comprising the fatty acid derivatives, and methods of using the fatty acid derivatives, for example, to treat inflammation, chronic itch, chronic pain, an autoimmune disorder, atherosclerosis, a skin disorder, arthritis, a neurodegenerative disorder, or a psychiatric disorder in a subject. In some embodiments, the fatty acid derivative is a compound, or a stereoisomer, tautomer, or pharmaceutically acceptable salt thereof, having a structure according to: wherein X is from 1-16 carbons in length, Z is aliphatic from 1-16 carbons in length, or is not present, Y is selected from: R1, R2, and R3 are independently hydrogen or lower alkyl, R4 is lower alkyl, hydroxyl, carboxyl, or amine, R5 is hydrogen, lower alkyl, or halide, R6 is hydroxyl or substituted thiol, and each R7 is independently hydrogen or fluoride or is not present and the adjacent carbons form alkyne.

Abstract: A device for removing liquid from a part of a vehicle, the liquid removal device including an intake (11) for receiving matter containing gaseous component and non-gaseous components, a separator (14) for separating the gaseous and non gaseous components of matter entering the inlet (11), and an outlet (9, 10) for directing a gaseous component of the matter leaving the separator (14) towards the part of the vehicle from which liquid is to be removed, so as to remove liquid therefrom.

Abstract: A device for removing liquid from a part of a vehicle, the liquid removal device including an intake (11) for receiving matter containing gaseous component and non-gaseous components, a separator (14) for separating the gaseous and non gaseous components of matter entering the inlet (11), and an outlet (9, 10) for directing a gaseous component of the matter leaving the separator (14) towards the part of the vehicle from which liquid is to be removed, so as to remove liquid therefrom.

Abstract: The invention relates to a motor vehicle door, consisting of an interior sheet metal and an exterior sheeting, together which form a hollow interior space of the door, having an opening in the interior sheet metal and having a carrier module that closes said opening, and carries at least one functional part of the motor vehicle door, such as a hinge part, lock part or window lifter part. In order to simplify the assembly of a motor vehicle door it is proposed that the vehicle door (10) features, apart from the opening (18) in the interior sheet metal (12) which may be closed by means of a carrier module, an additional access opening (22) adequately large for inserting the carrier module, including the at least one functional part, into the interior space (16) of the door and that the carrier module consists of a base plate (20) which closes the opening (18) of the interior sheet metal (12) from the side of the hollow interior space (16) of the door.

Abstract: A method of assembling of a door comprising the steps of providing a door inner panel having an outer face and an inner face, at least one functional component of the door, an anti intrusion beam and a door outer panel. The functional component is assembled onto and towards the outer face. The anti intrusion beam is assembled towards the outer face prior to assembling the door outer panel towards the outer face. Fixing means secure the door inner panel, the functional component, the anti intrusion beam and the door outer panel relative to each other.

Abstract: A method for manufacturing an optical compensator (5) on a transitional substrate (8) comprises applying a first orientation layer (20) to the transitional substrate. The first orientation layer (20) is then aligned and a first anisotropic liquid crystal material (30) is applied on the first orientation layer. In one embodiment, a retardation layer (10) is located between the transitional substrate (8) and the first orientation layer (20).

Abstract: A motor vehicle door includes structural parts for providing the rigidness of the vehicle door and includes a structural element and a lining element. The door further includes function components for providing vehicle door functions like a window panel with a regulator. At least one of the structural parts serves as a support of the function components. In order to reduce the number of individual components, at least one of the structural parts forms a completely shaped composite or sandwich part having a plastic based matrix and further having several of the function components included to serve a rigidness providing bodies. The bodies are molded into the plastic based matrix by the plastic based matrix.

Abstract: A method of assembling of a door comprising the steps of providing a door inner panel having an outer face and an inner face, at least one functional component of the door, an anti intrusion beam and a door outer panel. The functional component is assembled onto and towards the outer face. The anti intrusion beam is assembled towards the outer face prior to assembling the door outer panel towards the outer face. Fixing means secure the door inner panel, the functional component, the anti intrusion beam and the door outer panel relative to each other.

Abstract: A passenger door having a self engaging latch for latching the door in a closed position, the door further including a plurality of fixing bolts positioned about the periphery of the door to further secure the door in a closed position.