Patents by Inventor Gregory L. Moore

Gregory L. Moore has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190330342
    Abstract: The present invention relates to immunoglobulins that bind Fc?RIIb+ cells and coengage the antigen on the cell's surface and an Fc?RIIb on the cell's surface, methods for their generation, and methods for using the immunoglobulins.
    Type: Application
    Filed: July 9, 2019
    Publication date: October 31, 2019
    Applicant: XENCOR, INC.
    Inventors: Seung Yup Chu, John R. Desjarlais, Sher Bahadur Karki, Gregory Alan Lazar, Gregory L. Moore, Igor Vostiar
  • Publication number: 20190315861
    Abstract: The present invention relates to immunoglobulins that bind Fc?RIIb+ cells and coengage the antigen on the cell's surface and an Fc?RIIb on the cell's surface, methods for their generation, and methods for using the immunoglobulins.
    Type: Application
    Filed: May 21, 2019
    Publication date: October 17, 2019
    Applicant: XENCOR, INC.
    Inventors: Seung Yup Chu, John R. Desjarlais, Sher Bahadur Karki, Gregory Alan Lazar, Gregory L. Moore, Igor Vostiar
  • Patent number: 10427813
    Abstract: A method of packaging products and a packaging arrangement. A first product unit is wrapped at least in a first protective cover. The first protective cover envelops the first product unit and creates a first wrapped first product unit. A second product is wrapped at least in a second protective cover, such that the second protective cover envelops the second product unit and creates a second wrapped second product unit. The first wrapped first product unit is arranged adjacent to the second wrapped second product unit to create a product unit arrangement. A band is formed circumferentially around the product unit arrangement to create a secured product unit arrangement. The band has at least one graphic. The secured product unit arrangement is wrapped in a protective wrapper. The protective wrapper is heated to shrink the wrapper around the secured product unit arrangement. The graphic remains intact and visible.
    Type: Grant
    Filed: June 14, 2017
    Date of Patent: October 1, 2019
    Assignee: GPCP IP Holdings LLC
    Inventors: Gregory D. Moore, Tracey L. Meckley, Michael S. Dwyer
  • Patent number: 10376444
    Abstract: A method includes micro-machining a cavity within a substrate, filling the cavity with a medication, forming a sealing layer over the cavity, micro-machining a cantilevered beam from a layer of material, the cantilevered beam comprising a tip for puncturing the sealing layer, and attaching the cantilevered beam to the substrate such that moving the cantilevered beam toward the substrate enables the tip to puncture the sealing layer. A computer program product corresponding to the method is also disclosed. An apparatus includes a substrate having a cavity micro-machined therein, a sealing layer formed over the cavity, a medication disposed within the cavity, a cantilevered beam micro-machined from a layer of material, the cantilevered beam comprising a tip for puncturing the sealing layer, and the cantilevered beam attached to the substrate and disposed to enable the tip to puncture the sealing layer when the cantilevered beam is moved towards the substrate.
    Type: Grant
    Filed: March 22, 2016
    Date of Patent: August 13, 2019
    Assignee: International Business Machines Corporation
    Inventors: Ira L. Allen, Gregory J. Boss, Lawrence A. Clevenger, Andrew R. Jones, Kevin C. McConnell, John E. Moore, Jr.
  • Publication number: 20190243866
    Abstract: Mobile enablement of a web site, in one aspect, may comprise separating the web application into a static content and a dynamic content, the dynamic content comprising one or more data sources from which to retrieve data at runtime of the web application; rendering the static content as one or more hypertext markup language pages with one or more links between the hypertext markup language pages converted to local links; changing one or more references to the dynamic content to representational state transfer requests; enabling the representational state transfer requests from said one or more hypertext markup language pages; and packaging said one or more hypertext markup language pages as the mobile application.
    Type: Application
    Filed: April 22, 2019
    Publication date: August 8, 2019
    Inventors: Erik J. Burckart, Gennaro A. Cuomo, Dinakaran Joseph, Todd E. Kaplinger, Victor S. Moore, Gregory L. Truty
  • Patent number: 10368194
    Abstract: Locating misplaced mobile computing devices through transmission of location information. Mobile computing devices periodically request information from surrounding mobile computing devices to more accurately identify the location where a mobile computing device was misplaced.
    Type: Grant
    Filed: February 20, 2017
    Date of Patent: July 30, 2019
    Assignee: International Business Machines Corporation
    Inventors: Ira L. Allen, Gregory J. Boss, Andrew R. Jones, Kevin C. McConnell, John E. Moore, Jr.
  • Patent number: 10346501
    Abstract: Mobile enablement of a web site, in one aspect, may comprise separating the web application into a static content and a dynamic content, the dynamic content comprising one or more data sources from which to retrieve data at runtime of the web application; rendering the static content as one or more hypertext markup language pages with one or more links between the hypertext markup language pages converted to local links; changing one or more references to the dynamic content to representational state transfer requests; enabling the representational state transfer requests from said one or more hypertext markup language pages; and packaging said one or more hypertext markup language pages as the mobile application.
    Type: Grant
    Filed: March 13, 2013
    Date of Patent: July 9, 2019
    Assignee: International Business Machines Corporation
    Inventors: Erik J. Burckart, Gennaro A. Cuomo, Dinakaran Joseph, Todd E. Kaplinger, Victor S. Moore, Gregory L. Truty
  • Patent number: 10346502
    Abstract: Mobile enablement of a web site, in one aspect, may comprise separating the web application into a static content and a dynamic content, the dynamic content comprising one or more data sources from which to retrieve data at runtime of the web application; rendering the static content as one or more hypertext markup language pages with one or more links between the hypertext markup language pages converted to local links; changing one or more references to the dynamic content to representational state transfer requests; enabling the representational state transfer requests from said one or more hypertext markup language pages; and packaging said one or more hypertext markup language pages as the mobile application.
    Type: Grant
    Filed: November 1, 2013
    Date of Patent: July 9, 2019
    Assignee: International Business Machines Corporation
    Inventors: Erik J. Burckart, Gennaro A. Cuomo, Dinakaran Joseph, Todd E. Kaplinger, Victor S. Moore, Gregory L. Truty
  • Publication number: 20180215821
    Abstract: The present invention relates to immunoglobulins that bind Fc?RIIb+ cells and coengage the antigen on the cell's surface and an Fc?RIIb on the cell's surface, methods for their generation, and methods for using the immunoglobulins.
    Type: Application
    Filed: February 9, 2018
    Publication date: August 2, 2018
    Applicant: XENCOR, INC.
    Inventors: Seung Yup Chu, John R. Desjarlais, Sher Bahadur Karki, Gregory Alan Lazar, Gregory L. Moore, Igor Vostiar
  • Publication number: 20180215822
    Abstract: The present invention relates to immunoglobulins that bind Fc?RIIb+ cells and coengage the antigen on the cell's surface and an Fc?RIIb on the cell's surface, methods for their generation, and methods for using the immunoglobulins.
    Type: Application
    Filed: February 9, 2018
    Publication date: August 2, 2018
    Applicant: XENCOR, INC.
    Inventors: Seung Yup Chu, John R. Desjarlais, Sher Bahadur Karki, Gregory Alan Lazar, Gregory L. Moore, Igor Vostiar
  • Publication number: 20180201686
    Abstract: The present invention relates to rapid clearance molecules that bind target antigens and Fc?RIIb with increased affinity as compared to parent molecules, said compositions being capable of causing accelerated clearance of such antigens. Such compositions are useful for treating a variety of disorders, including allergic diseases, atherosclerosis, and a variety of other conditions.
    Type: Application
    Filed: August 21, 2017
    Publication date: July 19, 2018
    Inventors: Gregory L. Moore, John Desjarlais, Matthew Bernett
  • Patent number: 9914778
    Abstract: The present invention relates to immunoglobulins that bind Fc?RIIb+ cells and coengage the antigen on the cell's surface and an Fc?RIIb on the cell's surface, methods for their generation, and methods for using the immunoglobulins.
    Type: Grant
    Filed: July 10, 2014
    Date of Patent: March 13, 2018
    Assignee: Xencor, Inc.
    Inventors: Seung Yup Chu, John R. Desjarlais, Sher Bahadur Karki, Gregory Alan Lazar, Gregory L. Moore, Igor Vostiar
  • Patent number: 9902773
    Abstract: The present invention relates to immunoglobulins that bind Fc?RIIb+ cells and coengage the antigen on the cell's surface and an Fc?RIIb on the cell's surface, methods for their generation, and methods for using the immunoglobulins.
    Type: Grant
    Filed: July 10, 2014
    Date of Patent: February 27, 2018
    Assignee: Xencor, Inc.
    Inventors: Seung Yup Chu, John R. Desjarlais, Sher Bahadur Karki, Gregory Alan Lazar, Gregory L. Moore, Igor Vostiar
  • Publication number: 20170247470
    Abstract: The present invention relates to immunoglobulins that bind IgE and Fc?RIIb with high affinity, said compositions being capable of inhibiting cells that express membrane-anchored IgE. Such compositions are useful for treating IgE-mediated disorders, including allergies and asthma.
    Type: Application
    Filed: January 15, 2014
    Publication date: August 31, 2017
    Applicant: Xencor, Inc.
    Inventors: Gregory L. Moore, John Desjarlais
  • Patent number: 9738722
    Abstract: The present invention relates to rapid clearance molecules that bind target antigens and Fc?RIIb with increased affinity as compared to parent molecules, the compositions being capable of causing accelerated clearance of such antigens. Such compositions are useful for treating a variety of disorders, including allergic diseases, atherosclerosis, and a variety of other conditions.
    Type: Grant
    Filed: January 15, 2014
    Date of Patent: August 22, 2017
    Assignee: Xencor, Inc.
    Inventors: Gregory L. Moore, John Desjarlais, Matthew Bernett
  • Patent number: 9701759
    Abstract: The invention provides heterodimeric antibodies comprising a first heavy chain comprising a first Fc domain and a single chain Fv region that binds a first antigen. The heterodimeric antibodies also comprise a second heavy chain comprising a second Fc domain, a first variable heavy chain and a first variable light chain, wherein the first and second Fc domains are different.
    Type: Grant
    Filed: January 14, 2014
    Date of Patent: July 11, 2017
    Assignee: Xencor, Inc.
    Inventors: John R. Desjarlais, Gregory L. Moore, Rumana Rashid, Matthew J. Bernett
  • Patent number: 9493578
    Abstract: Immunoglobulin compositions that simultaneously co-engage antigens, where one of the antigens is bound bivalently and the other antigen is bound monovalently. The novel immunoglobulins described preferably utilize heterodimeric Fc regions.
    Type: Grant
    Filed: September 2, 2010
    Date of Patent: November 15, 2016
    Assignee: Xencor, Inc.
    Inventors: Gregory A. Lazar, Gregory L. Moore
  • Patent number: 9475881
    Abstract: The present invention relates to novel Fc variants that comprise at least one novel amino acid residue which may provide for enhanced effector function. More specifically, this invention provides Fc variants that have modified binding affinity to one or more Fc receptor or ligand (e.g., Fc gamma R, C1q). Additionally, the Fc variants have altered complement dependent cytotoxicity (CDC) activity and/or antibody-dependent cell-mediated cytotoxicity (ADCC). The invention further provides methods and protocols for the application of said Fc variants, particularly for therapeutic purposes.
    Type: Grant
    Filed: January 22, 2013
    Date of Patent: October 25, 2016
    Assignee: Xencor, Inc.
    Inventors: Gregory A. Lazar, Sher Bahadur Karki, Gregory L. Moore
  • Patent number: 9394366
    Abstract: The present invention relates to immunoglobulins that bind Fc?RIIb+ cells and coengage the antigen on the cell's surface and an Fc?RIIb on the cell's surface, methods for their generation, and methods for using the immunoglobulins.
    Type: Grant
    Filed: November 29, 2012
    Date of Patent: July 19, 2016
    Assignee: Xencor, Inc.
    Inventors: Seung Yup Chu, John R. Desjarlais, Sher Bahadur Karki, Gregory Alan Lazar, Gregory L. Moore, Igor Vostiar
  • Publication number: 20160122435
    Abstract: The present invention relates to immunoglobulins that bind Fc?RIIb+ cells and coengage the antigen on the cell's surface and an Fc?RIIb on the cell's surface, methods for their generation, and methods for using the immunoglobulins.
    Type: Application
    Filed: January 11, 2016
    Publication date: May 5, 2016
    Applicant: Xencor, Inc.
    Inventors: Seung Yup Chu, John R. Desjarlais, Sher Bahadur Karki, Gregory Alan Lazar, Gregory L. Moore, Igor Vostiar