Patents by Inventor Gregory L. Pearce
Gregory L. Pearce has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9109039Abstract: A 23 amino acid peptide, AtPep1, plays an important role as a signaling component of the innate immune system of Arabidopsis. The peptide precursor gene is transcribed in response to elicitors generated by pathogens, and AtPep1 is produced to amplify the signaling pathways. Seven paralogs of the AtproPep1 gene have been identified in the Arabidopsis genome, and orthologs have been identified in species of several agriculturally important families. AtPep1 and its paralogs and orthologs play important roles as endogenous signals to amplify innate immunity. The sequences of two AtPep1 receptors from Arabidopsis are also provided.Type: GrantFiled: January 31, 2014Date of Patent: August 18, 2015Assignee: Washington State UniversityInventors: Clarence A. Ryan, Gregory L. Pearce, Alisa Huffaker, Yube Yamaguchi
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Publication number: 20140137298Abstract: A 23 amino acid peptide, AtPep1, plays an important role as a signaling component of the innate immune system of Arabidopsis. The peptide precursor gene is transcribed in response to elicitors generated by pathogens, and AtPep1 is produced to amplify the signaling pathways. Seven paralogs of the AtproPep1 gene have been identified in the Arabidopsis genome, and orthologs have been identified in species of several agriculturally important families. AtPep1 and its paralogs and orthologs play important roles as endogenous signals to amplify innate immunity. The sequences of two AtPep1 receptors from Arabidopsis are also provided.Type: ApplicationFiled: January 31, 2014Publication date: May 15, 2014Applicant: Washington State University Research FoundationInventors: Clarence A. Ryan, Gregory L. Pearce, Alisa Huffaker, Yube Yamaguchi
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Patent number: 8686224Abstract: A 23 amino acid peptide, AtPep1, plays an important role as a signaling component of the innate immune system of Arabidopsis. The peptide precursor gene is transcribed in response to elicitors generated by pathogens, and AtPep1 is produced to amplify the signaling pathways. Seven paralogs of the AtproPep1 gene have been identified in the Arabidopsis genome, and orthologs have been identified in species of several agriculturally important families. AtPep1 and its paralogs and orthologs play important roles as endogenous signals to amplify innate immunity. The sequences of two AtPep1 receptors from Arabidopsis are also provided.Type: GrantFiled: August 23, 2012Date of Patent: April 1, 2014Assignee: Washington State University Research FoundationInventors: Gregory L. Pearce, Alisa Huffaker, Yube Yamaguchi, Patricia Louise Ryan
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Publication number: 20090300802Abstract: A 23 amino acid peptide, AtPep1, plays an important role as a signaling component of the innate immune system of Arabidopsis. The peptide precursor gene is transcribed in response to elicitors generated by pathogens, and AtPep1 is produced to amplify the signaling pathways. Seven paralogs of the AtproPep1 gene have been identified in the Arabidopsis genome, and orthologs have been identified in species of several agriculturally important families. AtPep1 and its paralogs and orthologs play important roles as endogenous signals to amplify innate immunity. The sequences of two AtPep1 receptors from Arabidopsis are also provided.Type: ApplicationFiled: April 14, 2009Publication date: December 3, 2009Inventors: Clarence A. Ryan, Patricia Louise Ryan, Gregory L. Pearce, Alisa Huffaker, Yube Yamaguchi
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Publication number: 20090119793Abstract: A 23 amino acid peptide, AtPtpl, plays an important role as a signaling component of the innate immune system of Arabidopsis. The peptide precursor gene is transcribed in response to elicitors generated by pathogens, and AtPep1 is produced to amplify the signaling pathways. Seven paralogs of the AtproPep1 gene have been identified in the Arabidopsis genome, and orthologs have been identified in species of several agriculturally important families. AtPcpl and its paralogs and orthologs play important roles as endogenous signals to amplify innate immunity. The sequence of two AtPep1 receptors from Arabidopsis are also provided.Type: ApplicationFiled: January 24, 2006Publication date: May 7, 2009Applicant: Washington State University Research FoundationInventors: Clarence A. Ryan, Patricia Louise Ryan, Gregory L. Pearce, Alisa Huffaker, Yube Yamaguchi
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Publication number: 20030217389Abstract: In one aspect, the present invention provides isolated RALF polypeptides that are useful for stimulating the growth of plant meristem cells. In another aspect, the present invention provides isolated nucleic acid molecules that are at least 90% identical to a nucleic acid molecule (SEQ ID NO: 2) that encodes a tobacco RALF precursor polypeptide (SEQ ID NO: 3). In a further aspect, the present invention provides isolated polypeptides that are at least 90% identical to the amino acid sequence of a tobacco RALF precursor polypeptide (SEQ ID NO: 3). In another aspect, the present invention provides vectors and plant cells comprising a vector of the invention. In other aspects, the present invention provides methods of inhibiting meristem growth in a plant, and methods of enhancing meristem growth in a plant.Type: ApplicationFiled: October 28, 2002Publication date: November 20, 2003Inventors: Clarence A Ryan, Gregory L Pearce, Daniel Scherer de Moura
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Publication number: 20030211941Abstract: The present invention provides methods for identifying and isolating signalling molecules, such as signalling molecules that interact with a plant cell membrane receptor molecule. In the practice of the present invention, the ability of a sample of biological material to induce a pH change in a liquid plant cell culture is used as an assay for the presence of one or more signalling molecules in the biological material.Type: ApplicationFiled: October 22, 2002Publication date: November 13, 2003Inventors: Clarence A. Ryan, Gregory L. Pearce
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Publication number: 20020183491Abstract: A rapid and simple method of isolating heat stable proteinase inhibitor proteins from plant tissues such as potato tubers is disclosed. The method comprises three steps. Proteins from potato tubers are extracted in an aqueous/alcohol extraction medium to form an alcohol extract. The alcohol extract is heated to a first temperature then cooled to a second temperature to form an insoluble precipitate phase containing debris and a soluble phase that contains the heat stable proteinase inhibitor proteins. The heat stable proteinase inhibitor proteins are precipitated from the soluble phase by dialysis against a suitable dialysis medium. The precipitated proteins may include a single inhibitor protein, or a mixture thereof.Type: ApplicationFiled: May 7, 2002Publication date: December 5, 2002Applicant: Washington State University Research FoundationInventors: Clarence A. Ryan, Gregory L. Pearce
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Patent number: 6414124Abstract: A rapid and simple method of isolating heat stable proteinase inhibitor proteins from plant tissues such as potato tubers is disclosed. The method comprises three steps. Proteins from potato tubers are extracted in an aqueous/alcohol extraction medium to form an alcohol extract. The alcohol extract is heated to a first temperature then cooled to a second temperature to form an insoluble precipitate phase containing debris and a soluble phase that contains the heat stable proteinase inhibitor proteins. The heat stable proteinase inhibitor proteins are precipitated from the soluble phase by dialysis against a suitable dialysis medium. The precipitated proteins may include a single inhibitor protein, or a mixture thereof.Type: GrantFiled: December 29, 1999Date of Patent: July 2, 2002Assignee: Washington State Research FoundationInventors: Clarence A. Ryan, Gregory L. Pearce
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Patent number: 6022739Abstract: Systemin, an 18 amino acid peptide hormone and first polypeptide hormone found in plants, induces expression of defense genes in plants wounded mechanically or by predators including herbivores, insects, bacteria and viruses. The precursor for systemin is encoded as a 200 amino acid prosystemin molecule that has the systemin peptide sequence located near the carboxyl-terminus. Both a 951 bp cDNA for prosystemin and 4526 bp genomic DNA were cloned and the organization of the gene was determined. Transgenic plants constructed with antisense prosystemin DNA fail to mount a defensive response to wounding. Transgenic plants constructed with increased copy number of prosystemin genes exhibit increased resistance to wounding. Insect larval that feed on transgenic plants constructed with increased copy number of prosystemin genes exhibit decreased growth weight compared to larval that feed on wild type plants.Type: GrantFiled: July 9, 1997Date of Patent: February 8, 2000Assignee: Washington State University Research Foundation, Inc.Inventors: Clarence A. Ryan, Gregory L. Pearce, Barry F. McGurl
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Patent number: 5883076Abstract: Systemin, an 18 amino acid peptide hormone and first polypeptide hormone found in plants, induces expression of defense genes in plants wounded mechanically or by predators including herbivores, insects, bacteria and viruses. The precursor for systemin is encoded as a 200 amino acid prosystemin molecule that has the systemin peptide sequence located near the carboxyl-terminus. Both a 951 bp cDNA for prosystemin and 4526 bp genomic DNA were cloned and the organization of the gene was determined. Transgenic plants constructed with antisense prosystemin DNA fail to mount a defensive response to wounding. Transgenic plants constructed with increased copy number of prosystemin genes exhibit increased resistance to wounding. Insect larval that feed on transgenic plants constructed with increased copy number of prosystemin genes exhibit decreased growth weight compared to larval that feed on wild type plants. A tomato systemin polypeptide has an amino acid sequence NH.sub.3 -AVQSKPPSKRDPPKMQTD-COO-.Type: GrantFiled: September 19, 1994Date of Patent: March 16, 1999Assignee: Washington State University Research Foundation, Inc.Inventors: Clarence A. Ryan, Gregory L. Pearce, Barry F. McGurl
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Patent number: 5378819Abstract: Systemin is an 18 amino acid peptide hormone that induces expression of defense genes in plants wounded mechanically or by predators including herbivores, insects, bacteria and viruses. The precursor for systemin is encoded as a 200 amino acid prosystemin molecule that has the systemin peptide sequence located near the carboxy-terminus. Both a 951 bp cDNA for prosystemin and 4526 bp genomic DNA were cloned and the organization of the gene was determined. Transgenic plants constructed with antisense prosystemin DNA fail to mount a defensive response to wounding. Transgenic plants constructed with increased copy number of prosystemin genes exhibit increase resistance to wounding. A tomato systemin polypeptide has an amino acid sequence NH.sub.3 --AVQSKPPSKRDPPKMQTD--COO--.Type: GrantFiled: March 19, 1992Date of Patent: January 3, 1995Assignee: Washington State University Research FoundationInventors: Clarence A. Ryan, Gregory L. Pearce, Barry F. McGurl