Abstract: A method may enable a benefits consultant or other user to quantitatively compare competing PBM formularies across a representative sample of all drugs covered under a health benefits plan to present a comprehensive analysis of the formulary and its influence on a client's net cost. The method may determine a client's utilization data under the client's current formulary schedule. Also, it may determine a pharmacy benefits manager's (PBM) book of business utilization data under the PBM's formulary schedule. Further, the method may determine the utilization differences between the client's utilization data under the current formulary and the PBM's book of business utilization data under the PBM's formulary. Using the client and PBM utilization differences, the method may extrapolate a projected total cost for the client under the PBM's formulary.

Abstract: The present invention relates to quinolines, pharmaceutical compositions containing them and their use as antagonists of urotensin II.

Abstract: The present invention relates to quinolines, pharmaceutical compositions containing them and their use as antagonists of urotensin II.

Abstract: We have found it possible to investigate subsurface formations in the expectation of locating promising gas fields by a unique refraction seismic technique. Basically one carries out a two-way seismic refraction profile for a fixed spread of geophones and explosions (or equivalent impulse sources) beyond the critical reflection range for shallow refractors, but still rather close to the spread. Then without moving the spread, reproducible records are also made for a two-way seismic refraction profile with the explosions or equivalent sources spaced as far away as convenient, so the refraction paths to the detector groups in the spread is up-going to the detectors for the maximum thickness of beds intervening between the refractor and the group of geophones.