Patents by Inventor Gregory Lambert

Gregory Lambert has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11389489
    Abstract: The present invention relates to pharmaceutical and food compositions for inducing satiation and prolonging satiety in subjects in need thereof. In particular, the present invention relates to a method of inducing satiation in a subject in need thereof comprising administering to the subject an effective amount of a ClpB protein or an effective amount of a bacterium that expresses the ClpB protein.
    Type: Grant
    Filed: June 8, 2020
    Date of Patent: July 19, 2022
    Assignees: INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE), CENTRE HOSPITALIER UNIVERSITAIRE DE ROUEN, UNIVERSITE DE ROUEN, TARGEDYS
    Inventors: Serguei Fetissov, Pierre Dechelotte, Jonathan Breton, Gregory Lambert, Naouel Tennoune, Romain Legrand
  • Patent number: 11369645
    Abstract: The present invention relates to method of preventing, treating or attenuating obesity-related manifestations in a human or non-human mammal subject in need thereof, said method comprising orally administering to the subject a composition comprising an effective amount Hafnia alvei probiotics; wherein said obesity-related parameters are selected from the group of hyperphagia, increased fat mass on lean mass ratio, increased waist circumference, postprandial hyperglycemia, fasting hyperglycemia and hypercholesterolemia.
    Type: Grant
    Filed: June 16, 2020
    Date of Patent: June 28, 2022
    Assignees: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), CENTRE HOSPITALIER UNIVERSITAIRE DE ROUEN, UNIVERSITE DE ROUEN, TARGEDYS
    Inventors: Serguei Fetissov, Pierre Dechelotte, Jonathan Breton, Gregory Lambert, Nicolas Lucas, Romain Legrand
  • Patent number: 11319352
    Abstract: Methods of treating inflammation, in particular obesity, inducing satiation, prolonging satiety, and stimulating weight loss in a subject in need thereof, including the administration of a Brassicaceae protein extract. The Brassicaceae protein extract may be administered in the form of a dietary supplement or a food composition, either of which may include at least one additional ingredient.
    Type: Grant
    Filed: April 3, 2018
    Date of Patent: May 3, 2022
    Assignees: TARGEDYS, INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE), UNIVERSITÉ DE ROUEN
    Inventors: Serguei Fetissov, Grégory Lambert, Romain Legrand, Nicolas Lucas
  • Publication number: 20220058519
    Abstract: In an approach for managing an open feature library, a processor collects feature metadata from a data source, the feature metadata being data related to features for training a machine learning model. A processor builds a feature pipeline for the features based on the collected feature metadata. The feature pipeline may be a set of defined and active features. A processor executes the feature pipeline including computing the features. A processor executes a machine learning model using the computed features. A processor evaluates the features and corresponding model results.
    Type: Application
    Filed: August 24, 2020
    Publication date: February 24, 2022
    Inventors: Eugene Irving Kelton, Brandon Harris, Willie Robert Patten, JR., Russell Gregory Lambert
  • Publication number: 20220058341
    Abstract: A semantic, machine readable language part that supports the specification of features is used by an engine that interprets that language to produce the features based on the raw data. In this way, the model developer can specify the measurement columns (for example, data fields), to obtain the dimensions from which the engine can compute the multiple combinations of features possible based on this set of input fields. This computation of features can be used to perform machine learning (ML) training and/or scoring algorithms (for example, ML algorithms for fraud detection).
    Type: Application
    Filed: August 20, 2020
    Publication date: February 24, 2022
    Inventors: Russell Gregory Lambert, Eugene Irving Kelton, Jacob McPherson, Willie Robert Patten, JR.
  • Publication number: 20220058015
    Abstract: In an approach for optimizing an open feature library, a processor identifies redundancy among a set of features, the set of features previously executed in a machine learning model. A processor performs a predecessor evaluation, the predecessor evaluation including recognizing a feature in the set of features being executed and analyzing an impact of making an upstream feature configuration change relating to the feature. A processor performs a successor evaluation, the successor evaluation including recognizing the feature in the set of features being executed and analyzing an impact of making a downstream feature configuration change relating to the feature. A processor rates the feature against a goal, the goal including overall execution time and overall execution footprint in the machine learning model. A processor updates a state of the feature based on the predecessor evaluation, the successor evaluation, and the feature rating.
    Type: Application
    Filed: August 24, 2020
    Publication date: February 24, 2022
    Inventors: Eugene Irving Kelton, Russell Gregory Lambert, Willie Robert Patten, JR., Brandon Harris
  • Publication number: 20220000941
    Abstract: A pharmaceutical or nutraceutical composition, including a Hafnia alvei strain probiotic composition; the strain expressing the ClpB protein; in association with zinc bisglycinate and/or chrome picolinate. Additionally, oral dosage forms of the pharmaceutical or nutraceutical composition including the Hafnia alvei strain probiotic composition in association with zinc bisglycinate and/or chrome picolinate.
    Type: Application
    Filed: November 28, 2019
    Publication date: January 6, 2022
    Applicant: TARGEDYS
    Inventors: Clémentine PICOLO, Grégory LAMBERT
  • Publication number: 20210401020
    Abstract: A composition essentially made of a Hafnia alvei probiotic strain expressing the ClpB protein; wherein the ClpB protein is in an amount of at least 0.7% (w/w) in weight relative to the total weight of the composition; and the ratio of the total number of Hafnia alvei Colony Forming Units to the total Hafnia alvei cell number ranges from 10?4 to 0.8. Also, oral dosage forms, namely gastro-resistant capsules including the composition of essentially made of a Hafnia alvei probiotic strain expressing the ClpB protein.
    Type: Application
    Filed: November 28, 2019
    Publication date: December 30, 2021
    Applicants: TARGEDYS, CENTRE HOSPITALIER UNIVERSITAIRE DE ROUEN, INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE), UNIVERSITÉ DE ROUEN
    Inventors: Clémentine PICOLO, Grégory LAMBERT, Romain LEGRAND, Nicolas LUCAS
  • Publication number: 20210350487
    Abstract: Computer vision and deep learning techniques are leveraged to detect behavior patterns in transaction histories. A transaction timeline is built for a series of transactions, e.g., financial, and a graphic image is constructed representing the transaction timeline. The graphic image is then matched to a known behavior pattern using a cognitive system. The cognitive system is trained with historical timeline images having associated labels. In one example the graphic image is a bar chart and each financial transaction is represented as a bar in the bar chart having a height proportional to a transaction amount, the bar being located along a time axis of the bar chart according to the transaction date and being color coded according to the transaction type.
    Type: Application
    Filed: May 5, 2020
    Publication date: November 11, 2021
    Inventors: Eugene I. Kelton, Brandon Harris, Willie R. Patten, JR., Eliza Salkeld, Russell Gregory Lambert, Yi-Hui Ma, Shuyan Lu, Shanna Hayes
  • Publication number: 20210107952
    Abstract: Methods of treating inflammation, in particular obesity, inducing satiation, prolonging satiety, and stimulating weight loss in a subject in need thereof, including the administration of a Brassicaceae protein extract. The Brassicaceae protein extract may be administered in the form of a dietary supplement or a food composition, either of which may include at least one additional ingredient.
    Type: Application
    Filed: April 3, 2018
    Publication date: April 15, 2021
    Applicants: TARGEDYS, INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE), UNIVERSITÉ DE ROUEN
    Inventors: Serguei FETISSOV, Grégory LAMBERT, Romain LEGRAND, Nicolas LUCAS
  • Publication number: 20210038721
    Abstract: Compositions containing quaternary compounds in which the nitrogen atom is substituted by at least one alkyl group having at least 12 carbon atoms, and the composition includes at least 20% in weight by weight of the total composition, of ammonium halides in which the nitrogen atom is substituted by at least one alkyl group having at least 14 carbon atoms and more than 5%, preferably more than 7% in weight by weight of the total composition, of ammonium halides in which the nitrogen atom is substituted by at least one alkyl group having at least 16 carbon atoms. Also, ophthalmic oil-in-water emulsions containing such compositions, the ophthalmic emulsions being useful for eye care or for the treatment of eye conditions.
    Type: Application
    Filed: October 21, 2020
    Publication date: February 11, 2021
    Inventors: Laura RABINOVICH-GUILATT, Gregory LAMBERT, Frederic LALLEMAND, Betty PHILIPS
  • Publication number: 20210008125
    Abstract: The present invention relates to method of preventing, treating or attenuating obesity-related manifestations in a human or non-human mammal subject in need thereof, said method comprising orally administering to the subject a composition comprising an effective amount Hafnia alvei probiotics; wherein said obesity-related parameters are selected from the group of hyperphagia, increased fat mass on lean mass ratio, increased waist circumference, postprandial hyperglycemia, fasting hyperglycemia and hypercholesterolemia.
    Type: Application
    Filed: June 16, 2020
    Publication date: January 14, 2021
    Inventors: Serguei Fetissov, Emmanuelle De, Naouel Tennoune, Jonathan Breton, Philippe Chan-Tchi-Song, Pierre Dechelotte, Romain Legrand, Gregory Lambert
  • Patent number: 10888592
    Abstract: The present invention relates to pharmaceutical and food compositions for inducing satiation and prolonging satiety in subjects in need thereof. In particular, the present invention relates to a method of inducing satiation in a subject in need thereof comprising administering to the subject an effective amount of Hafnia alvei.
    Type: Grant
    Filed: April 5, 2017
    Date of Patent: January 12, 2021
    Assignees: TARGEDYS, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)
    Inventors: Serguei Fetissov, Pierre Dechelotte, Jonathan Breton, Gregory Lambert, Romain Legrand, Nicolas Lucas
  • Patent number: 10842873
    Abstract: Compositions containing quaternary compounds in which the nitrogen atom is substituted by at least one alkyl group having at least 12 carbon atoms, and the composition includes at least 20% in weight by weight of the total composition, of ammonium halides in which the nitrogen atom is substituted by at least one alkyl group having at least 14 carbon atoms and more than 5%, preferably more than 7% in weight by weight of the total composition, of ammonium halides in which the nitrogen atom is substituted by at least one alkyl group having at least 16 carbon atoms. Also, ophthalmic oil-in-water emulsions containing such compositions, the ophthalmic emulsions being useful for eye care or for the treatment of eye conditions.
    Type: Grant
    Filed: April 5, 2018
    Date of Patent: November 24, 2020
    Assignee: SANTEN SAS
    Inventors: Laura Rabinovich-Guilatt, Gregory Lambert, Frederic Lallemand, Betty Philips
  • Publication number: 20200297783
    Abstract: The present invention relates to pharmaceutical and food compositions for inducing satiation and prolonging satiety in subjects in need thereof. In particular, the present invention relates to a method of inducing satiation in a subject in need thereof comprising administering to the subject an effective amount of a ClpB protein or an effective amount of a bacterium that expresses the ClpB protein.
    Type: Application
    Filed: June 8, 2020
    Publication date: September 24, 2020
    Inventors: Serguei FETISSOV, Pierre DECHELOTTE, Jonathan BRETON, Gregory LAMBERT, Naouel TENNOUNE, Romain LEGRAND
  • Patent number: 10729770
    Abstract: The present invention relates to ClpB expressing bacteria and their impact on obesity. The present invention relates to bacterial ClpB protein and ClpB expressing bacteria and their impact on eating disorders. The invention further relates to compositions comprising antibiotic directed against at least one ClpB expressing bacterium as well as probiotics not expressing ClpB protein and their use in the treatment or prevention of eating disorders. The invention also relates to diagnostic tools for determining whether a subject is likely to respond to a method of treating eating disorders and to methods of immunization against eating disorders.
    Type: Grant
    Filed: July 11, 2018
    Date of Patent: August 4, 2020
    Assignees: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), CENTRE HOSPITALIER UNIVERSITAIRE DE ROUEN, UNIVERSITE DE ROUEN, TARGEDYS
    Inventors: Serguei Fetissov, Emmanuelle De, Naouel Tennoune, Jonathan Breton, Philippe Chan-Tchi-Song, Pierre Dechelotte, Romain Legrand, Gregory Lambert
  • Patent number: 10682389
    Abstract: The present invention relates to pharmaceutical and food compositions for inducing satiation and prolonging satiety in subjects in need thereof. In particular, the present invention relates to a method of inducing satiation in a subject in need thereof comprising administering to the subject an effective amount of a ClpB protein or an effective amount of a bacterium that expresses the ClpB protein.
    Type: Grant
    Filed: April 5, 2016
    Date of Patent: June 16, 2020
    Assignees: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), CENTRE HOSPITALIER UNIVERSITAIRE DE ROUEN, UNIVERSITÉ´DE ROUEN, TARGEDYS
    Inventors: Sergueï Fetissov, Pierre Dechelotte, Jonathan Breton, Gregory Lambert, Romain Legrand
  • Publication number: 20200131495
    Abstract: Polypeptides and proteins that include a fragment of a ClpB protein and compositions therefrom. Methods of treatment and/or prevention of inflammation, in particular overweight and/or obesity-related diseases and disorders, with the polypeptides and proteins. Also, methods of inducing satiation, prolonging satiety, reducing meal size, reducing food intake, controlling weight gain and stimulating weight loss with the polypeptides and proteins.
    Type: Application
    Filed: April 3, 2018
    Publication date: April 30, 2020
    Applicants: TARGEDYS, INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE), UNIVERSITÉ DE ROUEN
    Inventors: Serguei FETISSOV, Grégory LAMBERT, Romain LEGRAND, Nicolas LUCAS, Manon DOMINIQUE
  • Publication number: 20200000924
    Abstract: Compositions containing quaternary compounds in which the nitrogen atom is substituted by at least one alkyl group having at least 12 carbon atoms, and the composition includes at least 20% in weight by weight of the total composition, of ammonium halides in which the nitrogen atom is substituted by at least one alkyl group having at least 14 carbon atoms and more than 5%, preferably more than 7% in weight by weight of the total composition, of ammonium halides in which the nitrogen atom is substituted by at least one alkyl group having at least 16 carbon atoms. Also, ophthalmic oil-in-water emulsions containing such compositions, the ophthalmic emulsions being useful for eye care or for the treatment of eye conditions.
    Type: Application
    Filed: April 5, 2018
    Publication date: January 2, 2020
    Inventors: Laura RABINOVICH-GUILATT, Gregory LAMBERT, Frederic LALLEMAND, Betty PHILIPS
  • Publication number: 20190142876
    Abstract: The present invention relates to pharmaceutical and food compositions for inducing satiation and prolonging satiety in subjects in need thereof. In particular, the present invention relates to a method of inducing satiation in a subject in need thereof comprising administering to the subject an effective amount of Hafnia alvei.
    Type: Application
    Filed: April 5, 2017
    Publication date: May 16, 2019
    Inventors: Serguei FETISSOV, Pierre DECHELOTTE, Jonathan BRETON, Gregory LAMBERT