Patents by Inventor Gregory Landes

Gregory Landes has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CONJUGATED ANTI-CD38 ANTIBODIES
    Publication number: 20140155584
    Abstract: Isolated antibodies that bind to human CD38 and cynomolgus CD38 are disclosed. Also disclosed are pharmaceutical compositions comprising the disclosed antibodies, and therapeutic and diagnostic methods for using the disclosed antibodies.
    Type: Application
    Filed: December 30, 2011
    Publication date: June 5, 2014
    Applicant: Takeda Pharmaceutical Company Limited
    Inventors: Kathleen Ann Elias, Gregory Landes, Shweta Singh, Wouter Korver, Andrew Walling Drake, Mary Haak-Frendscho, Gyorgy Pal Snell, Vinay Bhaskar
  • Monoclonal antibodies against ANGPTL3
    Patent number: 8742075
    Abstract: Monoclonal antibodies that specifically bind to ANGPTL3 are provided. Monoclonal antibodies that neutralize at least one activity of ANGPTL3 are provided. Methods of treating a disorder of lipid metabolism using neutralizing monoclonal antibodies are provided.
    Type: Grant
    Filed: March 28, 2011
    Date of Patent: June 3, 2014
    Assignee: Lexicon Pharmaceuticals, Inc.
    Inventors: E-Chiang Lee, Gregory Landes, Seokjoo Hong, Urvi Desai, David Powell, Xiao Feng
  • ANTIBODIES THAT BIND NOTUM PECTINACETYLESTERASE
    Publication number: 20130302346
    Abstract: Antibodies that neutralize Notum Pectinacetylesterase are described, as well as compositions comprising them, and methods of their use to treat diseases and disorders affecting the bone.
    Type: Application
    Filed: November 22, 2011
    Publication date: November 14, 2013
    Applicant: LEXICON PHARMACEUTICALS, INC.
    Inventors: Robert Joseph Brommage, JR., Xiao Feng, Seokjoo Hong, Gregory Landes, Jeff Liu, David George Potter, David Reed Powell
  • Anti-CD38 antibodies
    Patent number: 8362211
    Abstract: Isolated antibodies that bind to human CD38 and cynomolgus CD38 are disclosed. Also disclosed are pharmaceutical compositions comprising the disclosed antibodies, and therapeutic and diagnostic methods for using the disclosed antibodies.
    Type: Grant
    Filed: December 30, 2011
    Date of Patent: January 29, 2013
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Kathleen Ann Elias, Gregory Landes, Shweta Singh, Wouter Korver, Andrew Walling Drake, Mary Haak-Frendscho, Gyorgy Pal Snell, Vinay Bhaskar
  • ANTI-CD38 ANTIBODIES
    Publication number: 20120201827
    Abstract: Isolated antibodies that bind to human CD38 and cynomolgus CD38 are disclosed. Also disclosed are pharmaceutical compositions comprising the disclosed antibodies, and therapeutic and diagnostic methods for using the disclosed antibodies.
    Type: Application
    Filed: December 30, 2011
    Publication date: August 9, 2012
    Applicant: Takeda Pharmaceutical Company Limited
    Inventors: Kathleen Ann Elias, Gregory Landes, Shweta Singh, Wouter Korver, Andrew Walling Drake, Mary Haak-Frendscho, Gyorgy Pal Snell, Vinay Bhaskar
  • Monoclonal Antibodies Against ANGPTL3
    Publication number: 20110243948
    Abstract: Monoclonal antibodies that specifically bind to ANGPTL3 are provided. Monoclonal antibodies that neutralize at least one activity of ANGPTL3 are provided. Methods of treating a disorder of lipid metabolism using neutralizing monoclonal antibodies are provided.
    Type: Application
    Filed: March 28, 2011
    Publication date: October 6, 2011
    Applicant: LEXICON PHARMACEUTICALS, INC.
    Inventors: E-Chiang Lee, Gregory Landes, Seokjoo Hong, Urvi Desai, David Powell, Xiao Feng
  • Monoclonal antibodies against ANGPTL3
    Patent number: 7935796
    Abstract: Monoclonal antibodies that specifically bind to ANGPTL3 are provided. Monoclonal antibodies that neutralize at least one activity of ANGPTL3 are provided. Methods of treating a disorder of lipid metabolism using neutralizing monoclonal antibodies are provided.
    Type: Grant
    Filed: December 6, 2007
    Date of Patent: May 3, 2011
    Assignee: Lexicon Pharmaceuticals, Inc.
    Inventors: E-Chiang Lee, Gregory Landes, Seokjoo Hong, Urvi Desai, David Powell, Xiao Feng
  • Monoclonal antibodies against ANGPTL3
    Publication number: 20080177045
    Abstract: Monoclonal antibodies that specifically bind to ANGPTL3 are provided. Monoclonal antibodies that neutralize at least one activity of ANGPTL3 are provided. Methods of treating a disorder of lipid metabolism using neutralizing monoclonal antibodies are provided.
    Type: Application
    Filed: December 6, 2007
    Publication date: July 24, 2008
    Inventors: E-Chiang Lee, Gregory Landes, Seokjoo Hong, Urvi Desai, David Powell
  • Methods for reducing complexity of a sample using small epitope antibodies
    Publication number: 20070042431
    Abstract: The present invention relates generally to methods for reducing the complexity of a sample. More specifically, the present invention relates to proteomics, the measurement of the protein levels in biological samples, and analysis of proteins in a sample using antibodies that recognize small epitopes.
    Type: Application
    Filed: October 23, 2006
    Publication date: February 22, 2007
    Applicant: Tethys Bioscience, Inc.
    Inventors: Michael Urdea, Gregory Landes, Gregory Went
  • Monoclonal antibodies against ANGPTL4
    Publication number: 20060222645
    Abstract: Monoclonal antibodies that specifically bind to ANGPTL4 are provided. Monoclonal antibodies that neutralize at least one activity of ANGPTL4 are provided. Methods of treating a disorder of lipid metabolism using neutralizing monoclonal antibodies are provided.
    Type: Application
    Filed: January 6, 2006
    Publication date: October 5, 2006
    Inventors: E-Chiang Lee, Gregory Landes, Kyu Chung, Ling Chen, Urvi Desai, David Powell, Seokjoo Hong
  • Methods for reducing complexity of a sample using small epitope antibodies
    Publication number: 20050131219
    Abstract: The present invention relates generally to methods for reducing the complexity of a sample. More specifically, the present invention relates to proteomics, the measurement of the protein levels in biological samples, and analysis of proteins in a sample using antibodies that recognize small epitopes.
    Type: Application
    Filed: August 18, 2004
    Publication date: June 16, 2005
    Inventors: Michael Urdea, Gregory Landes, Gregory Went
  • Antibodies against T cell immunoglobulin domain and mucin domain 1 (TIM-1) antigen and uses thereof
    Publication number: 20050084449
    Abstract: The invention described herein is related to antibodies directed to the antigen TIM-1 and uses of such antibodies. In particular, there are provided fully human monoclonal antibodies directed to the antigen TIM-1. Isolated polynucleotide sequences encoding, and amino acid sequences comprising, heavy and light chain immunoglobulin molecules, particularly sequences corresponding to contiguous heavy and light chain sequences spanning the framework regions (FR's) and/or complementarity determining regions (CDR's), specifically from FR1 through FR4 or CDR1 through CDR3, are provided. Hybridomas or other cell lines expressing such immunoglobulin molecules and monoclonal antibodies are also provided.
    Type: Application
    Filed: March 19, 2004
    Publication date: April 21, 2005
    Inventors: Gregory Landes, Francine Chen, Binyam Bezabeh, Ian Foltz, Kam Tse, Michael Jeffers, Mehdi Mesri, Gary Starling, Peter Mezes, Nikolia Khramtsov
  • Antibodies directed to phospholipase A2 and uses thereof
    Publication number: 20050058649
    Abstract: The invention described herein relates to antibodies directed to the antigen phospholipase A2 (PLA2) and uses of such antibodies. In particular, in accordance with some embodiments of the invention, there are provided fully human monoclonal antibodies directed to the antigen PLA2. Nucleotide sequences encoding, and amino acid sequences comprising, heavy and light chain immunoglobulin molecules, particularly sequences corresponding to contiguous heavy and light chain sequences spanning the framework regions and/or complementarity determining regions (CDRs), specifically from FR1 through FR4 or CDR1 through CDR3, are provided. Hybridomas or other cell lines expressing such immunoglobulin molecules and monoclonal antibodies are also provided.
    Type: Application
    Filed: December 2, 2003
    Publication date: March 17, 2005
    Inventors: Gregory Landes, Mary Haak-Frendscho, Ling Chen, Yen-Wah Lee, Meina Liang, Xiao Feng, Xiao-Chi Jia, Mark Nocerini
  • Polycystic kidney disease gene and protein
    Patent number: 6071717
    Abstract: The present invention involves isolated nucleic acid encoding human PKD1, and sequences derived therefrom. The invention also encompasses vectors comprising these nucleic acids, host cells transformed with the vectors, and methods for producing PKD1 protein or fragments thereof. In another aspect, the invention involves isolated oligonucleotides that hybridize only to the authentic expressed PKD1 gene, and not to PKD1 homologues. In yet another aspect, the invention involves isolated mutant PKD1 genes, and their cDNA cognates. Further provided are isolated oligonucleotides that discriminate between normal and mutant versions of the PKD1 gene. Methods and compositions for treating APKD or disease conditions having the characteristics of APKD are also provided.
    Type: Grant
    Filed: June 4, 1996
    Date of Patent: June 6, 2000
    Assignees: Genzyme Corporation, Johns Hopkins University
    Inventors: Katherine Klinger, Timothy Burn, Timothy Connors, William Dackowski, Gregory Germino, Feng Qian, Gregory Landes
  • Human chromosome 16 genes, compositions, methods of making and using same
    Patent number: 6028173
    Abstract: This invention provides an isolated human netrin polypeptide. Netrins define a family of diffusable factors involved in axon outgrowth.
    Type: Grant
    Filed: June 17, 1996
    Date of Patent: February 22, 2000
    Assignee: Genzyme Corporation
    Inventors: Gregory Landes, Timothy Burn, Timothy Connors, William Dackowski, Terence Van Raay, Katherine Klinger