Abstract: A composition of furosemide, or a pharmaceutically acceptable salt, solvate, or physiologically functional derivative thereof is combined with a steroid, or a pharmaceutically acceptable salt, solvate, or physiologically functional derivative thereof, to provide a topical medication for nasal or pulmonary treatment. The composition can provide, in a single administration or dosing regime, the anti-inflammatory properties of the steroid and the anti-inflammatory properties of furosemide, without any significant interference between the two, or adverse reaction in situ. One of the components is microencapsulated so that the components are released into the patient's bloodstream at different times, even when administered simultaneously.

Abstract: A composition of furosemide, or a pharmaceutically acceptable salt, solvate, or physiologically functional derivative thereof is combined with a steroid, or a pharmaceutically acceptable salt, solvate, or physiologically functional derivative thereof, to provide a topical medication for nasal or pulmonary treatment. The composition can provide, in a single administration or dosing regime, the anti-inflammatory properties of the steroid and the anti-inflammatory properties of furosemide, without any significant interference between the two, or adverse reaction in situ.