Patents by Inventor Gregory M. Husar

Gregory M. Husar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and devices for performing high dynamic range immunoassays
    Patent number: 10451615
    Abstract: A method for performing a high dynamic range immunoassay includes (a) measuring a first signal from a sandwich immunoassay to detect a target analyte in a fluidic sample in a fluidic channel and a second signal from a competitive immunoassay associated with the target analyte in the same fluidic sample in the fluidic channel, and (b) determining ratio of the first signal to the second signal to provide a measure of concentration of the target analyte in the fluidic sample, wherein the measure is applicable to a high dynamic range of concentrations of the target analyte.
    Type: Grant
    Filed: December 4, 2015
    Date of Patent: October 22, 2019
    Assignee: MBio Diagnostics, Inc.
    Inventors: Gregory M. Husar, Sarah Rachel Bickman, Michael J. Lochhead
  • METHODS AND DEVICES FOR PERFORMING HIGH DYNAMIC RANGE IMMUNOASSAYS
    Publication number: 20160161474
    Abstract: A method for performing a high dynamic range immunoassay includes (a) measuring a first signal from a sandwich immunoassay to detect a target analyte in a fluidic sample in a fluidic channel and a second signal from a competitive immunoassay associated with the target analyte in the same fluidic sample in the fluidic channel, and (b) determining ratio of the first signal to the second signal to provide a measure of concentration of the target analyte in the fluidic sample, wherein the measure is applicable to a high dynamic range of concentrations of the target analyte.
    Type: Application
    Filed: December 4, 2015
    Publication date: June 9, 2016
    Inventors: Gregory M. Husar, Sarah Rachel Bickman, Michael J. Lochhead
  • Method for immobilizing oligonucleotides employing the cycloaddition bioconjugation method
    Patent number: 7427678
    Abstract: This invention discloses a novel method for immobilizing molecules to a support. Specifically, this invention discloses a method of immobilizing derivatized biomolecules, such as oligonucleotides, using cycloaddition reactions, such as the Diels-Alder reaction. Included in this invention are the novel immobilized biomolecules that can be prepared according to the method of this invention.
    Type: Grant
    Filed: May 1, 2001
    Date of Patent: September 23, 2008
    Assignee: Sigma-Aldrich Co.
    Inventors: Wolfgang Pieken, Andreas Wolter, David P. Sebesta, Michael Leuck, Hallie A. Latham-Timmons, John Pilon, Gregory M. Husar
  • Method for immobilizing oligonucleotides employing the cycloaddition bioconjugation method
    Publication number: 20030215801
    Abstract: This invention discloses a novel method for immobilizing molecules to a support. Specifically, this invention discloses a method of immobilizing derivatized biomolecules, such as oligonucleotides, using cycloaddition reactions, such as the Diels-Alder reaction. Included in this invention are the novel immobilized biomolecules that can be prepared according to the method of this invention.
    Type: Application
    Filed: May 1, 2001
    Publication date: November 20, 2003
    Inventors: Wolfgang Pieken, Andreas Wolter, David P. Sebesta, Michael Leuck, Hallie A. Latham-Timmons, John Pilon, Gregory M. Husar