Patents by Inventor Gregory M. Lawrence
Gregory M. Lawrence has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240077438Abstract: An apparatus and method for an inspection apparatus for inspecting a component. The inspection apparatus including a robotic arm. A micro-XRF instrument having an instrument head coupled to the robotic arm. A seat supporting the component within a scanning area during inspection; and a computer in communication with the robotic arm and the micro-XRF instrument.Type: ApplicationFiled: November 10, 2023Publication date: March 7, 2024Inventors: Richard DiDomizio, Michael Christopher Andersen, Walter Vincent Dixon, III, Timothy Hanlon, Wayne Lee Lawrence, Ramkumar Kashyap Oruganti, Jonathan Rutherford Owens, Daniel M. Ruscitto, Adarsh Shukla, Eric John Telfeyan, Gregory Donald Crim, Michael Wylie Krauss, André Dziurla, Sven Martin Joachim Larisch, Falk Reinhardt, Roald Alberto Tagle Berdan, Henning Schroeder
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Publication number: 20220236265Abstract: The present disclosure provides methods and lateral flow devices for detecting a plurality of target analytes in a liquid sample. In some implementations, the disclosed lateral flow device comprises a housing unit, a capillary flow bed, a sample-receiving zone, a buffer-receiving zone, and a capture zone. The device is configured to control the flow of the sample and reagent buffer in a sequential manner with minimal mixing. In some implementations, the disclosed method is capable of detecting a plurality of target analytes in an assay by applying the binding agents and the signaling agents in separate or sequential steps.Type: ApplicationFiled: April 4, 2022Publication date: July 28, 2022Inventors: Gregory M. Lawrence, Adam P. Lousararian, Yli Remo Vallejo, Lisa Shinefeld
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Patent number: 11293922Abstract: The present disclosure provides methods and lateral flow devices for detecting a plurality of target analytes in a liquid sample. In some implementations, the disclosed lateral flow device comprises a housing unit, a capillary flow bed, a sample-receiving zone, a buffer-receiving zone, and a capture zone. The device is configured to control the flow of the sample and reagent buffer in a sequential manner with minimal mixing. In some implementations, the disclosed method is capable of detecting a plurality of target analytes in an assay by applying the binding agents and the signaling agents in separate or sequential steps.Type: GrantFiled: July 27, 2018Date of Patent: April 5, 2022Assignee: Verax Biomedical IncorporatedInventors: Yli Remo Vallejo, Gregory M. Lawrence, Adam P. Lousararian, Lisa Shinefeld
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Publication number: 20190079085Abstract: The present disclosure provides methods and lateral flow devices for detecting a plurality of target analytes in a liquid sample. In some implementations, the disclosed lateral flow device comprises a housing unit, a capillary flow bed, a sample-receiving zone, a buffer-receiving zone, and a capture zone. The device is configured to control the flow of the sample and reagent buffer in a sequential manner with minimal mixing. In some implementations, the disclosed method is capable of detecting a plurality of target analytes in an assay by applying the binding agents and the signaling agents in separate or sequential steps.Type: ApplicationFiled: July 27, 2018Publication date: March 14, 2019Inventors: Gregory M. Lawrence, Yli Remo Vallejo, Adam P. Lousararian, Lisa Shinefeld
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Publication number: 20160011185Abstract: The present invention is directed to devices and methods using pan-generic antibodies to detect bacteria in a sample. The invention relates to binding assays, especially immunoassays, utilizing a multivalent binding agent immobilized on a particle. The invention also relates to the surprising discovery that increasing the size of the particles improves the sensitivity of the screen.Type: ApplicationFiled: March 4, 2014Publication date: January 14, 2016Inventors: Gregory M. Lawrence, Lisa Shinefeld
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Patent number: 9182418Abstract: A bodily fluid analyzer including a dry test strip impregnated with a reagent providing a non-precipitating reaction to exclude non-desired analytes. The reagent complexes the non-desired analytes so they remain in solution but cannot participate in the test reaction. Red blood cells are removed from the detection area by slowing their vertical movement and stopping flow when the detection membrane is saturated.Type: GrantFiled: January 31, 2014Date of Patent: November 10, 2015Assignee: Polymer Technology Systems, Inc.Inventors: Gregory M. Lawrence, Meredith Knight
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Publication number: 20150241424Abstract: The present invention is directed to devices and methods using pan-generic antibodies to detect bacteria in a sample.Type: ApplicationFiled: October 7, 2013Publication date: August 27, 2015Inventors: Gregory M. Lawrence, Lisa Shinefeld
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Publication number: 20140147870Abstract: A bodily fluid analyzer including a dry test strip impregnated with a reagent providing a non-precipitating reaction to exclude non-desired analytes. The reagent complexes the non-desired analytes so they remain in solution but cannot participate in the test reaction. Red blood cells are removed from the detection area by slowing their vertical movement and stopping flow when the detection membrane is saturated.Type: ApplicationFiled: January 31, 2014Publication date: May 29, 2014Applicant: Polymer Technology Systems, Inc.Inventors: Gregory M. Lawrence, Meredith Knight
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Patent number: 8642320Abstract: A bodily fluid analyzer including a dry test strip impregnated with a reagent providing a non-precipitating reaction to exclude non-desired analytes. The reagent complexes the non-desired analytes so they remain in solution but cannot participate in the test reaction. Red blood cells are removed from the detection area by slowing their vertical movement and stopping flow when the detection membrane is saturated.Type: GrantFiled: October 16, 2009Date of Patent: February 4, 2014Assignee: Polymer Technology Systems, Inc.Inventors: Gregory M. Lawrence, Meredith Knight
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Patent number: 8465696Abstract: A dry test strip assembly includes: a carrier base having a test port and a well adapted for receiving a dry test strip element, and a cover having a sample opening. The cover can be snapped onto the base with the sample opening aligned over the test port and with a test strip element compressed between the base and cover. A maximum dry test strip compression stop controls the maximum compression on the dry test strip, and a minimum dry test strip compression stop controls the minimum compression on the dry test strip. A rib between two test ports prevents fluid flow in the dry test strip element from one side of the rib to another, thereby separating the test strip element into a plurality of separate fluid compartments. A manufacturing system efficiently assembles the dry test strip assembly without handling by humans.Type: GrantFiled: October 31, 2007Date of Patent: June 18, 2013Assignee: Polymer Technology Systems, Inc.Inventors: Robert Huffstodt, John P. Hancock, Emmanuel Paul Crabtree, James J. Sutor, Kimberly Zinser Huffstodt, Gregory M. Lawrence
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Patent number: 8307531Abstract: There is a dry test strip holder having a test port and a retainer defining a well about the test port, and a sheet of test strip material. A test element that is 50% or less greater than the size of the test port is cut from the sheet using a die and punch. The punch drives the test element through a channel in the die while the cone-shaped outer surface of the die spreads the retainer, allowing the test element to drop into the well. A cap is snapped over the retainer to capture the test element.Type: GrantFiled: May 3, 2010Date of Patent: November 13, 2012Assignee: Polymer Technology Systems, Inc.Inventor: Gregory M. Lawrence
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Publication number: 20100205797Abstract: There is a dry test strip holder having a test port and a retainer defining a well about the test port, and a sheet of test strip material. A test element that is 50% or less greater than the size of the test port is cut from the sheet using a die and punch. The punch drives the test element through a channel in the die while the cone-shaped outer surface of the die spreads the retainer, allowing the test element to drop into the well. A cap is snapped over the retainer to capture the test element.Type: ApplicationFiled: May 3, 2010Publication date: August 19, 2010Applicant: Polymer Technology Systems, Inc.Inventor: Gregory M. Lawrence
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Publication number: 20100041066Abstract: A bodily fluid analyzer including a dry test strip impregnated with a reagent providing a non-precipitating reaction to exclude non-desired analytes. The reagent complexes the non-desired analytes so they remain in solution but cannot participate in the test reaction. Red blood cells are removed from the detection area by slowing their vertical movement and stopping flow when the detection membrane is saturated.Type: ApplicationFiled: October 16, 2009Publication date: February 18, 2010Applicant: Polymer Technology Systems, Inc.Inventors: Gregory M. Lawrence, Meredith Knight
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Patent number: 7625721Abstract: A bodily fluid analyzer including a dry test strip impregnated with a reagent providing a non-precipitating reaction to exclude non-desired analytes. The reagent complexes the non-desired analytes so they remain in solution but cannot participate in the test reaction. Red blood cells are removed from the detection area by slowing their vertical movement and stopping flow when the detection membrane is saturated.Type: GrantFiled: August 17, 2005Date of Patent: December 1, 2009Assignee: Polymer Technology Systems, Inc.Inventors: Gregory M. Lawrence, Meredith Knight
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Patent number: 7435577Abstract: Cholesterol from Low Density Lipoproteins (LDL-C) is measured directly with a test strip at room temperature using a reagent that takes advantage of the varying surface charge density on LDLs and non-LDLs to selectively make LDL-C available for testing.Type: GrantFiled: October 11, 2004Date of Patent: October 14, 2008Assignee: Polymer Technology Systems, Inc.Inventors: Gregory M. Lawrence, John Pasqua
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Publication number: 20080112848Abstract: A dry test strip assembly includes: a carrier base having a test port and a well adapted for receiving a dry test strip element, and a cover having a sample opening. The cover can be snapped onto the base with the sample opening aligned over the test port and with a test strip element compressed between the base and cover. A maximum dry test strip compression stop controls the maximum compression on the dry test strip, and a minimum dry test strip compression stop controls the minimum compression on the dry test strip. A rib between two test ports prevents fluid flow in the dry test strip element from one side of the rib to another, thereby separating the test strip element into a plurality of separate fluid compartments. A manufacturing system efficiently assembles the dry test strip assembly without handling by humans.Type: ApplicationFiled: October 31, 2007Publication date: May 15, 2008Applicant: Polymer Technology Systems, Inc.Inventors: Robert Huffstodt, John P. Hancock, Emmanuel P. Crabtree, James J. Sutor, Kimberly Zinser Huffstodt, Gregory M. Lawrence