Patents by Inventor Gregory Maes

Gregory Maes has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for detection, staging, and surveillance of colorectal adenomas and carcinomas
    Patent number: 11933785
    Abstract: This invention provides minimally invasive methods, reagents, diagnostic and prognostic markers useful for staging, prognosis and surveillance of colorectal cancers, and therapeutic intervention in individuals with colorectal cancers, or individuals who may be susceptible to developing colorectal cancers.
    Type: Grant
    Filed: June 12, 2017
    Date of Patent: March 19, 2024
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Michael Richard Sussman, Melanie Mae Ivancic, Gregory D Kennedy, William Franklin Dove, Perry Joseph Pickhardt, Mark Reichelderfer
  • HIGH-THROUGHPUT GENOTYPING BY SEQUENCING LOW AMOUNTS OF GENETIC MATERIAL
    Publication number: 20220186291
    Abstract: The present invention provides a method for analysis of target nucleic acids which are present in low amounts. In particular, the method comprises the following steps: i. providing a sample wherein target nucleic acids are present in a low amount, ii. generating a reduced representation library of said target nucleic acids by a method comprising: fragmenting said target nucleic acids; ligating adaptors to said fragments; and selecting a subset of said adaptor-ligated fragments, iii. massively parallel sequencing said reduced representation library, and iv. identifying variants in said target nucleic acids by analyzing results obtained by said sequencing.
    Type: Application
    Filed: February 28, 2022
    Publication date: June 16, 2022
    Inventors: Joris Vermeesch, Thierry Voet, Femke Hannes, Jeroen Van Houdt, Gregory Maes
  • HIGH-THROUGHPUT GENOTYPING BY SEQUENCING LOW AMOUNTS OF GENETIC MATERIAL
    Publication number: 20200291456
    Abstract: The present invention provides a method for analysis of target nucleic acids which are present in low amounts. In particular, the method comprises the following steps: i. providing a sample wherein target nucleic acids are present in a low amount, ii. generating a reduced representation library of said target nucleic acids by a method comprising: —fragmenting said target nucleic acids; ligating adaptors to said fragments; and selecting a subset of said adaptor-ligated fragments, iii. massively parallel sequencing said reduced representation library, and iv. identifying variants in said target nucleic acids by analyzing results obtained by said sequencing.
    Type: Application
    Filed: May 20, 2020
    Publication date: September 17, 2020
    Inventors: Joris Vermeesch, Thierry Voet, Femke Hannes, Jeroen Van Houdt, Gregory Maes
  • HIGH-THROUGHPUT GENOTYPING BY SEQUENCING LOW AMOUNTS OF GENETIC MATERIAL
    Publication number: 20150247184
    Abstract: The present invention provides a method for analysis of target nucleic acids which are present in low amounts. In particular, the method comprises the following steps: i. providing a sample wherein target nucleic acids are present in a low amount, ii. generating a reduced representation library of said target nucleic acids by a method comprising: fragmenting said target nucleic acids; ligating adaptors to said fragments; and selecting a subset of said adaptor-ligated fragments, iii. massively parallel sequencing said reduced representation library, and iv. identifying variants in said target nucleic acids by analyzing results obtained by said sequencing.
    Type: Application
    Filed: October 7, 2013
    Publication date: September 3, 2015
    Applicant: Katholieke Universiteit Leuven
    Inventors: Joris Vermeesch, Thierry Voet, Femke Hannes, Jeroen Van Houdt, Gregory Maes