Abstract: Disclosed herein are methods for prophylactic treatment of acute coronary syndrome (ACS) comprising administering, by inhalation, an effective amount of a pharmaceutical composition comprising at least one anticoagulant or antiplatelet agent to a subject in need thereof, wherein the anticoagulant or antiplatelet agent first enters the heart via the left atrium.

Abstract: Provided are methods of monitoring for a hemodynamically significant heart rhythm disturbance. The methods include obtaining baseline photoplethysmography (PPG) data from an individual, obtaining PPG signals from the individual during a monitoring period, comparing the PPG signals obtained during the monitoring period to the baseline PPG data, and producing an output when a hemodynamically significant heart rhythm disturbance is detected. In some aspects, the heart rhythm disturbance is detected based on a threshold reduction in PPG amplitude in the PPG signals obtained during the monitoring period compared to the baseline PPG data for a selected period of time; a threshold decreased slope in the initial positive deflection in PPG signals obtained during the monitoring period compared to the baseline PPG data for a selected number of consecutive beats; or both. Also provided are computer-readable media and computing devices that find use, e.g., in practicing the methods of the present disclosure.

Abstract: Disclosed herein are methods for prophylactic treatment of acute coronary syndrome (ACS) comprising administering, by inhalation, an effective amount of a pharmaceutical composition comprising at least one anticoagulant or antiplatelet agent to a subject in need thereof, wherein the anticoagulant or antiplatelet agent first enters the heart via the left atrium.

Abstract: Provided are methods of monitoring for a hemodynamically significant heart rhythm disturbance. The methods include obtaining baseline photoplethysmography (PPG) data from an individual, obtaining PPG signals from the individual during a monitoring period, comparing the PPG signals obtained during the monitoring period to the baseline PPG data, and producing an output when a hemodynamically significant heart rhythm disturbance is detected. In some aspects, the heart rhythm disturbance is detected based on a threshold reduction in PPG amplitude in the PPG signals obtained during the monitoring period compared to the baseline PPG data for a selected period of time; a threshold decreased slope in the initial positive deflection in PPG signals obtained during the monitoring period compared to the baseline PPG data for a selected number of consecutive beats; or both. Also provided are computer-readable media and computing devices that find use, e.g., in practicing the methods of the present disclosure.

Abstract: Disclosed herein are methods for prophylactic treatment of acute coronary syndrome (ACS) comprising administering, by inhalation, an effective amount of a pharmaceutical composition comprising at least one anticoagulant or antiplatelet agent to a subject in need thereof, wherein the anticoagulant or antiplatelet agent first enters the heart via the left atrium.

Abstract: Disclosed herein are methods for prophylactic treatment of acute coronary syndrome (ACS) comprising administering, by inhalation, an effective amount of a pharmaceutical composition comprising at least one anticoagulant or antiplatelet agent to a subject in need thereof, wherein the anticoagulant or antiplatelet agent first enters the heart via the left atrium.

Abstract: The invention relates to the selection of a collection of relevant single nucleotide polymorphisms across a genome to design a nucleic acid probe array. As such, the invention relates to diverse fields impacted by the nature of genetics, including biology, medicine, and medical diagnostics.

Abstract: The invention relates to the selection of a collection of relevant single nucleotide polymorphisms across a genome to design a nucleic acid probe array. As such, the invention relates to diverse fields impacted by the nature of genetics, including biology, medicine, and medical diagnostics.

Abstract: The invention relates to the selection of a collection of relevant single nucleotide polymorphisms across a genome to design a nucleic acid probe array. As such, the invention relates to diverse fields impacted by the nature of genetics, including biology, medicine, and medical diagnostics.

Abstract: Composite hybridization arrays and averaged hybridization arrays are provided. Composite hybridization arrays are formed from a user selected set of hybridization arrays, and once instantiated in a hybridization array database, are available for searching, analysis, and other data processing as with other types of hybridization arrays. This allows otherwise experiments using multiple different nucleotide microarrays to be efficiently consolidated and analyzed. Averaged hybridization arrays provided correctly averaged values from multiple user selected dual channel hybridization arrays.

Abstract: Composite hybridization arrays and averaged hybridization arrays are provided. Composite hybridization arrays are formed from a user selected set of hybridization arrays, and once instantiated in a hybridization array database, are available for searching, analysis, and other data processing as with other types of hybridization arrays. This allows otherwise experiments using multiple different nucleotide microarrays to be efficiently consolidated and analyzed. Averaged hybridization arrays provided correctly averaged values from multiple user selected dual channel hybridization arrays.