Abstract: Medical brassieres are shown and described. In one embodiment, the medical brassiere includes a first helical region and a second helical region, an adjuster, and a pair of opposing impact absorbent pads having an embedded silver infused antimicrobial and an arched lower end. Each of the helical regions include a reinforcing seam that is generally positioned along peripheral portions of the first helical region and second helical region. The medical brassiere is generally donned by a patient with an implanted medical device to provide comfort and protection against the device. In some examples, the brassiere includes a stretchable periphery assembly to provide freedom of movement, while providing uniform compression over a surgical site. The result is devices and methods to protect and comfort implanted devices, while providing an aesthetically-pleasing appearance.