Patents by Inventor Gregory McKenzie

Gregory McKenzie has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12605415
    Abstract: Disclosed herein are therapeutic compositions containing non-pathogenic, germination-competent bacterial spores, for the prevention, control, and treatment of gastrointestinal diseases, disorders and conditions and for general nutritional health.
    Type: Grant
    Filed: July 11, 2023
    Date of Patent: April 21, 2026
    Assignee: SERES THERAPEUTICS, INC.
    Inventors: Gregory McKenzie, Mary-Jane Lombardo McKenzie, David N. Cook, Marin Vulic, Geoffrey Von Maltzahn, Brian Goodman, John Grant Aunins, Matthew R. Henn, David Arthur Berry, Jonathan Winkler
  • Publication number: 20250268927
    Abstract: Provided herein are compositions, methods, strategies, kits, and articles of manufacture that are useful, inter alia, in the treatment or prevention of diseases, disorders, or conditions that may be associated with inflammation, infection, allergy, immune dysfunction, or dysbiosis of the intestinal microbiome, such as graft versus host disease (GVHD). In some aspects, the invention provides a synergistic combination of prebiotics that are synthetic or derived from human milk with a probiotic strain of bacterium, such as a strain capable of internalizing and consuming the prebiotic, e.g., Bifidobacterium longum subsp. infantis.
    Type: Application
    Filed: January 12, 2022
    Publication date: August 28, 2025
    Inventors: Gregory MCKENZIE, Scott ELSTER, Julie E. BUTTON
  • Patent number: 12364721
    Abstract: Provided herein are compositions, methods, strategies, kits, and articles of manufacture that are useful, inter alia, in the treatment or prevention of diseases or conditions such as those which may be associated with inflammation, infection, allergy, immune dysfunction, or dysbiosis of the intestinal microbiome. In some aspects, the invention provides a synergistic combination of a prebiotics, e.g., a mixture of human milk oligosaccharides, and a probiotic strain, such as a strain capable of internalizing and consuming the rebiotics, e.g., B. longum subsp. infantis.
    Type: Grant
    Filed: September 24, 2020
    Date of Patent: July 22, 2025
    Assignee: Prolacta Bioscience, Inc.
    Inventors: David N. Cook, Gregory McKenzie, Julie E. Button
  • Publication number: 20240216444
    Abstract: Compositions and methods of treating a gastrointestinal dysbiosis using a limited number of defined bacterial species are provided.
    Type: Application
    Filed: July 31, 2023
    Publication date: July 4, 2024
    Applicant: Seres Therapeutics, Inc.
    Inventors: Julie BUTTON, David COOK, Matthew HENN, Mary-Jane Lombardo MCKENZIE, Kevin LITCOFSKY, Asuncion MARTINEZ, Gregory MCKENZIE, Madhumitha NANDAKUMAR, Marin VULIC, Jennifer WORTMAN
  • Publication number: 20240173367
    Abstract: The invention provides compositions and methods for use in the treatment and prevention of cholestatic diseases.
    Type: Application
    Filed: May 17, 2023
    Publication date: May 30, 2024
    Applicant: Seres Therapeutics, Inc.
    Inventors: Madhumitha NANDAKUMAR, Alice Peiyu LIOU, Elizabeth Moritz HALVORSEN, Gregory MCKENZIE, Edward J. O'BRIEN, David COOK
  • Publication number: 20240139222
    Abstract: Provided herein are methods and compositions for increasing the safety and effectiveness of a bacteriotherapy. In some aspects, a mixture of prebiotics, e.g., human milk oligosaccharides, are administered to a subject who has or will undergo a bacteriotherapy. In certain aspects, the mixture of prebiotics is administered in combination with a probiotic capable of internalizing and/or consuming the prebiotics. Also provided are methods for preparing or identifying strains of bacteria suitable for a bacteriotherapy, such as by incubating a mixture of bacteria obtained from stool in the presence of one or more of agents, e.g., human milk oligosaccharides, capable of promoting the growth of beneficial bacteria.
    Type: Application
    Filed: August 13, 2021
    Publication date: May 2, 2024
    Inventors: Julie E. BUTTON, Gregory MCKENZIE, Scott ELSTER, Abigail REENS, Jessica PIERCE
  • Publication number: 20240050490
    Abstract: Disclosed herein are therapeutic compositions containing non-pathogenic, germination-competent bacterial spores, for the prevention, control, and treatment of gastrointestinal diseases, disorders and conditions and for general nutritional health.
    Type: Application
    Filed: July 11, 2023
    Publication date: February 15, 2024
    Applicant: Seres Therapeutics, Inc.
    Inventors: Gregory MCKENZIE, Mary-Jane LOMBARDO MCKENZIE, David N. COOK, Marin VULIC, Geoffrey VON MALTZAHN, Brian GOODMAN, John Grant AUNINS, Matthew R. HENN, David Arthur BERRY, Jonathan WINKLER
  • Patent number: 11730775
    Abstract: Disclosed herein are therapeutic compositions containing non-pathogenic, germination-competent bacterial spores, for the prevention, control, and treatment of gastrointestinal diseases, disorders and conditions and for general nutritional health.
    Type: Grant
    Filed: April 5, 2021
    Date of Patent: August 22, 2023
    Assignee: Seres Therapeutics, Inc.
    Inventors: Gregory McKenzie, Mary-Jane Lombardo McKenzie, David N. Cook, Marin Vulic, Geoffrey Von Maltzahn, Brian Goodman, John Grant Aunins, Matthew R. Henn, David Arthur Berry, Jonathan Winkler
  • Patent number: 11701394
    Abstract: The invention provides compositions and methods for use in the treatment and prevention of cholestatic diseases.
    Type: Grant
    Filed: August 14, 2018
    Date of Patent: July 18, 2023
    Assignee: Seres Therapeutics, Inc.
    Inventors: Madhumitha Nandakumar, Alice Peiyu Liou, Elizabeth Moritz Halvorsen, Gregory McKenzie, Edward J. O'Brien, David Cook
  • Publication number: 20230068960
    Abstract: Provided herein are compositions, methods, strategies, kits, and articles of manufacture that are useful, inter alia, in the treatment or prevention of diseases or conditions such as those which may be associated with inflammation, infection, allergy, immune dysfunction, or dysbiosis of the intestinal microbiome. In some aspects, the invention provides a synergistic combination of a prebiotics, e.g., a mixture of human milk oligosaccharides, and a probiotic strain, such as a strain capable of internalizing and consuming the rebiotics, e.g., B. longum subsp. infantis.
    Type: Application
    Filed: September 24, 2020
    Publication date: March 2, 2023
    Inventors: David N. COOK, Gregory MCKENZIE, Julie E. BUTTON
  • Publication number: 20230050728
    Abstract: There is provided a method of manufacturing silica microspheres includes the steps of mixing acid and water to form a mixture; adding a silicon alkoxide to the mixture so as to precipitate microspheres; allowing the microspheres to settle into a sediment and removing a supernatant liquid; and immersing the microspheres in acid.
    Type: Application
    Filed: October 5, 2021
    Publication date: February 16, 2023
    Inventors: Andrew RUYS, Gregory MCKENZIE, Ronald SLOCOMBE
  • Publication number: 20220249578
    Abstract: Compositions for methods of preventing or reducing pathogenic bacterial growth, proliferation, and/or colonization are described containing one or more types of non-pathogenic bacteria to be introduced into the gastrointestinal tract and effectively compete with pathogenic bacteria for monomeric or polymeric carbohydrate nutrients, and/or amino acid nutrients, and/or vitamin nutrients.
    Type: Application
    Filed: November 23, 2021
    Publication date: August 11, 2022
    Applicant: Seres Therapeutics, Inc.
    Inventors: David N. Cook, Han Zhang, Anthony Mario D'Onofrio, David Arthur Berry, Mary-Jane Lombardo McKenzie, John Grant Aunins, Gregory McKenzie, Toshiro K. Ohsumi
  • Patent number: 11185562
    Abstract: Compositions for methods of preventing or reducing pathogenic bacterial growth, proliferation, and/or colonization are described containing one or more types of non-pathogenic bacteria to be introduced into the gastrointestinal tract and effectively compete with pathogenic bacteria for monomeric or polymeric carbohydrate nutrients, and/or amino acid nutrients, and/or vitamin nutrients.
    Type: Grant
    Filed: February 4, 2014
    Date of Patent: November 30, 2021
    Assignee: Seres Therapeutics, Inc.
    Inventors: David N. Cook, Han Zhang, Anthony Mario D'Onofrio, David Arthur Berry, Mary-Jane Lombardo McKenzie, John Grant Aunins, Gregory McKenzie, Toshiro K. Ohsumi
  • Publication number: 20210244774
    Abstract: Disclosed herein are therapeutic compositions containing non-pathogenic, germination-competent bacterial spores, for the prevention, control, and treatment of gastrointestinal diseases, disorders and conditions and for general nutritional health.
    Type: Application
    Filed: April 5, 2021
    Publication date: August 12, 2021
    Applicant: Seres Therapeutics, Inc,
    Inventors: Gregory MCKENZIE, Mary-Jane LOMBARDO MCKENZIE, David N. COOK, Marin VULIC, Geoffrey VON MALTZAHN, Brian GOODMAN, John Grant AUNINS, Matthew R. HENN, David Arthur BERRY, Jonathan WINKLER
  • Patent number: 10967011
    Abstract: Disclosed herein are therapeutic compositions containing non-pathogenic, germination-competent bacterial spores, for the prevention, control, and treatment of gastrointestinal diseases, disorders and conditions and for general nutritional health.
    Type: Grant
    Filed: August 3, 2018
    Date of Patent: April 6, 2021
    Assignee: Seres Therapeutics, Inc.
    Inventors: Gregory McKenzie, Mary-Jane Lombardo McKenzie, David N. Cook, Marin Vulic, Geoffrey von Maltzahn, Brian Goodman, John Grant Aunins, Matthew R. Henn, David Arthur Berry, Jonathan Winkler
  • Publication number: 20210008128
    Abstract: The invention provides compositions and methods for use in the treatment and prevention of cholestatic diseases.
    Type: Application
    Filed: August 14, 2018
    Publication date: January 14, 2021
    Applicant: Seres Therapeutics, Inc.
    Inventors: Madhumitha NANDAKUMAR, Alice Peiyu LIOU, Elizabeth Moritz HALVORSEN, Gregory MCKENZIE, Edward J. O'BRIEN, David COOK
  • Publication number: 20190247447
    Abstract: Compositions and methods of treating a gastrointestinal dysbiosis using a limited number of defined bacterial species are provided.
    Type: Application
    Filed: November 23, 2016
    Publication date: August 15, 2019
    Inventors: Julie BUTTON, David COOK, Matthew HENN, Mary-Jane Lombardo MCKENZIE, Kevin LITCOFSKY, Asuncion MARTINEZ, Gregory MCKENZIE, Madhumitha NANDAKUMAR, Marin VULIC, Jennifer WORTMAN
  • Publication number: 20190099455
    Abstract: Disclosed herein are therapeutic compositions containing non-pathogenic, germination-competent bacterial spores, for the prevention, control, and treatment of gastrointestinal diseases, disorders and conditions and for general nutritional health.
    Type: Application
    Filed: August 3, 2018
    Publication date: April 4, 2019
    Inventors: Gregory McKenzie, Mary-Jane Lombardo McKenzie, David N. Cook, Marin Vulic, Geoffrey von Maltzahn, Brian Goodman, John Grant Aunins, Matthew R. Henn, David Arthur Berry, Jonathan Winkler
  • Patent number: 10064901
    Abstract: Disclosed herein are therapeutic compositions containing non-pathogenic, germination-competent bacterial spores, for the prevention, control, and treatment of gastrointestinal diseases, disorders and conditions and for general nutritional health.
    Type: Grant
    Filed: December 19, 2017
    Date of Patent: September 4, 2018
    Assignee: Seres Therapeutics, Inc.
    Inventors: Gregory McKenzie, Mary-Jane Lombardo McKenzie, David N. Cook, Marin Vulic, Geoffrey von Maltzahn, Brian Goodman, John Grant Aunins, Matthew R. Henn, David Arthur Berry, Jonathan Winkler
  • Publication number: 20180200310
    Abstract: Disclosed herein are therapeutic compositions containing non-pathogenic, germination-competent bacterial spores, for the prevention, control, and treatment of gastrointestinal diseases, disorders and conditions and for general nutritional health.
    Type: Application
    Filed: December 19, 2017
    Publication date: July 19, 2018
    Inventors: Gregory McKenzie, Mary-Jane Lombardo McKenzie, David N. Cook, Marin Vulic, Geoffrey von Maltzahn, Brian Goodman, John Grant Aunins, Matthew R. Henn, David Arthur Berry, Jonathan Winkler