Patents by Inventor Gregory P. Rouen

Gregory P. Rouen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Novel substituted succinic acid metallo-beta-lactamase inhibitors and their use in treating bacterial infections
    Publication number: 20030207859
    Abstract: This invention relates to novel substituted succinic acid metallo-&bgr;-lactamase inhibitors which are useful potentiators of &bgr;-lactam antibiotics.
    Type: Application
    Filed: January 9, 2003
    Publication date: November 6, 2003
    Inventors: James M. Balkovec, Mark L. Greenlee, Steven H. Olson, Gregory P. Rouen
  • Substituted succinic acid metallo-&bgr;-lactamase inhibitors and their use in treating bacterial infections
    Patent number: 6630510
    Abstract: This invention relates to novel substituted succinic acid metallo-&bgr;-lactamase inhibitors which are useful potentiators of &bgr;-lactam antibiotics. Accordingly, the present invention provides a method of treating bacterial infections in animals or humans which comprises administering, together with a b-lactam antibiotic, a therapeutically effective amount of a compound of formula I: including pharmaceutically acceptable salts, prodrugs, anhydrides, and solvates thereof.
    Type: Grant
    Filed: October 26, 2000
    Date of Patent: October 7, 2003
    Assignee: Merck & Co., Inc.
    Inventors: James M. Balkovec, Mark L. Greenlee, Steven H. Olson, Gregory P. Rouen
  • Novel substituted succinic acid metallo-beta-lactamase inhibitors and their use in treating bacterial infections
    Publication number: 20030078418
    Abstract: This invention relates to novel substituted succinic acid metallo-&bgr;-lactamase inhibitors which are useful potentiators of &bgr;-lactam antibiotics.
    Type: Application
    Filed: March 15, 2002
    Publication date: April 24, 2003
    Inventors: James M. Balkovec, Mark L. Greenlee, Steven H. Olson, Gregory P. Rouen