Abstract: Surgical instruments with articulatable surgical end effectors and rotary driven flexible drive members.

Abstract: Rapid and data-efficient training of an artificial intelligence (AI) algorithm are disclosed. Ground truth data are not available and a policy must be learned based on limited interactions with a system. A policy bank is used to explore different policies on a target system with shallow probing. A target policy is chosen by comparing a good policy from the shallow probing with a base target policy which has evolved over other learning experiences. The target policy then interacts with the target system and a replay buffer is built up. The base target policy is then updated using gradients found with respect to the transition experience stored in the replay buffer. The base target policy is quickly learned and is robust for application to new, unseen, systems.

Abstract: A clock generator circuit may include a multiplex circuit and a phase-locked loop circuit. The multiplex circuit may generate a reference clock signal for the phase-locked loop circuit by selecting one of different clock signals. In response to a switch of the reference clock signal from one clock signal to another, the phase-locked loop circuit may disable phase-locking and enter into a frequency acquisition mode during which the frequency of the phase-locked loop circuit's output clock signal is adjusted based on the frequency of the newly selected reference clock signal. After a period of time has elapsed, the phase-locked loop circuit returns to phase-locking operation.

Abstract: A customer return management system operates to categorize reverse items for resale, such as returned items or overstock inventory, and deliver the categorized items through a variety of different reverse supply chains in a way to increase a net recovery rate. The system uses a sortation system that performs a two-step process for sorting the reverse items into different reverse supply channels. In a first step, the items can be scanned and divided into two categories based on their value, such as high value items and low value items. The low value items can be quickly liquidated as a bulk. In a second step, high value items can be categorized into a number of different sorts, which are taken to different resale channels.

Abstract: A customer return management system operates to categorize reverse items for resale, such as returned items or overstock inventory, and deliver the categorized items through a variety of different reverse supply chains in a way to increase a net recovery rate. The system employs a two-step process for sorting the reverse items into different reverse supply channels. In a first step, the items can be scanned and divided into two categories based on their value, such as high value items and low value items. The low value items can be quickly liquidated as a bulk. The high value items can be categorized into a number of different sorts, which are taken to different resale channels.

Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for sorting items to final destinations in a storage facility. The system includes a first staging area configured to receive and stage the inbound items for routing throughout the storage facility; at least one conveyance system configured to route the staged items from the first staging area; a second staging area configured to receive and sort the items based on geographic information along the first path of the conveyance system; an outbound delivery area configured to receive and dispatch the sorted items into one or more delivery vehicles associated with the storage facility; a local delivery staging area configured to receive a second portion of the staged items along a second path of the at least one conveyance system; and a local delivery outbound area configured to receive the sorted items from the local delivery staging area.

Abstract: Provided herein are methods of treating a cancer comprising a KRAS G12C mutation in a patient with active brain metastases, comprising administering sotorasib to the patient in amount effective to treat the cancer.

Abstract: Transfer learning based on prediction determines a similarity between a source base station and a target base station. Importance of parameters is determined and training is adjusted to respect the importance of parameters. A lack of historical data is compensated by selecting a base station as source base station which has a larger amount of historical data.

Abstract: A network accessible context store holds a plurality of different context items. Each context item includes one or more context-describing values. An arbitration engine resolves conflicting requests to assign different context-describing values to a context item held in the network-accessible context store.

Abstract: A context store holding one or more context items is accessible by one or more domain interpreters. Each context item includes a unique identifier and one or more context-describing values. The domain interpreters include context providers for loading a context item with context-describing values and/or context consumers for taking context-describing values from a context item.

Abstract: An auxiliary device communicates with a user in a manner other than a conventional, textual visual representation. For example, auxiliary device(s) can provide information aurally, vocally, visually (non-textual), tactilely and/or olfactorily. The information communicated can include alternative information to information displayed on a primary display of the computer system. A platform component of a computer system can provide device-specific and/or device-independent information to the auxiliary device.

Abstract: A context store holding one or more context items is accessible by one or more domain interpreters. Each context item includes a unique identifier and one or more context-describing values. The domain interpreters include context providers for loading a context item with context-describing values and/or context consumers for taking context-describing values from a context item.

Abstract: A sensor application programming interface (API) is capable of restricting an application's access to sensor data measured by a sensor, while at the same time providing access to sensor properties of the sensor, even if access has not been granted to the application for the sensor.

Abstract: A system for generating a document at a remote printer includes a print services server, an application server, and a print control executable. The print services server stores a plurality of binary objects each in association with a unique identifier. Each binary object includes a print formatted object representing a document set. The application server: i) establishes a transport session with a browser of a remote client; ii) provides a listing of a plurality of document sets to the remote client; iii) obtains identification of a selected one of the plurality of document sets; and iv) generates a return object instruction message to the print services sever. The return object instruction message including an identification number which corresponds to the unique identifier associated with the binary object that includes the print formatted object representing the selected one of the plurality of document sets. The print services server receives the return object instruction and provides a response.

Abstract: A system for generating a document at a print system under the control of a remote client comprises a document image template, a print command object, and a print control executable. The document template comprising a document image and a plurality of data fields. The print command object receives a content message which comprises a plurality of data elements. The print command object creates a binary object representing a print command file. The print command file includes data and print system commands representing the document image template with the data fields populated with data elements from the content message. The binary object is provided to the remote client. The print control executable, operating on the remote client, receives the binary object into volatile memory send passes the print command file to the print system for document generation.

Abstract: A system for interfacing with an application server and generating a print command file for secure download and printing of a document at a remote client comprises image template storage, binary object storage, a print command object, and a return object. A plurality of document templates are stored in the image template storage. Each document template comprises a document pattern and a plurality of data fields. The print command object: i) receives a content message from the application server, the content message comprising a plurality of data elements; ii) creates a print command file which includes data and print system commands representing a document image template with its data fields populated with data elements from the content message; iii) stores a representation of the print command file, in conjunction with a unique identification number, in the binary object storage; and iv) returns the unique identification number to the application server.

Abstract: The present invention relates to a secure check clearing server. The check clearing server comprises a database for storing payment information associated with an issued check and a status indicator associated with the issued check. A clearing module receiving a clearing request message. The clearing request message includes payment information associated with a purported check. The payment information includes a core digital image of the purported check. The clearing module determines whether the purported check is unaltered and clearable and, if unaltered and clearable initiates clearing of the purported check. The purported check is determined to be unaltered if the payment information associated with the purported check matches the payment information associated with the issued check. The purported check is determined to be clearable if the issued check is not cleared or canceled.

Abstract: An electronic bill presentment and payment system for presenting an invoice of a vendor to a customer comprises a billing database for storing an invoice file. The invoice file comprises a line value representing an amount payable by the customer for a product provided by the vendor, a tax value representing an amount payable as a tax on the product, and a fee value representing an amount payable as a fee on the product. An application server provides for receiving a request to adjust the line value from the customer, providing instructions to replace the line value with an adjusted line value, calculating an adjusted tax value and an adjusted fee value based on the adjusted line value, and providing instructions to replace the tax value with the adjusted tax value. Where appropriate, flat fee adjustments are also made.

Abstract: An electronic bill presentment and payment system for presenting an invoice of a vendor to a customer comprises a billing database for storing an invoice file. The invoice file comprises a line value representing an amount payable by the customer for a product provided by the vendor, a tax value representing an amount payable as a tax on the product, and a fee value representing an amount payable as a fee on the product. An application server provides for receiving a request to adjust the line value from the customer, providing instructions to replace the line value with an adjusted line value, calculating an adjusted tax value and an adjusted fee value based on the adjusted line value, and providing instructions to replace the tax value with the adjusted tax value.

Abstract: A composition, a process for producing the composition, and a process for producing a nitrile are disclosed. The composition is substantially anhydrous or free of water and comprises ammonia and an anti-foaming agent. The composition can be produced by contacting substantially anhydrous ammonia with an anti-foaming amount of an anti-foaming agent. The process for producing a nitrile comprises contacting a hydrocarbon with the composition disclosed herein.