Patents by Inventor Gregory Polites

Gregory Polites has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

Mouse unable to express functional alpha-4 integrin protein, and methods for assaying compounds or agents for alpha-4 integrin protein antagonist activity and a genetic marker for evaluating efficacy of modulators of signaling activity of a VLA-4 receptor

Publication number: 20030154499

Abstract: Provided herein is a mouse that is unable to express functional alpha-4 integrin protein, and methods for assaying agents for alpha-4 integrin antagonist activity, as well genetic markers for analyzing the efficacy of VLA-4 modulators, and particularly antagonists.

Type: Application

Filed: June 5, 2002

Publication date: August 14, 2003

Inventors: Monika Wasel-Nielen, Bernhard Kirschbaum, Martyn Foster, Gregory Polites, Olga Khorkova, Bin Zhu

Mouse unable to express functional alpha-4 integrin protein, and methods for assaying compounds or agents for alpha-4 integrin protein antagonist activity and a genetic marker for evaluating efficacy of modulators of signaling activity of a VLA-4 receptor