Abstract: An applicator and method for applying a microneedle array to skin. The applicator can include a body having a first portion and a second portion defining a cavity, the second portion having a slot presented on an outside surface for insertion of the microneedle array into the cavity. The first portion and the second portion are slidable relative to one other along an axis enabling the body to be in an unprimed configuration and a primed configuration. The applicator further includes a door operable with the second portion, the door being movable from a first door position to a second door position, wherein when the device is in the unprimed configuration, the door at least partially obstructs the slot and access into the cavity. When the device is in the primed configuration, the door does not obstruct the slots and enables access into the cavity.

Abstract: A microarray carrier (200) for use with a microarray applicator (100) is provided. The microarray carrier (200) includes a body (202) defining a cavity (210). The microarray carrier (200) also includes a plurality of tabs (220, 222, 224, 226) disposed on the body (202) and extending into the cavity (210). Each of the plurality of tabs (220, 222, 224, 226) defines a contour line along a length thereof extending from a proximal end of the tab adjacent the body to a support surface (228, 230, 232, 234) spaced apart from the body. The support surface (228, 230, 232, 234) is inclined with respect to the contour line where the contour line intersects the support surface (228, 230, 232, 234). A projected area of each of the plurality of tabs (220, 222, 224, 226) onto a horizontal plane (HP) of the cavity (210) is greater than an area of the support surface (228, 230, 232, 234). The support surface (228, 230, 232, 234) is aligned non-perpendicular to the horizontal plane (HP).

Abstract: An applicator and method for applying a microneedle array to skin. The applicator can include a body having a first portion and a second portion defining a cavity, the second portion having a slot presented on an outside surface for insertion of the microneedle array into the cavity. The first portion and the second portion are slidable relative to one other along an axis enabling the body to be in an unprimed configuration and a primed configuration. The applicator further includes a door operable with the second portion, the door being movable from a first door position to a second door position, wherein when the device is in the unprimed configuration, the door at least partially obstructs the slot and access into the cavity. When the device is in the primed configuration, the door does not obstruct the slots and enables access into the cavity.

Abstract: A lead having an extendable and retractable fixation mechanism has a rotating terminal pin at the terminal end which rotates the fixation mechanism at the distal end. As the terminal pin is rotated, the fixation mechanism is extended or retracted from the distal end of the lead. A threaded collar allows for the fixation mechanism to smoothly extend and retract from the lead, and allows for a 1:1 turn ratio between the terminal pin and the fixation mechanism. A fluoroscopic ring disposed at the distal end of the lead provides information during the implantation process.

Abstract: An apparatus includes an elongated tube and an elongated rod having a holding member on one end, the holding member is adapted to hold an end of a lead such that the end of the lead can be pulled through the elongated tube resulting in minimal forces on the lead.

Abstract: A lead assembly and method of forming a lead assembly is provided. Devices and methods of forming the lead assembly include a support coil. The support coil provides enhanced support and protection from lead damage and failure. A lead assembly and method of forming a lead assembly is also provided including at least one electrode. Electrodes may be incorporated into the support coil design. The lead assembly and method of forming a lead assembly may be incorporated with other medical devices such as an implantable defibrillator.

Abstract: A lead having an extendable and retractable fixation mechanism has a rotating terminal pin at the terminal end which rotates the fixation mechanism at the distal end. As the terminal pin is rotated, the fixation mechanism is extended or retracted from the distal end of the lead. A threaded collar allows for the fixation mechanism to smoothly extend and retract from the lead, and allows for a 1:1 turn ratio between the terminal pin and the fixation mechanism. A fluoroscopic ring disposed at the distal end of the lead provides information during the implantation process.

Abstract: A lead having an extendable and retractable fixation mechanism has a rotating terminal pin at the terminal end which rotates the fixation mechanism at the distal end. As the terminal pin is rotated, the fixation mechanism is extended or retracted from the distal end of the lead. A threaded collar allows for the fixation mechanism to smoothly extend and retract from the lead, and allows for a 1:1 turn ratio between the terminal pin and the fixation mechanism. A fluoroscopic ring disposed at the distal end of the lead provides information during the implantation process.

Abstract: A connector for connecting to an energy source such as a pulse generator for a cardiac stimulator system. The connector assembly includes a pin, at least one ring and a sleeve composed of an insulative hard polymer molded between the pin and ring such that the sleeve provides electrical insulation between the pin and ring and mechanically couples the pin and ring.

Abstract: An apparatus includes an elongated tube and an elongated rod having a holding member on one end, the holding member is adapted to hold an end of a lead such that the end of the lead can be pulled through the elongated tube resulting in minimal forces on the lead.

Abstract: A helical element for insertion into tissue comprises a helical element having an insertion end, a protruding end and an open central area within the wire, rods, filaments, cables or the like that form the helix. The helical element has at least its insertion end covered by a cap of a water-soluble or water-dispersible composition. The cap is provided with a surface shape in a cross-section in which surface variations are present in the cross-section which create a surface orientation where a line from the center of the cross-section can intersect the surface, and a line perpendicular to said radius at a point of intersection with said surface forms four quadrants, three of said quadrants containing water-soluble or water-dispersible cap material. There is either a hollow area within the composition within the open central area or the material is more porous than the remaining material.

Abstract: A lead includes a lead body extending from a distal end to a proximal end, and at least one conductor disposed within the lead body and extending from the distal end to the proximal end of the lead body. The lead further includes an outer terminal ring, a terminal pin, and an insulative sleeve disposed between the outer terminal ring and the terminal pin, where the insulative sleeve is coupled with the outer terminal ring with a snap-fit connection. A pin latch is disposed on an outer periphery surface of the insulative sleeve, where the pin latch is rotatable about a hinge point.

Abstract: A lead having an extendable and retractable fixation mechanism has a rotating terminal pin at the terminal end which rotates the fixation mechanism at the distal end. As the terminal pin is rotated, the fixation mechanism is extended or retracted from the distal end of the lead. A threaded collar allows for the fixation mechanism to smoothly extend and retract from the lead, and allows for a 1:1 turn ratio between the terminal pin and the fixation mechanism. A fluoroscopic ring disposed at the distal end of the lead provides information during the implantation process.

Abstract: A connector assembly of an electrophysiologial device. The connector assembly includes a substrate forming a tube extending from a proximal end to a distal end an electrical circuit formed on the substrate, such as etching or printing, where the substrate is optionally non-conductive. In another option, the connector assembly includes clad wires and/or flexible circuits within an insulated terminal structure.

Abstract: A connector for connecting to an energy source such as a pulse generator for a cardiac stimulator system. The connector assembly includes a pin, at least one ring and a sleeve composed of an insulative hard polymer molded between the pin and ring such that the sleeve provides electrical insulation between the pin and ring and mechanically couples the pin and ring.

Abstract: An apparatus includes an elongated tube and an elongated rod having a holding member on one end, the holding member is adapted to hold an end of a lead such that the end of the lead can be pulled through the elongated tube resulting in minimal forces on the lead.

Abstract: A connector for connecting to an energy source such as a pulse generator for a cardiac stimulator system. The connector assembly includes a pin, at least one ring and a sleeve composed of an insulative hard polymer molded between the pin and ring such that the sleeve provides electrical insulation between the pin and ring and mechanically couples the pin and ring.

Abstract: A hemostasis valve for use in introducing an over-the-wire medical lead into a patient's vascular system comprises a housing with a passageway, the passageway including an elastomeric pierceable seal member interposed therein and a resilient, annular tip surrounding a distal end of the housing where the tip has a central opening that is sized to receive a tubular connector terminal at the proximal end of the medical lead for dripping the end of the lead and sealing the lead's tubular connector terminal in the passageway of the housing.

Abstract: A lead assembly and method of forming a lead assembly is provided. Devices and methods of forming the lead assembly include a support coil. The support coil provides enhanced support and protection from lead damage and failure. A lead assembly and method of forming a lead assembly is also provided including at least one electrode. Electrodes may be incorporated into the support coil design. The lead assembly and method of forming a lead assembly may be incorporated with other medical devices such as an implantable defibrillator.

Abstract: A hemostasis valve for use in introducing an over-the-wire medical lead into a patient's vascular system comprises a housing with a passageway, the passageway including an elastomeric pierceable seal member interposed therein and a resilient, annular tip surrounding a distal end of the housing where the tip has a central opening that is sized to receive a tubular connector terminal at the proximal end of the medical lead for dripping the end of the lead and sealing the lead's tubular connector terminal in the passageway of the housing.