Abstract: Digital microfluidic (DMF) methods and apparatuses (including devices, systems, cartridges, DMF readers, etc.), and in particular DMF apparatuses and methods adapted for large volume. For example, described herein are methods and apparatuses for DMF using an air gap having a width of the gap that may be between 0.3 mm and 3 mm. Also described herein are DMF readers for use with a DMF cartridges, including those adapted for use with large air gap/large volume, although smaller volumes may be used as well.

Abstract: Digital microfluidic (DMF) methods and apparatuses (including devices, systems, cartridges, DMF readers, etc.), and in particular DMF apparatuses and methods adapted for large volume. For example, described herein are methods and apparatuses for DMF using an air gap having a width of the gap that may be between 0.3 mm and 3 mm. Also described herein are DMF readers for use with a DMF cartridges, including those adapted for use with large air gap/large volume, although smaller volumes may be used as well.

Abstract: Digital microfluidic (DMF) methods and apparatuses (including devices, systems, cartridges, DMF readers, etc.), and in particular DMF apparatuses and methods adapted for large volume. For example, described herein are methods and apparatuses for DMF using an air gap having a width of the gap that may be between 0.3 mm and 3 mm. Also described herein are DMF readers for use with a DMF cartridges, including those adapted for use with large air gap/large volume, although smaller volumes may be used as well.

Abstract: Digital microfluidic (DMF) methods and apparatuses (including devices, systems, cartridges, DMF readers, etc.), and in particular DMF apparatuses and methods adapted for large volume. For example, described herein are methods and apparatuses for DMF using an air gap having a width of the gap that may be between 0.3 mm and 3 mm. Also described herein are DMF readers for use with a DMF cartridges, including those adapted for use with large air gap/large volume, although smaller volumes may be used as well.

Abstract: The present disclosure is directed to an electrochemical cell connector for electrically connecting a plurality of electrochemical cells, and to battery packs including the electrochemical cell connector. The electrochemical cell connectors of the present disclosure are fabricated from a flexible circuit. The flexible circuit includes conductors, such as nickel conductors, soldered or otherwise attached thereto via holes or openings in the flexible circuit. These conductors may be welded or otherwise attached to an electrochemical cell, and the electrochemical cell connections made on the flexible circuit. In many embodiments, the conductors may be attached to the flexible circuit using industry standard automated assembly equipment thus streamlining the manufacturing process and improving overall quality of the product.

Abstract: The present disclosure is directed to an electrochemical cell connector for electrically connecting a plurality of electrochemical cells, and to battery packs including the electrochemical cell connector. The electrochemical cell connectors of the present disclosure are fabricated from a flexible circuit. The flexible circuit includes conductors, such as nickel conductors, soldered or otherwise attached thereto via holes or openings in the flexible circuit. These conductors may be welded or otherwise attached to an electrochemical cell, and the electrochemical cell connections made on the flexible circuit. In many embodiments, the conductors may be attached to the flexible circuit using industry standard automated assembly equipment thus streamlining the manufacturing process and improving overall quality of the product.

Abstract: Digital microfluidic (DMF) methods and apparatuses (including devices, systems, cartridges, DMF readers, etc.), and in particular DMF apparatuses and methods adapted for large volume. For example, described herein are methods and apparatuses for DMF using an air gap having a width of the gap that may be between 0.3 mm and 3 mm. Also described herein are DMF readers for use with a DMF cartridges, including those adapted for use with large air gap/large volume, although smaller volumes may be used as well.

Abstract: Bifunctional molecules and methods for their use in the production of binary complexes in a host are provided. The bifunctional molecule is a conjugate of a drug moiety and a presenter protein ligand. In the subject methods, an effective amount of the bifunctional molecule is administered to the host. The bifunctional molecule binds to the presenter protein to produce a binary complex that exhibits at least one of improved affinity, specificity or selectivity as compared to the corresponding free drug. The subject methods and compositions find use in a variety of therapeutic applications.