Patents by Inventor Gregory Roger Martin
Gregory Roger Martin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9290730Abstract: A multilayered cell culture apparatus for the culturing of cells is disclosed. The cell culture apparatus is defined as an integral structure having a plurality of cell culture chambers in combination with tracheal space(s). The body of the apparatus has imparted therein gas permeable membranes in combination with tracheal spaces that will allow the free flow of gases between the cell culture chambers and the external environment. The flask body also includes an aperture that will allow access to the cell growth chambers by means of a needle or cannula. The size of the apparatus, and location of an optional neck and cap section, allows for its manipulation by standard automated assay equipment, further making the apparatus ideal for high throughput applications.Type: GrantFiled: April 16, 2014Date of Patent: March 22, 2016Assignee: Corning IncorporatedInventors: Gregory Roger Martin, Allison Jean Tanner
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Publication number: 20150361388Abstract: An apparatus (100) for cell release from a cell culture article (101), including: an ultrasonic source (105); a stage comprising a base (112) and a raised portion (114) that defines a cell culture article confinement area; and a mechanism for relative scan motion between the ultrasonic source and the cell culture article confined to the stage. Also disclosed is a method for cell release and harvesting from a cell culture article (101), including: securing a cell culture article in the disclosed cell release apparatus; and accomplishing relative motion scanning between the energized ultrasonic source and the cell culture article for a time, as defined herein.Type: ApplicationFiled: February 26, 2014Publication date: December 17, 2015Inventors: Gregory Roger Martin, Allison Jean Tanner
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Publication number: 20150337252Abstract: A multilayered cell culture apparatus for the culturing of cells is disclosed. The cell culture apparatus is defined as an integral structure having a plurality of cell culture chambers in combination with tracheal space(s). The body of the apparatus has imparted therein gas permeable membranes in combination with tracheal spaces that will allow the free flow of gases between the cell culture chambers and the external environment. The flask body also includes an aperture that will allow access to the cell growth chambers by means of a needle or cannula. The size of the apparatus, and location of an optional neck and cap section, allows for its manipulation by standard automated assay equipment, further making the apparatus ideal for high throughput applications.Type: ApplicationFiled: July 30, 2015Publication date: November 26, 2015Inventors: Gregory Roger MARTIN, Allison Jean TANNER
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Publication number: 20150329813Abstract: A multilayered cell culture apparatus for the culturing of cells is disclosed. The cell culture apparatus is defined as an integral structure having a plurality of cell culture chambers in combination with tracheal space(s). The body of the apparatus has imparted therein gas permeable membranes in combination with tracheal spaces that will allow the free flow of gases between the cell culture chambers and the external environment. The flask body also includes an aperture that will allow access to the cell growth chambers by means of a needle or cannula. The size of the apparatus, and location of an optional neck and cap section, allows for its manipulation by standard automated assay equipment, further making the apparatus ideal for high throughput applications.Type: ApplicationFiled: July 29, 2015Publication date: November 19, 2015Inventors: Gregory Roger MARTIN, Allison Jean TANNER
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Publication number: 20150275167Abstract: An ex vivo cell culture sustained release composition, including: a mixture comprising: a sustenant; and a non-biodegradable binder; and a non-biodegradable and water insoluble encapsulant coat that encapsulates the mixture, as defined herein. Also disclosed is a method for sustainably providing a sustenant to a cell culture in aqueous media, including contacting a cell culture with the sustained release composition.Type: ApplicationFiled: March 20, 2015Publication date: October 1, 2015Inventors: Ronald Allen Faris, Ann MeeJin Ferrie, Vasiliy Nikolaevich Goral, Gregory Roger Martin, Jin Liu
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Publication number: 20150232796Abstract: A multilayered cell culture apparatus for the culturing of cells is disclosed. The cell culture apparatus is defined as an integral structure having a plurality of cell culture chambers in combination with tracheal space(s). The body of the apparatus has imparted therein gas permeable membranes in combination with tracheal spaces that will allow the free flow of gases between the cell culture chambers and the external environment. The flask body also includes an aperture that will allow access to the cell growth chambers by means of a needle or cannula. The size of the apparatus, and location of an optional neck and cap section, allows for its manipulation by standard automated assay equipment, further making the apparatus ideal for high throughput applications.Type: ApplicationFiled: April 29, 2015Publication date: August 20, 2015Inventors: Gregory Roger Martin, Allison Jean Tanner
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Patent number: 9045721Abstract: A multilayered cell culture apparatus for the culturing of cells is disclosed. The cell culture apparatus is defined as an integral structure having a plurality of cell culture chambers in combination with tracheal space(s). The body of the apparatus has imparted therein gas permeable membranes in combination with tracheal spaces that will allow the free flow of gases between the cell culture chambers and the external environment. The flask body also includes an aperture that will allow access to the cell growth chambers by means of a needle or cannula. The size of the apparatus, and location of an optional neck and cap section, allows for its manipulation by standard automated assay equipment, further making the apparatus ideal for high throughput applications.Type: GrantFiled: December 18, 2013Date of Patent: June 2, 2015Assignee: Corning IncorporatedInventors: Gregory Roger Martin, Allison Jean Tanner
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Patent number: 9040290Abstract: A multilayered cell culture apparatus for the culturing of cells is disclosed. The cell culture apparatus is defined as an integral structure having a plurality of cell culture chambers in combination with tracheal space(s). The body of the apparatus has imparted therein gas permeable membranes in combination with tracheal spaces that will allow the free flow of gases between the cell culture chambers and the external environment. The flask body also includes an aperture that will allow access to the cell growth chambers by means of a needle or cannula. The size of the apparatus, and location of an optional neck and cap section, allows for its manipulation by standard automated assay equipment, further making the apparatus ideal for high throughput applications.Type: GrantFiled: November 8, 2013Date of Patent: May 26, 2015Assignee: Corning IncorporatedInventors: Gregory Roger Martin, Allison Jean Tanner
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Publication number: 20150048085Abstract: An article including, either: a frame having an interior cavity, and a flexible liner situated within the interior cavity; or a deformable frame having an interior cavity, as defined herein. Either frame can receive a sample, such as liquid having suspended live cells, and cooling freezes the sample to a solid sample. The solid sample can be readily ejected from the article having either a frame with the flexible liner, or the deformable frame, without extensive thawing. The solid sample can be rapidly displaced from the article by the methods and apparatus disclosed herein.Type: ApplicationFiled: November 15, 2013Publication date: February 19, 2015Applicant: CORNING INCORPORATEDInventors: Jessica Monique Brown, Nicholas Michael Illsley, Gregory Roger Martin, Ana Maria del Pilar Pardo, Allison Jean Tanner
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Publication number: 20150017711Abstract: An integrated cell culture system may include one or more cell culture vessels, manipulation apparatus, pumping apparatus, cell release apparatus, monitoring apparatus, and a control apparatus. The control apparatus may be used to monitor and control the system to facilitate effective cell culturing. The cell release apparatus may be used to release a plurality of cells adhered to the cell culture surfaces of the cell culture vessels.Type: ApplicationFiled: January 31, 2013Publication date: January 15, 2015Inventors: Scott Matthew Bennett, David Alan Kenney, Gregory Roger Martin, Allison Jean Tanner
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Patent number: 8927267Abstract: The present invention relates generally to a multi-layer system for containing cells in culture, and a system for visualizing cells cultured in the multi-layered system. More specifically, the present invention relates to a multi-layer cell culture device having a specialized bottom plate and a microscope adaptor which can accommodate a microscope to allow microscopic visualization of cells cultured in the device.Type: GrantFiled: September 19, 2011Date of Patent: January 6, 2015Assignee: Corning IncorporatedInventors: Scott Matthew Bennett, David Alan Kenney, Gregory Roger Martin, Jeffry J Santman, Allison Jean Tanner
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Publication number: 20140322806Abstract: A spheroid cell culture article including: a frame having a chamber including: an opaque side wall surface; a top aperture; a gas-permeable, transparent bottom; and optionally a chamber annex surface and second bottom, and at least a portion of the transparent bottom includes at least one concave arcuate surface, is disclosed. Methods of making and using the article are also disclosed.Type: ApplicationFiled: November 22, 2013Publication date: October 30, 2014Applicant: Corning IncorporatedInventors: Scott Matthew Bennett, Brian Robb Douglass, Paul Ernest Gagnon, JR., Gregory Roger Martin, Paul Michael Szlosek, Allison Jean Tanner
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Patent number: 8846399Abstract: A multilayered cell culture apparatus for the culturing of cells is disclosed. The cell culture apparatus is defined as an integral structure having a plurality of cell culture chambers in combination with tracheal space(s). The body of the apparatus has imparted therein gas permeable membranes in combination with tracheal spaces that will allow the free flow of gases between the cell culture chambers and the external environment. The flask body also includes an aperture that will allow access to the cell growth chambers by means of a needle or cannula. The size of the apparatus, and location of an optional neck and cap section, allows for its manipulation by standard automated assay equipment, further making the apparatus ideal for high throughput applications.Type: GrantFiled: May 29, 2013Date of Patent: September 30, 2014Assignee: Corning IncorporatedInventors: Gregory Roger Martin, Allison Jean Tanner
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Publication number: 20140227775Abstract: A multilayered cell culture apparatus for the culturing of cells is disclosed. The cell culture apparatus is defined as an integral structure having a plurality of cell culture chambers in combination with tracheal space(s). The body of the apparatus has imparted therein gas permeable membranes in combination with tracheal spaces that will allow the free flow of gases between the cell culture chambers and the external environment. The flask body also includes an aperture that will allow access to the cell growth chambers by means of a needle or cannula. The size of the apparatus, and location of an optional neck and cap section, allows for its manipulation by standard automated assay equipment, further making the apparatus ideal for high throughput applications.Type: ApplicationFiled: April 16, 2014Publication date: August 14, 2014Applicant: CORNING INCORPORATEDInventors: GREGORY ROGER MARTIN, Allison Jean Tanner
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Publication number: 20140106444Abstract: A multilayered cell culture apparatus for the culturing of cells is disclosed. The cell culture apparatus is defined as an integral structure having a plurality of cell culture chambers in combination with tracheal space(s). The body of the apparatus has imparted therein gas permeable membranes in combination with tracheal spaces that will allow the free flow of gases between the cell culture chambers and the external environment. The flask body also includes an aperture that will allow access to the cell growth chambers by means of a needle or cannula. The size of the apparatus, and location of an optional neck and cap section, allows for its manipulation by standard automated assay equipment, further making the apparatus ideal for high throughput applications.Type: ApplicationFiled: December 18, 2013Publication date: April 17, 2014Applicant: CORNING INCORPORATEDInventors: Gregory Roger Martin, Allison Jean Tanner
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Publication number: 20140065709Abstract: A multilayered cell culture apparatus for the culturing of cells is disclosed. The cell culture apparatus is defined as an integral structure having a plurality of cell culture chambers in combination with tracheal space(s). The body of the apparatus has imparted therein gas permeable membranes in combination with tracheal spaces that will allow the free flow of gases between the cell culture chambers and the external environment. The flask body also includes an aperture that will allow access to the cell growth chambers by means of a needle or cannula. The size of the apparatus, and location of an optional neck and cap section, allows for its manipulation by standard automated assay equipment, further making the apparatus ideal for high throughput applications.Type: ApplicationFiled: November 8, 2013Publication date: March 6, 2014Applicant: Corning IncorporatedInventors: GREGORY ROGER MARTIN, Allison Jean Tanner
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Publication number: 20130260454Abstract: A multilayered cell culture apparatus for the culturing of cells is disclosed. The cell culture apparatus is defined as an integral structure having a plurality of cell culture chambers in combination with tracheal space(s). The body of the apparatus has imparted therein gas permeable membranes in combination with tracheal spaces that will allow the free flow of gases between the cell culture chambers and the external environment. The flask body also includes an aperture that will allow access to the cell growth chambers by means of a needle or cannula. The size of the apparatus, and location of an optional neck and cap section, allows for its manipulation by standard automated assay equipment, further making the apparatus ideal for high throughput applications.Type: ApplicationFiled: May 29, 2013Publication date: October 3, 2013Applicant: Corning IncorporatedInventors: Gregory Roger Martin, Allison Jean Tanner
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Patent number: 8177082Abstract: An assembly for culturing cells includes a housing defining a reservoir for containing cell culture media and an opening in fluid communication with the reservoir. The cell culture assembly further includes a filter valve assembly configured to sealingly engage the opening. The filter valve assembly includes a flexible membrane, a contiguous side wall, an end wall, and a microbial filter. The end wall has an opening and extends across one end of the side wall to form a major cavity within the side wall and the end wall. The flexible membrane has a slit spanning the membrane and is disposable within the major cavity such that the membrane sealingly divides the major cavity into (i) a chamber formed between the end wall and the membrane and (ii) a minor cavity formed by the membrane and a portion of the side wall. The minor cavity is in fluid communication with the reservoir.Type: GrantFiled: April 18, 2008Date of Patent: May 15, 2012Assignee: Corning IncorporatedInventors: Henry Joseph Cattadoris, Gregory Roger Martin, Allison Jean Tanner
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Publication number: 20120070887Abstract: The present invention relates generally to a multi-layer system for containing cells in culture, and a system for visualizing cells cultured in the multi-layered system. More specifically, the present invention relates to a multi-layer cell culture device having a specialized bottom plate and a microscope adaptor which can accommodate a microscope to allow microscopic visualization of cells cultured in the device.Type: ApplicationFiled: September 19, 2011Publication date: March 22, 2012Inventors: Scott Mathew Bennett, David Alan Kenney, Gregory Roger Martin, Jeffrey J. Santman, Allison Jean Tanner
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Patent number: 8114646Abstract: The present invention provides a method for treating cell culture vessels including multi-layer cell culture vessels with ultrasonic energy to dissociate cells growing on surfaces of cell culture vessels.Type: GrantFiled: May 19, 2009Date of Patent: February 14, 2012Assignee: Corning IncorporatedInventors: Gregory Roger Martin, Allison Jean Tanner