Patents by Inventor Gregory S. Blank

Gregory S. Blank has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Protein purification
    Patent number: 6797814
    Abstract: A method for purifying proteins by Protein A chromatography is described which comprises the steps of: (a) adsorbing the protein to Protein A immobilized on a solid phase comprising silica or glass; (b) removing contaminants bound to the solid phase by washing the solid phase with a hydrophobic electrolyte solvent; and (c) recovering the protein from the solid phase.
    Type: Grant
    Filed: September 26, 2001
    Date of Patent: September 28, 2004
    Assignee: Genentech, Inc.
    Inventor: Gregory S. Blank
  • Protein recovery
    Publication number: 20040138426
    Abstract: The invention herein provides a method for recovering a polypeptide comprising exposing a composition comprising a polypeptide to a reagent which binds to, or modifies, the polypeptide, wherein the reagent is immobilized on a solid phase; and then passing the composition through a filter bearing a charge which is opposite to the charge of the reagent in the composition, so as to remove leached reagent from the composition.
    Type: Application
    Filed: January 21, 2004
    Publication date: July 15, 2004
    Applicant: Genentech, Inc.
    Inventors: Gregory S. Blank, Daljit S. Narindray, Gerardo A. Zapata
  • Protein purification
    Publication number: 20040106180
    Abstract: A method for purifying proteins by Protein A chromatography is described which comprises the steps of: (a) adsorbing the protein to Protein A immobilized on a solid phase comprising silica or glass; (b) removing contaminants bound to the solid phase by washing the solid phase with a hydrophobic electrolyte solvent; and (c) recovering the protein from the solid phase.
    Type: Application
    Filed: November 21, 2003
    Publication date: June 3, 2004
    Applicant: Genentech, Inc.
    Inventor: Gregory S. Blank
  • Protein recovery
    Patent number: 6716598
    Abstract: The invention herein provides a method for recovering a polypeptide comprising exposing a composition comprising a polypeptide to a reagent which binds to, or modifies, the polypeptide, wherein the reagent is immobilized on a solid phase; and then passing the composition through a filter bearing a charge which is opposite to the charge of the reagent in the composition, so as to remove leached reagent from the composition.
    Type: Grant
    Filed: August 27, 2001
    Date of Patent: April 6, 2004
    Assignee: Genentech, Inc.
    Inventors: Gregory S. Blank, Daljit S. Narindray, Gerardo A. Zapata
  • Protein recovery
    Publication number: 20020058324
    Abstract: The invention herein provides a method for recovering a polypeptide comprising exposing a composition comprising a polypeptide to a reagent which binds to, or modifies, the polypeptide, wherein the reagent is immobilized on a solid phase; and then passing the composition through a filter bearing a charge which is opposite to the charge of the reagent in the composition, so as to remove leached reagent from the composition.
    Type: Application
    Filed: August 27, 2001
    Publication date: May 16, 2002
    Applicant: Genentech, Inc.
    Inventors: Gregory S. Blank, Daljit S. Narindray, Gerardo A. Zapata
  • Protein purification
    Publication number: 20020032317
    Abstract: A method for purifying proteins by Protein A chromatography is described which comprises the steps of: (a) adsorbing the protein to Protein A immobilized on a solid phase comprising silica or glass; (b) removing contaminants bound to the solid phase by washing the solid phase with a hydrophobic electrolyte solvent; and (c) recovering the protein from the solid phase.
    Type: Application
    Filed: September 26, 2001
    Publication date: March 14, 2002
    Applicant: Genentech, Inc.
    Inventor: Gregory S. Blank
  • Protein purification
    Patent number: 6333398
    Abstract: A method for purifying proteins by Protein A chromatography is described which comprises the steps of: (a) adsorbing the protein to Protein A immobilized on a solid phase comprising silica or glass; (b) removing contaminants bound to the solid phase by washing the solid phase with a hydrophobic electrolyte solvent; and (c) recovering the protein from the solid phase.
    Type: Grant
    Filed: June 6, 2000
    Date of Patent: December 25, 2001
    Assignee: Genentech, Inc.
    Inventor: Gregory S. Blank
  • Protein recovery
    Patent number: 6322997
    Abstract: The invention herein provides a method for recovering a polypeptide comprising exposing a composition comprising a polypeptide to a reagent which binds to, or modifies, the polypeptide, wherein the reagent is immobilized on a solid phase; and then passing the composition through a filter bearing a charge which is opposite to the charge of the reagent in the composition, so as to remove leached reagent from the composition.
    Type: Grant
    Filed: December 14, 1999
    Date of Patent: November 27, 2001
    Assignee: Genentech, Inc.
    Inventors: Gregory S. Blank, Daljit S. Narindray, Gerardo A. Zapata
  • Protein purification by Protein A chromatography
    Patent number: 6127526
    Abstract: A method for purifying proteins by Protein A chromatography is described which comprises the steps of: (a) adsorbing the protein to Protein A immobilized on a solid phase comprising silica or glass; (b) removing contaminants bound to the solid phase by washing the solid phase with a hydrophobic electrolyte solvent; and (c) recovering the protein from the solid phase.
    Type: Grant
    Filed: November 20, 1997
    Date of Patent: October 3, 2000
    Assignee: Genentech, Inc.
    Inventor: Gregory S. Blank
  • Protein recovery
    Patent number: 6121428
    Abstract: The invention herein provides a method for recovering a polypeptide comprising exposing a composition comprising a polypeptide to a reagent which binds to, or modifies, the polypeptide, wherein the reagent is immobilized on a solid phase; and then passing the composition through a filter bearing a charge which is opposite to the charge of the reagent in the composition, so as to remove leached reagent from the composition.
    Type: Grant
    Filed: June 12, 1998
    Date of Patent: September 19, 2000
    Assignee: Genentech, Inc.
    Inventors: Gregory S. Blank, Daljit S. Narindray, Gerardo A. Zapata