Patents by Inventor Gregory S. Jensen

Gregory S. Jensen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and compositions for therapeutic use of RNA interference
    Publication number: 20090304798
    Abstract: The present invention provides methods and compositions for attenuating expression of a target gene in vivo. In general, the method includes administering RNAi constructs (such as small-interfering RNAs (i.e., siRNAs) that are targeted to particular mRNA sequences, or nucleic acid material that can produce siRNAs in a cell), in an amount sufficient to attenuate expression of a target gene by an RNA interference mechanism, e.g., in a sequence-dependent, PKR-independent manner. In particular, the subject method can be used to alter the growth, survival or differentiation of cells for therapeutic and cosmetic purposes.
    Type: Application
    Filed: January 9, 2009
    Publication date: December 10, 2009
    Applicant: Insert Therapeutics, Inc.
    Inventors: Mark E. Davis, Gregory S. Jensen, Suzie Hwang Pun
  • Methods and compositions for therapeutic use of RNA interference
    Publication number: 20040063654
    Abstract: The present invention provides methods and compositions for attenuating expression of a target gene in vivo. In general, the method includes administering RNAi constructs (such as small-interfering RNAs (i.e., siRNAs) that are targeted to particular mRNA sequences, or nucleic acid material that can produce siRNAs in a cell), in an amount sufficient to attenuate expression of a target gene by an RNA interference mechanism, e.g., in a sequence-dependent, PKR-independent manner. In particular, the subject method can be used to alter the growth, survival or differentiation of cells for therapeutic and cosmetic purposes.
    Type: Application
    Filed: May 15, 2003
    Publication date: April 1, 2004
    Inventors: Mark E. Davis, Gregory S. Jensen, Suzie Hwang Pun
  • METHODS AND COMPOSITIONS FOR THERAPEUTIC USE OF RNA INTERFERENCE
    Publication number: 20030157030
    Abstract: The present invention provides methods and compositions for attenuating expression of a target gene in vivo. In general, the method includes administering RNAi constructs (such as small-interfering RNAs (i.e., siRNAs) that are targeted to particular mRNA sequences, or nucleic acid material that can produce siRNAs in a cell), in an amount sufficient to attenuate expression of a target gene by an RNA interference mechanism, e.g., in a sequence-dependent, PKR-independent manner. In particular, the subject method can be used to alter the growth, survival or differentiation of cells for therapeutic and cosmetic purposes.
    Type: Application
    Filed: November 4, 2002
    Publication date: August 21, 2003
    Applicant: Insert Therapeutics, Inc.
    Inventors: Mark E. Davis , Gregory S. Jensen , Suzie Hwang Pun