Patents by Inventor Gregory Sempowski

Gregory Sempowski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CORONAVIRUS ANTIBODIES AND USES THEREOF
    Publication number: 20250188154
    Abstract: Recombinant monoclonal antibodies (mAbs) and fragments that bind specifically to coronavirus spike protein. Herein, monoclonal antibodies were recombinantly derived from isolated B cell from coronavirus infected individuals. Such antibodies bind various epitopes on the coronavirus spike protein and are neutralizing. The invention provides methods for using the inventive antibodies in prophylactic and/or therapeutic methods to prevent or treat coronavirus infection.
    Type: Application
    Filed: September 15, 2021
    Publication date: June 12, 2025
    Inventors: Gregory Sempowski, Barton F. Haynes, Kevin Saunders, Dapeng Li, Xiaozhi Lu, Robert J. Edwards, Priyamvada Acharya, Kartik Manne, Sophie Gobeil, John R. Mascola, Barney S. Graham, Tongqing Zhou
  • INFLUENZA NEUTRALIZING ANTIBODIES AND THEIR USES
    Publication number: 20220340644
    Abstract: The invention relates to human antibodies binding to and neutralizing Influenza (flu) virus and their uses.
    Type: Application
    Filed: September 18, 2020
    Publication date: October 27, 2022
    Inventors: David EASTERHOFF, Gregory SEMPOWSKI
  • Vaccine Adjuvant
    Publication number: 20080085261
    Abstract: The present invention relates, in general, to a method of enhancing an immune response in a mammal and, in particular, to a method of enhancing an immune response to a vaccine comprising suppressing the number and/or function of regulatory T cells. The invention further relates to compounds and compositions suitable for use in such a method.
    Type: Application
    Filed: October 19, 2005
    Publication date: April 10, 2008
    Inventors: Barton Haynes, Gregory Sempowski, James Peacock
  • Vaccine adjuvant
    Publication number: 20060165687
    Abstract: The present invention relates, in general, to a method of enhancing an immune response in a mammal and, in particular, to a method of enhancing an immune response to a vaccine comprising suppressing the number and/or function of regulatory T cells. The invention further relates to compounds and compositions suitable for use in such a method.
    Type: Application
    Filed: December 14, 2005
    Publication date: July 27, 2006
    Applicant: DUKE UNIVERSITY
    Inventors: Barton Haynes, Gregory Sempowski, James Peacock