Patents by Inventor Gregory SIN

Gregory SIN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240199604
    Abstract: The invention provides compounds, and methods of using those compounds to treat neurodegenerative diseases.
    Type: Application
    Filed: September 15, 2023
    Publication date: June 20, 2024
    Applicant: The Regents of the University of California
    Inventors: Stanley B. Prusiner, Nick A. Paras, Jay Conrad, Ny Sin, Sandeep Raikar, Mark Vander Wal, Jean-Marc M. Grandjean, Shigeo Yamanoi, Masahiro Inoue, Shimpei Hirano, Masatoshi Honzumi, Koji Sasaki, Yamato Suzuki, Atsushi Tengeiji, Daniel R. Southworth, Darren Hutt, Jacob I. Ayers, Steven H. Olson, Cuong Quoc Ly, John West, Gregory E. Merz, Helene Viart, Osamu Iwamoto
  • Publication number: 20240197682
    Abstract: A method of inhibiting propagation of protein misfolding associated with a neurological disease, is carried out by contacting an environment populated with a propagating amyloid conformation of a protein (prion) associated with a neurological disease with molecules which binds multiple adjacent sites of the protein assemblies and allowing the molecules to bind multiple cites of the protein assemblies; and thereby impeding propagation of the disease-associated conformation of the protein in the environment. Drug/prion complexes are formed and uses of the drugs in detection and treatment of neurodegenerative diseases are disclosed.
    Type: Application
    Filed: September 15, 2023
    Publication date: June 20, 2024
    Applicant: The Regents of the University of California
    Inventors: Stanley B. Prusiner, Nick A. Paras, Jay Conrad, Ny Sin, Sandeep Raikar, Mark Vander Wal, Jean-Marc M. Grandjean, Shigeo Yamanoi, Masahiro Inoue, Shimpei Hirano, Masatoshi Honzumi, Osamu Iwamoto, Koji Sasaki, Yamato Suzuki, Atsushi Tengeiji, Daniel R. Southworth, Darren Hutt, Jacob I. Ayers, Steven H. Olson, Cuong Quoc Ly, John West, Gregory E. Merz, Helene Viart
  • Publication number: 20240201205
    Abstract: A method for detecting a neurological disease the method comprising isolating brain tissue from its natural environment, contacting the brain tissue with a labeled molecule which binds to multiple sites of stacked proteins associated with neurodegenerative disease, determining the binding of the labeled molecule; and thereby determining a neurodegenerative disease associated with the brain tissue.
    Type: Application
    Filed: September 15, 2023
    Publication date: June 20, 2024
    Applicant: The Regents of the University of California
    Inventors: Stanley B. Prusiner, Nick A. Paras, Jay Conrad, Ny Sin, Sandeep Raikar, Mark Vander Wal, Jean-Marc M. Grandjean, Shigeo Yamanoi, Masahiro Inoue, Shimpei Hirano, Masatoshi Honzumi, Osamu Iwamoto, Koji Sasaki, Yamato Suzuki, Atsushi Tengeiji, Daniel R. Southworth, Darren Hutt, Jacob I. Ayers, Steven H. Olson, Cuong Quoc Ly, John West, Gregory E. Merz, Helene Viart
  • Publication number: 20220187076
    Abstract: Example implementations involve systems and methods to advance data acquisition systems for automated visual inspection using a mobile camera infrastructure. The example implementations address the uncertainty of localization and navigation under semi-controlled environments. The approach combines object detection models and navigation planning to control the quality of visual inputs in the inspection process. The solution guides the operator (human or robot) to collect only valid viewpoints to achieve higher accuracy. Finally, the learning models and navigation planning are generalized to multiple type and size of inspection objects.
    Type: Application
    Filed: December 11, 2020
    Publication date: June 16, 2022
    Inventors: Maria Teresa GONZALEZ DIAZ, Adriano S. ARANTES, Dipanjan GHOSH, Mahbubul ALAM, Gregory SIN, Chetan GUPTA