Patents by Inventor Gregory T. STOKLOSA

Gregory T. STOKLOSA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SUBSTITUTED PYRIMIDINE AS A PROSTAGLANDIN D2 RECEPTOR ANTAGONIST
    Publication number: 20130005741
    Abstract: The present invention is directed to a 2,6-substituted-4-monosubstitutedamino-pyrimidine compound of formula (I): or an enantiomer thereof, or an ester prodrug or a pharmaceutically acceptable salt thereof, or a pharmaceutical composition comprising such a compound. The invention also includes a method of treatment of a patient by the administration of a pharmaceutically effective amount of such a compound.
    Type: Application
    Filed: September 11, 2012
    Publication date: January 3, 2013
    Applicant: AVENTIS PHARMACEUTICALS INC.
    Inventors: Keith John HARRIS, Joacy C. AGUIAR, Patrick Wai-Kwok SHUM, Zhicheng ZHAO, Gregory B. POLI, Gregory T. STOKLOSA, Yong-Mi CHOI-SLEDESKI, Stephan REILING
  • [4 [4-(AMINOMETHYL-2-FLUORO-PHENYL)-PIPERIDIN-1-YL]-(1H-PYRROLO-PYRIDIN-YL)-METHANONES AND SYNTHESIS THEREOF
    Publication number: 20120245199
    Abstract: The present invention relates herein to compounds and compositions for the treatment and amelioration of inflammatory disease. Specifically the present invention relates to compounds that having a tryptase inhibition activity and the intermediates thereof, pharmaceutical compositions comprising such compounds, and a method of treating subjects suffering from a condition disease or disorder that can be ameliorated by the administration of an inhibitor of tryptase.
    Type: Application
    Filed: June 5, 2012
    Publication date: September 27, 2012
    Applicant: SANOFI
    Inventors: Yong Mi CHOI-SLEDESKI, Thaddeus R. NIEDUZAK, Gregory B. POLI, Patrick Wai-Kwok SHUM, Gregory T. STOKLOSA, Zhicheng ZHAO
  • INDOLYL-PIPERIDINYL BENZYLAMINES AS BETA-TRYPTASE INHIBITORS
    Publication number: 20120245161
    Abstract: The present invention discloses and claims a series of substituted indolyl-piperidinyl benzylamines of the formula wherein R1, R2, R4 and R5 are as described herein. More specifically, the compounds of this invention are inhibitors of ?-tryptase and are, therefore, useful as pharmaceutical agents. Additionally, this invention also discloses methods of preparation of substituted indolyl-piperidinyl benzylamines.
    Type: Application
    Filed: June 5, 2012
    Publication date: September 27, 2012
    Applicant: SANOFI
    Inventors: Yong Mi CHOI-SLEDESKI, Guyan LIANG, Thaddeus R. NIEDUZAK, Gregory B. POLI, Patrick Wai-Kwok SHUM, Gregory T. STOKLOSA, Zhicheng ZHAO