Abstract: The invention generally relates to novel polymers (SMAMPs) and their syntheses and use. The polymers exhibit promising properties of AMPs. In particularly, for example, a ring-opening metathesis polymerization (ROMP) platform was developed that allows syntheses of SMAMPs that employ a minimum number of norbornene-based building blocks and/or enable easy and independent variation of hydrophobic and hydrophilic groups in the monomer units and/or along the polymeric backbone to finetune and select desirable properties of the polymers.

Abstract: The invention generally relates to novel polymers (SMAMPs) and their syntheses and use. The polymers exhibit promising properties of AMPs. In particularly, for example, a ring-opening metathesis polymerization (ROMP) platform was developed that allows syntheses of SMAMPs that employ a minimum number of norbornene-based building blocks and/or enable easy and independent variation of hydrophobic and hydrophilic groups in the monomer units and/or along the polymeric backbone to finetune and select desirable properties of the polymers.

Abstract: An operating environment emulation system includes a separate peripheral emulation system having a memory device. The memory device is operable to store one or more executable programs, referred to as emulators. The emulators are operable to emulate an original operating environment. Multiple emulators may be deployed on the emulation system to allow execution and presentation of an original operating environment on several different host computers. The system also includes a method for connecting the emulation system to a host computer or accessory device upon which the emulation will run. The emulator may employ insulation processes to limit interaction between the emulation system and host computer resources.

Abstract: The invention generally relates to novel polymers (SMAMPs) and their syntheses and use. The polymers exhibit promising properties of AMPs. In particularly, for example, a ring-opening metathesis polymerization (ROMP) platform was developed that allows syntheses of SMAMPs that employ a minimum number of norbornene-based building blocks and/or enable easy and independent variation of hydrophobic and hydrophilic groups in the monomer units and/or along the polymeric backbone to finetune and select desirable properties of the polymers.

Abstract: The present invention discloses compositions of facially amphiphilic polymers and oligomers and their use in methods for treating or reducing cancers in humans or animals.

Abstract: Polynorbornene derivatives exhibiting antibacterial activity and low hemolytic activity are described herein. Antimicrobial compositions and pharmaceutical compositions comprising polynorbonene derivatives and methods of using the same are also described. Such compositions, which exhibit substantial antibacterial activity and low hemolytic activity, may be suitable for material applications and therapeutic uses.

Abstract: The present invention discloses methods of use of facially amphiphilic polymers and oligomers, including pharmaceutical uses of the polymers and oligomers as antimicrobial agents and antidotes for hemorrhagic complications associated with heparin therapy. The present invention also discloses novel facially amphiphilic polymers and oligomers and their compositions, including pharmaceutical compositions. The present invention further discloses the design and synthesis of facially amphiphilic polymers and oligomers.

Abstract: A-B-A triblock copolymers tailored to produce certain embodiments that have specific properties, such as relatively high elastic modulus. Also provided are methods of designing and synthesizing such a triblock copolymer having desired properties, such non-limiting copolymers comprising a poly(ethylene oxide) block and a block selected from at least one of poly(L-lactic acid) and poly(D,L-lactic acid).

Abstract: The present invention discloses methods of use of facially amphiphilic polyaryl and polyarylalkynyl polymers and oligomers, including, but not limited to, pharmaceutical uses of the polymers and oligomers as antimicrobial agents and as antidotes for hemorrhagic complications associated with heparin therapy. The present invention also discloses novel facially amphiphilic polyaryl and polyarylalkynyl polymers and oligomers, compositions of the novel polymers and oligomers, including pharmaceutical compositions, and methods of designing and synthesizing the facially amphiphilic polyaryl and polyarylalkynyl polymers and oligomers.