Patents by Inventor Gregory Tochtrop

Gregory Tochtrop has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Visual cycle modulators
    Patent number: 12144788
    Abstract: A method of treating an ocular disorder in a subject in need thereof includes administering to the subject a therapeutically effective amount of a retinal sequestering compound of formula (I).
    Type: Grant
    Filed: February 22, 2022
    Date of Patent: November 19, 2024
    Assignees: CASE WESTERN RESERVE UNIVERSITY, THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERAN AFFAIRS
    Inventors: Krzysztof Palczewski, Philip Kiser, Jianye Zhang, Mohsen Badiee, Gregory Tochtrop
  • COMPOSITIONS AND METHODS FOR THE TREATMENT OF OCULAR DISORDERS
    Publication number: 20240122876
    Abstract: A method of treating an ocular disorder in a subject in need thereof includes administering to the subject a therapeutically effective amount of a compound of formula (I) or a pharmaceutically acceptable salt, tautomer, or solvate thereof.
    Type: Application
    Filed: February 1, 2022
    Publication date: April 18, 2024
    Inventors: Gregory Tochtrop, Philip Kiser, Jianye Zhang, Krzysztof Palczewski
  • VISUAL CYCLE MODULATORS
    Publication number: 20220175700
    Abstract: A method of treating an ocular disorder in a subject in need thereof includes administering to the subject a therapeutically effective amount of a retinal sequestering compound of formula (I).
    Type: Application
    Filed: February 22, 2022
    Publication date: June 9, 2022
    Inventors: Krzysztof Palczewski, Philip Kiser, Jianye Zhang, Mohsen Badiee, Gregory Tochtrop
  • Visual cycle modulators
    Patent number: 11253489
    Abstract: A method of treating an ocular disorder in a subject in need thereof includes administering to the subject a therapeutically effective amount of a retinal sequestering compound of formula (I).
    Type: Grant
    Filed: February 27, 2018
    Date of Patent: February 22, 2022
    Assignees: CASE WESTERN RESERVE UNIVERSITY, THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERAN AFFAIRS
    Inventors: Krzysztof Palczewski, Philip Kiser, Jianye Zhang, Mohsen Badiee, Gregory Tochtrop
  • COMPOSITIONS AND METHODS FOR INHIBITING BETA AMYLOID SECRETION
    Publication number: 20130158112
    Abstract: A pharmaceutical composition for inhibiting amyloid beta peptide in a subject includes a compound having the formula (I): where M is selected from a substituted or unsubstituted alkyl, halo, alkoxy, aryl, cyclic, or heterocyclic group; p is an integer from 0-3; X1 is a 3-9 atoms in length linker connecting A and B; B is selected from a substituted or unsubstituted aryl, alkoxy or amine group; and a pharmaceutically acceptable salt thereof; and a pharmaceutical carrier.
    Type: Application
    Filed: June 20, 2012
    Publication date: June 20, 2013
    Inventors: Jonathan D. Smith, Enakshi Chakrabarti, Subrata Ghosh, Marti Sayre, Gregory Tochtrop