Abstract: A device for intraosseous injection is provided which can accurately, quickly, and safely introduce desired fluid into a patient's bone marrow. The intraosseous injector includes a housing, a container located within the housing, a hollow needle, and a valve. The intraosseous injector may further include a release mechanism comprising a bone probe needle and a movable release member. The intraosseous injector may include a depth limiter mechanism operable to limit a depth of penetration of the needle relative to a surface of a bone. A method for intraosseous injection is also provided.

Abstract: An imaging device having an imaging field of view, the imaging device including at least one illumination port configured to output light for illuminating a target; an imaging sensor to detect light traveling along an optical path to the imaging sensor; and a first movable window positioned upstream of the sensor with respect to a direction of travel of light along the optical path, wherein the first movable window is configured to move into the optical path in a deployed position for modifying light received from the target.

Abstract: Systems and methods for storing data for a first time series of fluorescence images of the subject acquired during a first imaging session, storing data for a second time series of fluorescence images of the subject acquired during a second imaging session, receiving a request to view attributes of the subject, and in response to receiving the request, displaying a user interface on the display, the user interface comprising a first image showing a visually enhanced attribute of the subject, wherein the first image is generated from the data for the first time series of fluorescence images, and a second image showing the visually enhanced attribute of the subject, wherein the second image is generated from the data for the second time series of fluorescence images.

Abstract: The present invention relates to light applicators, systems comprising light applicators, and methods for their use. One aspect of the invention provides a light applicator configured for contacting a portion of a subject's body surface and controllably applying light irradiation thereto. The light applicator comprises a housing, the housing comprising a treatment plate for contacting the portion of the subject's body surface and having one or more windows. One or more light emitters are disposed inside the light applicator and projecting toward the corresponding one or more windows of the treatment plate. A heat spreader plate is disposed inside the light applicator. One or more heat conducting members thermally connect the treatment plate to the heat spreader plate.

Abstract: Apparatus is described for measuring and displaying the magnitude of traction forces applied to a patient's lower limbs during surgery, and for measuring the direction and magnitude of counter-traction forces applied to the patient's body by the perineal post located at the patient's groin to oppose traction forces applied to the patient's lower limbs.

Abstract: According to one aspect, the invention relates to an angular optical filtering element (Ei) optimized for angular filtering about a given operating angle of incidence (?i, 1) in a given spectral band. The angular filtering element (Ei) comprises a first nanostructured, band-pass, spectral filter (11i, 301) and a second nanostructured, band-pass, spectral filter (12i, 302). Each of the first and second spectral filters comprises, respectively, in said spectral band, a first and a second central filtering wavelength that respectively has a first and second angular dispersion curve defined depending on the angle of incidence (?inc) on the optical filtering element (Ei), the curves of angular dispersion being secant about the operating angle of incidence (?i, 1) of the optical filtering element. The invention applies to the production of a selective angular filtering device and to a multidirectional optical detection system.

Abstract: An apparatus and method for introducing portals into bone is described herein. An example apparatus for introducing portals into bone includes a handle, a base, and a driving member. The driving member can be made to project past the base by operating the handle. The base is detachable from the handle. The apparatus also includes a guide coupled at a first end to the handle and at a second end to the base. The base is detachably coupled to the guide. A base coupling detachably coupling the base to the guide includes an actuating member movable between a coupled configuration wherein the base is coupled to the guide and an uncoupled configuration wherein the base is released from the guide. The actuating member is arranged so that motion of the handle toward the base moves the actuating member from the coupled configuration to the uncoupled configuration.

Abstract: Described herein are introducer devices and methods for using an introducer device to facilitate passing an endoluminal instrument to a target region of a body cavity. An introducer device may include a tubular member having an inner wall that defines a channel configured to receive the endoluminal instrument and a plurality of projections disposed in the channel at perimetrically spaced apart locations around the inner wall, where the projections extend inward and are configured to offset the endoluminal instrument from the inner wall, thereby creating a space between the endoluminal instrument and the inner wall. A method for using an introducer device may include passing the endoluminal instrument to a first instrument insertion depth within the introducer device, advancing the introducer device in the body cavity, and advancing the endoluminal instrument to a second instrument insertion depth within the introducer device.

Abstract: An apparatus and method for introducing portals into bone is described herein. An example apparatus for introducing portals into bone includes a handle, a base, and a driving member. The driving member can be made to project past the base by operating the handle. The base is detachable from the handle. The apparatus also includes a guide coupled at a first end to the handle and at a second end to the base. The base is detachably coupled to the guide. A base coupling detachably coupling the base to the guide includes an actuating member movable between a coupled configuration wherein the base is coupled to the guide and an uncoupled configuration wherein the base is released from the guide. The actuating member is arranged so that motion of the handle toward the base moves the actuating member from the coupled configuration to the uncoupled configuration.

Abstract: Apparatus is described for measuring and displaying the magnitude of traction forces applied to a patient's lower limbs during surgery, and for measuring the direction and magnitude of counter-traction forces applied to the patient's body by the perineal post located at the patient's groin to oppose traction forces applied to the patient's lower limbs.

Abstract: An imaging device may include a first illumination port to output first light having a first illumination distribution at a target to illuminate the target, a second illumination port to output second light having a second illumination distribution at the target to illuminate the target, the second illumination distribution being substantially similar to the first illumination distribution at the target, the second illumination port being spaced apart from the first illumination port, the first and second illumination distributions being simultaneously provided to the target and overlapping at the target. The illumination from the first and second ports may be matched to a same aspect ratio and field of view coverage as the imaging field of view.

Abstract: Methods and systems for alignment of a subject for medical imaging are disclosed, and involve providing a reference image of an anatomical region of the subject, the anatomical region comprising a target tissue, processing the reference image to generate an alignment reference image, displaying the alignment reference image concurrently with real-time video of the anatomical region, and aligning the real-time video with the alignment reference image to overlay the real-time video with the alignment reference image. Following such alignment, the subject may be imaged using, for example, fluorescence imaging, wherein the fluorescence imaging may be performed by an image acquisition assembly aligned in accordance with the alignment.

Abstract: Apparatus is described for measuring and displaying the magnitude of traction forces applied to a patient's lower limbs during surgery, and for measuring the direction and magnitude of counter-traction forces applied to the patient's body by the perineal post located at the patient's groin to oppose traction forces applied to the patient's lower limbs.

Abstract: Systems and methods for storing data for a first time series of fluorescence images of the subject acquired during a first imaging session, storing data for a second time series of fluorescence images of the subject acquired during a second imaging session, receiving a request to view attributes of the subject, and in response to receiving the request, displaying a user interface on the display, the user interface comprising a first image showing a visually enhanced attribute of the subject, wherein the first image is generated from the data for the first time series of fluorescence images, and a second image showing the visually enhanced attribute of the subject, wherein the second image is generated from the data for the second time series of fluorescence images.

Abstract: An apparatus and method for introducing portals into bone is described herein. An example apparatus for introducing portals into bone includes a handle, a base, and a driving member. The driving member can be made to project past the base by operating the handle. The base is detachable from the handle. The apparatus also includes a guide coupled at a first end to the handle and at a second end to the base. The base is detachably coupled to the guide. A base coupling detachably coupling the base to the guide includes an actuating member movable between a coupled configuration wherein the base is coupled to the guide and an uncoupled configuration wherein the base is released from the guide. The actuating member is arranged so that motion of the handle toward the base moves the actuating member from the coupled configuration to the uncoupled configuration.

Abstract: An apparatus and method for introducing portals into bone is described herein. An example apparatus for introducing portals into bone includes a handle, a base, and a driving member. The driving member can be made to project past the base by operating the handle. The base is detachable from the handle. The apparatus also includes a guide coupled at a first end to the handle and at a second end to the base. The base is detachably coupled to the guide. A base coupling detachably coupling the base to the guide includes an actuating member movable between a coupled configuration wherein the base is coupled to the guide and an uncoupled configuration wherein the base is released from the guide. The actuating member is arranged so that motion of the handle toward the base moves the actuating member from the coupled configuration to the uncoupled configuration.

Abstract: Adaptive user interfaces and techniques therefor are provided. In accordance with one example, a method includes, at an electronic device having a display: displaying, on the display, a first user interface comprising a first affordance associated with a first function; receiving a first user input corresponding to a request to display a second affordance associated with a second function; in response to the first user input, displaying the second affordance; receiving a second user input corresponding to a selection of the second affordance; in response to the second user input: performing the second function; and displaying a second user interface comprising the first affordance and the second affordance.

Abstract: According to one aspect, the invention relates to an angular optical filtering element (?i) optimised for angular filtering about a given operating angle of incidence (?i, 1) in a given spectral band. The angular filtering element (?i) comprises a first nanostructured, band-pass, spectral filter (11i, 301) and a second nanostructured, band-pass, spectral filter (12i, 302). Each of the first and second spectral filters comprises, respectively, in said spectral band, a first and a second central filtering wavelength that respectively has a first and second angular dispersion curve defined depending on the angle of incidence (?inc) on the optical filtering element (?i), the curves of angular dispersion being secant about the operating angle of incidence (?i, 1) of the optical filtering element. The invention applies to the production of a selective angular filtering device and to a multidirectional optical detection system.

Abstract: Apparatus is described for measuring and displaying the magnitude of traction forces applied to a patient's lower limbs during surgery, and for measuring the direction and magnitude of counter-traction forces applied to the patient's body by the perineal post located at the patient's groin to oppose traction forces applied to the patient's lower limbs.

Abstract: According to one aspect, the invention relates a spectral band-pass filter, which is optimized for the transmission of an incident wave at at least a first given central wavelength ?0, and which includes: a metal grating having a thickness (t) greater than approximately ?0/50 and including at least a first set of substantially identical, parallel slots having a width (W) less than around ?0/10, and being spaced apart periodically or quasi-periodically according to a first period that is less than said first central wavelength, a layer of dielectric material having a thickness (h) and a given refractive index (ng), which is coupled to the metal grating to form a waveguide for the waves diffracted by the grating, said first period of the grating being designed such that only orders 0 and ±1 of a wave having normal incidence and a wavelength ?0 are diffracted in the layer of dielectric material, the assembly of the dielectric layer and grating being suspended, during use, in a fluid having a refractive index of