Abstract: An oxygen management device adapted to mount on a post on a compressed oxygen cylinder. The device includes a manifold block which is attached to the oxygen cylinder post. A pressure regulator is mounted directly on and is integral with the manifold block for reducing the oxygen pressure to a desired level. The manifold block also mounts an overpressure relief valve, a solenoid operated flow control valve, a bypass valve, a continuous flow restrictor and a pressure gauge. The manifold and the components mounted thereon, a control circuit and a battery for operating the control circuit are mounted in an annular housing which has a central opening for receiving the oxygen cylinder post. The control circuit senses when a patient inhales in a nasal cannula and opens the flow control valve to deliver a predetermined dose of oxygen to the nasal cannula at the beginning of inhalation.