Patents by Inventor Gregory William Auner
Gregory William Auner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240133739Abstract: Apparatuses, systems, and methods for Raman spectroscopy are described. In certain implementations, a spectrometer is provided. The spectrometer may include a plurality of optical elements, comprising an entrance aperture, a collimating element, a volume phase holographic grating, a focusing element, and a detector array. The plurality of optical elements are configured to transfer the light beam from the entrance aperture to the detector array with a high transfer efficiency over a preselected spectral band.Type: ApplicationFiled: May 17, 2023Publication date: April 25, 2024Applicant: Wayne State UniversityInventors: Gregory William Auner, Michelle Ann Brusatori, Changhe Huang
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Publication number: 20240060899Abstract: Apparatuses, systems, and methods for analyzing a sample are provided. In some embodiments, a system includes a test assembly that comprises: a sample analyzer configured to provide data related to the sample; and a processing unit configured to analyze the data provided by the sample analyzer. The system is configured to identify at least one target in the sample.Type: ApplicationFiled: January 5, 2022Publication date: February 22, 2024Inventors: Ehsan MAJIDI, Changhe HUANG, Gregory William AUNER
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Patent number: 11698304Abstract: Apparatuses, systems, and methods for Raman spectroscopy are described. In certain implementations, a spectrometer is provided. The spectrometer may include a plurality of optical elements, comprising an entrance aperture, a collimating element, a volume phase holographic grating, a focusing element, and a detector array. The plurality of optical elements are configured to transfer the light beam from the entrance aperture to the detector array with a high transfer efficiency over a preselected spectral band.Type: GrantFiled: June 25, 2019Date of Patent: July 11, 2023Assignee: Wayne State UniversityInventors: Gregory William Auner, Michelle Ann Brusatori, Changhe Huang
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Patent number: 11375897Abstract: A system for characterization of a brain tissue sample includes a laser having an excitation fiber and a probe coupled to the excitation fiber for irradiating the brain tissue sample with light at an excitation wavelength. The probe further includes a plurality of return fibers for receiving light scattered from the brain tissue sample, wherein each return fiber includes a microfilter that permits light to pass for a different, spaced apart marker region. A Raman spectrometer is in communication with the plurality of return fibers, and a processor is in communication with the Raman spectrometer for analyzing Raman spectra within the marker regions to identify a tissue type of the brain tissue sample as one of normal white matter brain tissue, normal grey matter brain tissue, brain tumor tissue, infiltrating tumor tissue, and necrotic tissue.Type: GrantFiled: April 20, 2018Date of Patent: July 5, 2022Assignees: Henry Ford Health System, Wayne State UniversityInventors: Gregory William Auner, Michelle Brusatori, Steven N. Kalkanis, Lisa Scarpace
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Patent number: 11236379Abstract: A Raman spectroscopy based system and method for examination and interrogation provides a method for rapid and cost effective screening of various protein-based compounds such as bacteria, virus, drugs, and tissue abnormalities. A hand-held spectroscope includes a laser and optical train for generating a Raman-shifting sample signal, signal processing and identification algorithms for signal conditioning and target detection with combinations of ultra-high resolution micro-filters and an imaging detector array to provide specific analysis of target spectral peaks within discrete spectral bands associated with a target pathogen.Type: GrantFiled: February 25, 2019Date of Patent: February 1, 2022Assignees: Seraph Biosciences, Inc., Wayne State UniversityInventors: Gregory William Auner, Charles Shanley, Michelle Brusatori, Tara Twomey, David Sant
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Publication number: 20200264050Abstract: Apparatuses, systems, and methods for Raman spectroscopy are described. In certain implementations, a spectrometer is provided. The spectrometer may include a plurality of optical elements, comprising an entrance aperture, a collimating element, a volume phase holographic grating, a focusing element, and a detector array. The plurality of optical elements are configured to transfer the light beam from the entrance aperture to the detector array with a high transfer efficiency over a preselected spectral band.Type: ApplicationFiled: June 25, 2019Publication date: August 20, 2020Applicant: Wayne State UniversityInventors: Gregory William Auner, Michelle Ann Brusatori, Changhe Huang
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Publication number: 20200138293Abstract: A system for characterization of a brain tissue sample includes a laser having an excitation fiber and a probe coupled to the excitation fiber for irradiating the brain tissue sample with light at an excitation wavelength. The probe further includes a plurality of return fibers for receiving light scattered from the brain tissue sample, wherein each return fiber includes a microfilter that permits light to pass for a different, spaced apart marker region. A Raman spectrometer is in communication with the plurality of return fibers, and a processor is in communication with the Raman spectrometer for analyzing Raman spectra within the marker regions to identify a tissue type of the brain tissue sample as one of normal white matter brain tissue, normal grey matter brain tissue, brain tumor tissue, infiltrating tumor tissue, and necrotic tissue.Type: ApplicationFiled: April 20, 2018Publication date: May 7, 2020Applicants: HENRY FORD HEALTH SYSTEM, WAYNE STATE UNIVERSITYInventors: Gregory William AUNER, Michelle BRUSATORI, Steven N. KALKANIS, Lisa SCARPACE
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Publication number: 20190203255Abstract: A Raman spectroscopy based system and method for examination and interrogation provides a method for rapid and cost effective screening of various protein-based compounds such as bacteria, virus, drugs, and tissue abnormalities. A hand-held spectroscope includes a laser and optical train for generating a Raman-shifting sample signal, signal processing and identification algorithms for signal conditioning and target detection with combinations of ultra-high resolution micro-filters and an imaging detector array to provide specific analysis of target spectral peaks within discrete spectral bands associated with a target pathogen.Type: ApplicationFiled: February 25, 2019Publication date: July 4, 2019Applicants: Seraph Biosciences, Inc., Wayne State UniversityInventors: Gregory William Auner, Charles Shanley, Michelle Brusatori, Tara Twomey, David Sant
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Patent number: 10253346Abstract: A Raman spectroscopy based system and method for examination and interrogation provides a method for rapid and cost effective screening of various protein-based compounds such as bacteria, virus, drugs, and tissue abnormalities. A hand-held spectroscope includes a laser and optical train for generating a Raman-shifting sample signal, signal processing and identification algorithms for signal conditioning and target detection with combinations of ultra-high resolution micro-filters and an imaging detector array to provide specific analysis of target spectral peaks within discrete spectral bands associated with a target pathogen.Type: GrantFiled: August 7, 2014Date of Patent: April 9, 2019Assignees: Seraph Biosciences, Inc., Wayne State UniversityInventors: Gregory William Auner, Charles Shanley, Michelle Brusatori, Tara Twomey, David Sant
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Publication number: 20160177366Abstract: A Raman spectroscopy based system and method for examination and interrogation provides a method for rapid and cost effective screening of various protein-based compounds such as bacteria, virus, drugs, and tissue abnormalities. A hand-held spectroscope includes a laser and optical train for generating a Raman-shifting sample signal, signal processing and identification algorithms for signal conditioning and target detection with combinations of ultra-high resolution micro-filters and an imaging detector array to provide specific analysis of target spectral peaks within discrete spectral bands associated with a target pathogen.Type: ApplicationFiled: August 7, 2014Publication date: June 23, 2016Applicants: SERAPH BIOSCIENCES, LLC, WAYNE STATE UNIVERSITYInventors: Gregory William Auner, Charles Shanley, Michelle Brusatori, Tara Twomey, David Sant
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Publication number: 20160139051Abstract: A portable apparatus and method for distinguishing between different tissue types, such as normal tissue, necrotic tissue, and tumor tissue are provided, where the apparatus includes a housing and a plurality of Raman spectrometers disposed within the housing, each spectrometer having a different spectral region. A processor is provided in communication with the plurality of spectrometers, the processor analyzing output from the plurality of spectrometers to identify the tissue type of the tissue sample. A method of selecting the spectral regions which provide a desired combined classification accuracy for determining the tissue type is also provided.Type: ApplicationFiled: July 11, 2014Publication date: May 19, 2016Inventors: Gregory William AUNER, Rachel KAST, Steven KALKANIS, Mark ROSENBLUM
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Patent number: 7022991Abstract: A pyroelectric sensor having an active regulation for maximizing pyroelectric sensor sensitivity is disclosed. The pyroelectric sensor comprises a ferroelectric transducer, and a regulator. The ferroelectric transducer may either be a homogenous ferroelectric transducer, a compositionally graded ferroelectric transducer, or an externally graded ferroelectric transducer. The regulator may either be an excitation regulator or a temperature regulator. A method for regulating the excitation or the temperature of a pyroelectric sensor for maximizing sensitivity of the pyroelectric sensor is also disclosed.Type: GrantFiled: June 12, 2002Date of Patent: April 4, 2006Assignee: Delphi Technologies, Inc.Inventors: Norman William Schubring, Joseph Vito Mantese, Adolph Louis Micheli, Gregory William Auner, Ratna Naik
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Publication number: 20020190209Abstract: A pyroelectric sensor having an active regulation for maximizing pyroelectric sensor sensitivity is disclosed. The pyroelectric sensor comprises a ferroelectric transducer, and a regulator. The ferroelectric transducer may either be a homogenous ferroelectric transducer, a compositionally graded ferroelectric transducer, or an externally graded ferroelectric transducer. The regulator may either be an excitation regulator or a temperature regulator. A method for regulating the excitation or the temperature of a pyroelectric sensor for maximizing sensitivity of the pyroelectric sensor is also disclosed.Type: ApplicationFiled: June 12, 2002Publication date: December 19, 2002Inventors: Norman William Schubring, Joseph Vito Mantese, Adolph Louis Micheli, Gregory William Auner, Ratna Naik