Abstract: A high-speed digital camera system and method for processing high-speed image data is claimed. The method comprises generating images with at least 3×105 pixels at greater than 60 frames-per-second with an image sensor, downloading an image; defining an area of interest in the downloaded image comprising a plurality of adjacent pixels in which an event of interest is expected to occur, defining at least one threshold level for all pixels in the plurality; uploading the defined threshold level to a processor, retrieving pixel data in real time from the image sensor, and comparing the pixel data to the defined threshold levels. A trigger is set when the threshold levels are exceeded and the camera records the event of interest and stores it in camera memory for outputting to a remote computer.