Abstract: Electrical power is supplied to an electric vehicle rapid DC charging station requiring a multi-phase electrical input, by converting single phase utility power using high-capacity converters of various designs. In certain embodiments, a low-capacity converter may also be coupled to single-phase utility power input for provision of power to the charging station when no vehicle is present for charging. In these embodiments, a transfer switch selectively couples the high-capacity converter or low-capacity converter to the rapid charging station as needed to charge an electric vehicle. Other embodiments may also include energy storage devices for enhancing charge rates or providing charging during periods of inadequate power availability or poor utility power quality.

Abstract: Methods and apparatus for inferring protein binding based on rotational diffusion of a collection of fluorophores.

Abstract: Systems and methods for oblique plane microscopy are disclosed.

Abstract: Methods and apparatus for inferring protein binding based on rotational diffusion of a collection of fluorophores.

Abstract: Fluorescence imaging based on stimulated emission. In one example a system includes an excitation source (110) that excites fluorescent markers (122) in a sample (120) with an excitation beam (112), a stimulation source (130) that stimulates the excited fluorescent markers (122) to produce stimulated emission (124), and an objective lens (150) that receives the stimulation beam (132) and the stimulated emission (124). The system further includes a phase shifting and attenuation apparatus (200) configured to receive the stimulation beam (132) and the stimulated emission (124) from the objective lens (150), to attenuate the stimulation beam (132), and to induce a relative phase shift between a reference beam (optionally being at least a portion of the stimulation beam) and the stimulated emission, thereby causing constructive interference between the reference beam and the stimulated emission.

Abstract: Fluorescence imaging based on stimulated emission. In one example a system includes an excitation source (110) that excites fluorescent markers (122) in a sample (120) with an excitation beam (112), a stimulation source (130) that stimulates the excited fluorescent markers (122) to produce stimulated emission (124), and an objective lens (150) that receives the stimulation beam (132) and the stimulated emission (124). The system further includes a phase shifting and attenuation apparatus (200) configured to receive the stimulation beam (132) and the stimulated emission (124) from the objective lens (150), to attenuate the stimulation beam (132), and to induce a relative phase shift between a reference beam (optionally being at least a portion of the stimulation beam) and the stimulated emission, thereby causing constructive interference between the reference beam and the stimulated emission.

Abstract: The present invention provides four crystalline forms of verubecestat, as well as pharmaceutically acceptable compositions thereof, each of which may be useful in treating, preventing, ameliorating, and/or delaying the onset of an A? pathology and/or a symptom or symptoms thereof. Non-limiting examples of such A? pathologies, including Alzheimer's disease, are disclosed herein.

Abstract: The present invention provides four crystalline forms of verubecestat, as well as pharmaceutically acceptable compositions thereof, each of which may be useful in treating, preventing, ameliorating, and/or delaying the onset of an A? pathology and/or a symptom or symptoms thereof. Non-limiting examples of such A? pathologies, including Alzheimer's disease, are disclosed herein.

Abstract: A stuck lock-pin release system for a lock-pin in a cam phaser includes a stuck lock-pin detection module and a stuck lock-pin module that communicates with the stuck lock-pin detection module. The stuck-lock pin detection module periodically determines whether a lock-pin in a cam phaser is in a stuck park condition. When the lock-pin is in the stuck park condition, the stuck lock-pin module alternately biases the cam phaser in a first and second direction until the lock-pin is no longer in the stuck park condition.