Patents by Inventor Greta Van Den Berghe

Greta Van Den Berghe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and Preparations For Curing Clinically Ill Patients
    Publication number: 20100105603
    Abstract: This invention relates to a life saving medicament for critically ill patients and a method of treatment. The composition is a pharmaceutically effective amount of a blood glucose regulator which is used to control the blood glucose level.
    Type: Application
    Filed: January 6, 2010
    Publication date: April 29, 2010
    Applicant: Novo Nordisk A/S
    Inventor: Greta Van Den Berghe
  • METHODS AND PREPARATIONS FOR CURING CRITICALLY ILL PATIENTS
    Publication number: 20090181882
    Abstract: The present invention pertains to the use of a blood mannan-binding lectin (MBL) regulator for the manufacture of a life saving drug to treat or cure a critically ill patient. It further involves the use of measurements of MBL to predict mortality in critically ill ICU patients. One further aspect of present invention is to the use of monomers and oligomers of MBL in prophylactic and/or curative treatment of patients admitted to intensive care units (ICUs).
    Type: Application
    Filed: December 30, 2008
    Publication date: July 16, 2009
    Applicants: K.U. Leuven Research and Development, Aarhus Universitet, Aarhus University Hospital
    Inventors: Greta Van Den Berghe, Steffen Thiel, Troels Krarup Hansen
  • Methods and Preparations For Curing Clinically Ill Patients
    Publication number: 20090054302
    Abstract: This invention relates to a life saving medicament for critically ill patients and a method of treatment. The composition is a pharmaceutically effective amount of a blood glucose regulator which is used to control the blood glucose level.
    Type: Application
    Filed: August 22, 2008
    Publication date: February 26, 2009
    Applicant: Novo Nordisk A/S
    Inventor: Greta Van Den Berghe
  • Automatic infusion system based on an adaptive patient model
    Patent number: 7491187
    Abstract: Present invention is a system of blood glucose monitoring and intensive insulin therapy in a ICU for strict maintenance of normoglycemia which reduces intensive care and hospital mortality and morbidity of critically ill adult patients. The findings of present study also reveal factors determining insulin doses needed to maintain normoglycemia as well as the impact of insulin dose versus blood glucose level on the observed outcome benefits have been established. The invention provides a control system that adapts the flow of the insulin infusion based on insulin requirement calculated by blood glucose levels and clinical parameters such as history of diabetes, Body Mass Index, blood glucose level on admission, reason of ICU admission, time in the ICU, type and severity of illness, caloric intake, obesity, drugs affecting insulin sensitivity). This automated insulin monitoring systems significantly reduces the workload and human resource management problems for intensive insulin therapy in patients in the ICU.
    Type: Grant
    Filed: March 24, 2003
    Date of Patent: February 17, 2009
    Assignee: K.U. Leuven Research & Development
    Inventors: Greta Van Den Berghe, Daniel Berckmans, Jean-Marie Aerts, Bart De Moor, Bert Pluymers, Frank De Smet
  • Methods and preparations for curing clinically ill patients
    Patent number: 7446091
    Abstract: This invention relates to a life saving medicament for critically ill patients and a method of treatment. The composition is a pharmaceutically effective amount of a blood glucose regulator which is used to control the blood glucose level.
    Type: Grant
    Filed: May 11, 2001
    Date of Patent: November 4, 2008
    Assignee: Novo Nordisk A/S
    Inventor: Greta Van Den Berghe
  • Automatic infusion system based on an adaptive patient model
    Publication number: 20050171503
    Abstract: Present invention is a system of blood glucose monitoring and intensive insulin therapy in a ICU for strict maintenance of normoglycemia which reduces intensive care and hospital mortality and morbidity of critically ill adult patients. The findings of present study also reveal factors determining insulin doses needed to maintain normoglycemia as well as the impact of insulin dose versus blood glucose level on the observed outcome benefits have been established. The invention provides a control system that adapts the flow of the insulin infusion based on insulin requirement calculated by blood glucose levels and clinical parameters such as history of diabetes, Body Mass Index, blood glucose level on admission, reason of ICU admission, time in the ICU, type and severity of illness, caloric intake, obesity, drugs affecting insulin sensitivity). This automated insulin monitoring systems significantly reduces the workload and human resource management problems for intensive insulin therapy in patients in the ICU.
    Type: Application
    Filed: March 24, 2003
    Publication date: August 4, 2005
    Inventors: Greta Van Den Berghe, Daniel Berckmans, Jean-Marie Aerts, Bart De Moor, Bert Pluymers, Frank De Smet
  • Methods and preparations for curing clinically ill patients
    Publication number: 20020107178
    Abstract: This invention relates to a life saving medicament for critically ill patients and a method of treatment. The composition is a pharmaceutically effective amount of a blood glucose regulator which is used to control the blood glucose level.
    Type: Application
    Filed: May 11, 2001
    Publication date: August 8, 2002
    Inventor: Greta Van Den Berghe