Abstract: A photo-medicine device may include a housing having: a mounting member and an application member including an aperture. An LED array having at least one LED configured to emit light through the aperture at a first wavelength and at least one LED configured to emit light through the aperture at a second wavelength may be mounted to the mounting member. The LED array may be in thermal communication with the mounting member such that the housing functions as a heat sink for the LED array. In some embodiments, the first wavelength comprises approximately 415 nm and the second wavelength comprises approximately 660 nm. In some embodiments, the housing has a heat dissipation surface area of at least three square inches per LED watt.