Patents by Inventor Gretchen M. Argast

Gretchen M. Argast has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of EMT gene signatures in cancer drug discovery, diagnostics, and treatment
    Patent number: 9896730
    Abstract: The present invention provides diagnostic methods for assessing the EMT status of tumor cells, and for predicting the effectiveness of treatment of a cancer patient with an EGFR or IGF-1R kinase inhibitor, utilizing an EMT gene signature index score. The present invention further provides methods for treating patients with cancer that incorporate these methods.
    Type: Grant
    Filed: April 25, 2012
    Date of Patent: February 20, 2018
    Assignees: OSI Pharmaceuticals, LLC, AVEO PHARMACEUTICALS, INC.
    Inventors: Julie Kan, Stuart Thomson, Gretchen M. Argast, Matthew E. O'Connor, Murray Robinson, Bin Feng, Joerg Heyer, Maria I. Chiu, Richard Nicoletti
  • USE OF EMT GENE SIGNATURES IN CANCER DRUG DISCOVERY, DIAGNOSTICS, AND TREATMENT
    Publication number: 20120302572
    Abstract: The present invention provides diagnostic methods for assessing the EMT status of tumor cells, and for predicting the effectiveness of treatment of a cancer patient with an EGFR or IGF-1R kinase inhibitor, utilizing an EMT gene signature index score. The present invention further provides methods for treating patients with cancer that incorporate these methods.
    Type: Application
    Filed: April 25, 2012
    Publication date: November 29, 2012
    Applicants: AVEO PHARMACEUTICALS, INC., OSI Pharmaceuticals, LLC
    Inventors: Julie Kan, Stuart Thomson, Gretchen M. Argast, Matthew E. O'Connor, Murray Robinson, Bin Feng, Joerg Heyer, Maria I. Chiu, Richard Nicoletti