Patents by Inventor Grethe Nørskov Rasmussen

Grethe Nørskov Rasmussen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Dry growth hormone composition transiently linked to a polymer carrier
    Patent number: 12226457
    Abstract: The present invention relates to dry compositions of rhGH polymer prodrug containing a lyoprotectant and, optionally, one or more than one excipient. Such compositions are stable for at least 1 year, when stored at 2-8° C. The invention further relates to methods of manufacturing said compositions, containers comprising such composition as well as a kit of parts.
    Type: Grant
    Filed: May 5, 2020
    Date of Patent: February 18, 2025
    Assignee: Ascendis Pharma Endocrinology Division A/S
    Inventors: Grethe Nørskov Rasmussen, Susanne Kindermann, Harald Rau, Thomas Wegge
  • Novel Polymeric hGH Prodrugs
    Publication number: 20250032587
    Abstract: The present invention relates to a polymeric human growth hormone prodrug and dry, liquid and reconstituted pharmaceutical formulations comprising said prodrug. It furthermore relates to their use as medicaments for the treatment of diseases which can be treated with growth hormone and to methods of treatment. It also relates to methods of application of such polymeric human growth hormone prodrug or pharmaceutical formulation.
    Type: Application
    Filed: September 20, 2024
    Publication date: January 30, 2025
    Applicant: ASCENDIS PHARMA ENDOCRINOLOGY DIVISION A/S
    Inventors: Thomas Kurpiers, Harald Rau, Evelyn Exner, Steen Jensen, Grethe Nørskov Rasmussen, Torben Lessmann, Thomas Wegge, Alina Hermann, Nina Schubert, Anna Splanemann, Joachim Zettler
  • Polymeric hGH prodrugs
    Patent number: 12133883
    Abstract: The present invention relates to a polymeric human growth hormone prodrug and dry, liquid and reconstituted pharmaceutical formulation comprising said prodrug. It furthermore relates to their use as medicaments for the treatment of diseases which can be treated with growth hormone and to methods of treatment. It also relates to methods of application of such polymeric human growth hormone prodrug or pharmaceutical formulation.
    Type: Grant
    Filed: August 28, 2020
    Date of Patent: November 5, 2024
    Assignee: Ascendis Pharma Endocrinology Division A/S
    Inventors: Thomas Kurpiers, Harald Rau, Evelyn Exner, Steen Jensen, Grethe Nørskov Rasmussen, Torben Lessmann, Thomas Wegge, Alina Hermann, Nina Schubert, Anna Splanemann, Joachim Zettler
  • COMPOSITION COMPRISING A FLUOROPHORE LABELLED UPAR-TARGETING PEPTIDE CONJUGATE
    Publication number: 20230117827
    Abstract: The present invention describes a composition comprising a fluorophore labelled uPAR-targeting component, a buffer and a surfactant, wherein the fluorophore labelled uPAR-targeting component is solubilized in the composition by means of the surfactant being present, and wherein the composition comprises a maximum of 10 wt % water, preferably a maximum of 5 wt % water.
    Type: Application
    Filed: January 15, 2021
    Publication date: April 20, 2023
    Applicant: FLUOGUIDE A/S
    Inventors: Grethe Nørskov Rasmussen, Andreas Kjær, Morten Albrechtsen, Line Hartvig
  • uPAR targeting peptide for use in peroperative optical imaging of invasive cancer
    Publication number: 20210138090
    Abstract: There is provided a novel conjugate that binds to the cell surface receptor uPA (uPAR). The conjugate is based on a fluorescence-labeled peptide useful as a diagnostic probe to the surfaces of cells expressing uPAR. The conjugate is capable of carrying a suitable detectable and imageable label that will allow qualitative detection and also quantitation of uPAR levels in vitro and in vivo. This renders the surgical resection of tumors more optimal.
    Type: Application
    Filed: January 15, 2021
    Publication date: May 13, 2021
    Applicant: FLUOGUIDE A/S
    Inventors: Andreas KJAER, Morten PERSSON, Karina JUHL, Sorel KURBEGOVIC, Michael PLOUG, Knud Jørgen JENSEN, Kasper Kildegaard SØRENSEN, Anders CHRISTENSEN, Line HARTVIG, Grethe Nørskov RASMUSSEN, Morten ALBRECHTSEN
  • Novel Polymeric hGH Prodrugs
    Publication number: 20200390864
    Abstract: The present invention relates to a polymeric human growth hormone prodrug and dry, liquid and reconstituted pharmaceutical formulation comprising said prodrug. It furthermore relates to their use as medicaments for the treatment of diseases which can be treated with growth hormone and to methods of treatment. It also relates to methods of application of such polymeric human growth hormone prodrug or pharmaceutical formulation.
    Type: Application
    Filed: August 28, 2020
    Publication date: December 17, 2020
    Applicant: Ascendis Pharma Endocrinology Division A/S
    Inventors: Thomas Kurpiers, Harald Rau, Evelyn Exner, Steen Jensen, Grethe Nørskov Rasmussen, Torben Lessmann, Thomas Wegge, Alina Hermann, Nina Schubert, Anna Splanemann, Joachim Zettler
  • Polymeric hGH prodrugs
    Patent number: 10799563
    Abstract: The present invention relates to a polymeric human growth hormone prodrug and dry, liquid and reconstituted pharmaceutical formulations comprising said prodrug. It furthermore relates to their use as medicaments for the treatment of diseases which can be treated with growth hormone and to methods of treatment. It also relates to methods of application of such polymeric human growth hormone prodrug or pharmaceutical formulation.
    Type: Grant
    Filed: November 17, 2015
    Date of Patent: October 13, 2020
    Assignee: Ascendis Pharma Endocrinology Division
    Inventors: Thomas Kurpiers, Harald Rau, Evelyn Exner, Steen Jensen, Grethe Nørskov Rasmussen, Torben Lessmann, Thomas Wegge, Alina Hermann, Nina Schubert, Anna Splanemann, Joachim Zettler
  • Dry Growth Hormone Composition Transiently Linked to a Polymer Carrier
    Publication number: 20200261544
    Abstract: The present invention relates to dry compositions of rhGH polymer prodrug containing a lyoprotectant and, optionally, one or more than one excipient. Such compositions are stable for at least 1 year, when stored at 2-8° C. The invention further relates to methods of manufacturing said compositions, containers comprising such composition as well as a kit of parts.
    Type: Application
    Filed: May 5, 2020
    Publication date: August 20, 2020
    Applicant: Ascendis Pharma Endocrinology Division A/S
    Inventors: Grethe Nørskov Rasmussen, Susanne Kindermann, Harald Rau, Thomas Wegge
  • Dry growth hormone composition transiently linked to a polymer carrier
    Patent number: 10682395
    Abstract: The present invention relates to dry compositions of rhGH polymer prodrug containing a lyoprotectant and, optionally, one or more than one excipient. Such compositions are stable for at least 1 year, when stored at 2-8° C. The invention further relates to methods of manufacturing said compositions, containers comprising such composition as well as a kit of parts.
    Type: Grant
    Filed: February 21, 2018
    Date of Patent: June 16, 2020
    Assignee: Ascendis Pharma Endocrinology Division A/S
    Inventors: Grethe Nørskov Rasmussen, Susanne Kindermann, Harald Rau, Thomas Wegge
  • Dry Growth Hormone Composition Transiently Linked to a Polymer Carrier
    Publication number: 20180185452
    Abstract: The present invention relates to dry compositions of rhGH polymer prodrug containing a lyoprotectant and, optionally, one or more than one excipient. Such compositions are stable for at least 1 year, when stored at 2-8° C. The invention further relates to methods of manufacturing said compositions, containers comprising such composition as well as a kit of parts.
    Type: Application
    Filed: February 21, 2018
    Publication date: July 5, 2018
    Applicant: Ascendis Pharma Endocrinology Division A/S
    Inventors: Grethe Nørskov Rasmussen, Susanne Kindermann, Harald Rau, Thomas Wegge
  • Dry growth hormone composition transiently linked to a polymer carrier
    Patent number: 9919033
    Abstract: The present invention relates to dry compositions of rhGH polymer prodrug containing a lyoprotectant and, optionally, one or more than one excipient. Such compositions are stable for at least 1 year, when stored at 2-8° C. The invention further relates to methods of manufacturing said compositions, containers comprising such composition as well as a kit of parts.
    Type: Grant
    Filed: November 1, 2016
    Date of Patent: March 20, 2018
    Assignee: Ascendis Pharma Endocrinology Division A/S
    Inventors: Grethe Nørskov Rasmussen, Susanne Kindermann, Harald Rau, Thomas Wegge
  • Novel Polymeric hGH Prodrugs
    Publication number: 20170354716
    Abstract: The present invention relates to a polymeric human growth hormone prodrug and dry, liquid and reconstituted pharmaceutical formulations comprising said prodrug. It furthermore relates to their use as medicaments for the treatment of diseases which can be treated with growth hormone and to methods of treatment. It also relates to methods of application of such polymeric human growth hormone prodrug or pharmaceutical formulation.
    Type: Application
    Filed: November 17, 2015
    Publication date: December 14, 2017
    Applicant: Ascendis Pharma Endocrinology Division A/S
    Inventors: Thomas Kurpiers, Harald Rau, Evelyn Exner, Steen Jensen, Grethe Nørskov Rasmussen, Torben Lessmann, Thomas Wegge, Alina Hermann, Nina Schubert, Anna Splanemann, Joachim Zettler
  • Dry Growth Hormone Composition Transiently Linked to a Polymer Carrier
    Publication number: 20170056477
    Abstract: The present invention relates to dry compositions of rhGH polymer prodrug containing a lyoprotectant and, optionally, one or more than one excipient. Such compositions are stable for at least 1 year, when stored at 2-8° C. The invention further relates to methods of manufacturing said compositions, containers comprising such composition as well as a kit of parts.
    Type: Application
    Filed: November 1, 2016
    Publication date: March 2, 2017
    Applicant: Ascendis Pharma Growth Disorders Division A/S
    Inventors: Grethe Nørskov Rasmussen, Susanne Kindermann, Harald Rau, Thomas Wegge
  • Dry growth hormone composition transiently linked to a polymer carrier
    Patent number: 9511122
    Abstract: The present invention relates to dry compositions of rhGH polymer prodrug containing a lyoprotectant and, optionally, one or more than one excipient. Such compositions are stable for at least 1 year, when stored at 2-8° C. The invention further relates to methods of manufacturing said compositions, containers comprising such composition as well as a kit of parts.
    Type: Grant
    Filed: December 15, 2010
    Date of Patent: December 6, 2016
    Assignee: Ascendis Pharma Growth Disorders Division A/S
    Inventors: Grethe Nørskov Rasmussen, Susanne Kindermann, Harald Rau, Thomas Wegge
  • DRY GROWTH HORMONE COMPOSITION TRANSIENTLY LINKED TO A POLYMER CARRIER
    Publication number: 20120322721
    Abstract: The present invention relates to dry compositions of rhGH polymer prodrug containing a lyoprotectant and, optionally, one or more than one excipient. Such compositions are stable for at least 1 year, when stored at 2-8° C. The invention further relates to methods of manufacturing said compositions, containers comprising such composition as well as a kit of parts.
    Type: Application
    Filed: December 15, 2010
    Publication date: December 20, 2012
    Inventors: Grethe Nørskov Rasmussen, Susanne Kindermann, Harald Rau, Thomas Wegge