Patents by Inventor Grzegorz Wojciechowski

Grzegorz Wojciechowski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240060075
    Abstract: Provided herein are compositions and methods for producing myrcene by culturing genetically modified microbial host cells that express a myrcene synthase and optionally a geranyl pyroplosphate synthase. Also provided herein are isolated nucleic acid molecules that encode myrcene synthase variants derived from the Ocimum species myrcene synthase, which comprise one or more amino acid substitutions that improve in vivo performance of myrcene synthase in genetically modified microbial host cells. Also provided herein are isolated myrcene synthase variants that exhibit an improved activity for converting geranyl diphosphate into myrcene.
    Type: Application
    Filed: August 23, 2023
    Publication date: February 22, 2024
    Inventors: Andrew MAIN, Grzegorz WOJCIECHOWSKI, Yue YANG, Lishan ZHAO
  • Patent number: 11767533
    Abstract: Provided herein are compositions and methods for producing myrcene by culturing genetically modified microbial host cells that express a myrcene synthase and optionally a geranyl pyroplosphate synthase. Also provided herein are isolated nucleic acid molecules that encode myrcene synthase variants derived from the Ocimum species myrcene synthase, which comprise one or more amino acid substitutions that improve in vivo performance of myrcene synthase in genetically modified microbial host cells. Also provided herein are isolated myrcene synthase variants that exhibit an improved activity for converting geranyl diphosphate into myrcene.
    Type: Grant
    Filed: July 9, 2021
    Date of Patent: September 26, 2023
    Assignee: AMYRIS, INC.
    Inventors: Andrew Main, Grzegorz Wojciechowski, Yue Yang, Lishan Zhao
  • Publication number: 20220002735
    Abstract: Provided herein are compositions and methods for producing myrcene by culturing genetically modified microbial host cells that express a myrcene synthase and optionally a geranyl pyroplosphate synthase. Also provided herein are isolated nucleic acid molecules that encode myrcene synthase variants derived from the Ocimum species myrcene synthase, which comprise one or more amino acid substitutions that improve in vivo performance of myrcene synthase in genetically modified microbial host cells. Also provided herein are isolated myrcene synthase variants that exhibit an improved activity for converting geranyl diphosphate into myrcene.
    Type: Application
    Filed: July 9, 2021
    Publication date: January 6, 2022
    Inventors: Andrew MAIN, Grzegorz WOJCIECHOWSKI, Yue YANG, Lishan ZHAO
  • Patent number: 11085046
    Abstract: Provided herein are compositions and methods for producing myrcene by culturing genetically modified microbial host cells that express a myrcene synthase and optionally a geranyl pyrophosphate synthase. Also provided herein are isolated nucleic acid molecules that encode myrcene synthase variants derived from the Ocimum species myrcene synthase, which comprise one or more amino acid substitutions that improve in vivo performance of myrcene synthase in genetically modified microbial host cells. Also provided herein are isolated myrcene synthase variants that exhibit an improved activity for converting geranyl diphosphate into myrcene.
    Type: Grant
    Filed: October 28, 2016
    Date of Patent: August 10, 2021
    Assignee: AMYRIS, INC.
    Inventors: Andrew Main, Grzegorz Wojciechowski, Yue Yang, Lishan Zhao
  • Publication number: 20190382773
    Abstract: Provided herein are compositions and methods for producing myrcene by culturing genetically modified microbial host cells that express a myrcene synthase and optionally a geranyl pyrophosphate synthase. Also provided herein are isolated nude is acid molecules that encode myrcene synthase variants derived from the Ocimum species myrcene synthase, which comprise one or more amino acid substitutions that improve in vivo performance of myrcene synthase in genetically modified microbial host cells. Also provided herein are isolated myrcene synthase variants that exhibit an improved activity for converting geranyl diphosphate into myrcene.
    Type: Application
    Filed: October 28, 2016
    Publication date: December 19, 2019
    Inventors: Andrew MAIN, Grzegorz WOJCIECHOWSKI, Yue YANG, Lishan ZHAO
  • Patent number: 9248550
    Abstract: Abrasive articles including a body having a first abrasive layer, a second abrasive layer and one or more reinforcing layers for use with cordless tools have a reduced thickness with respect to conventional counterparts. Techniques for producing and using such abrasive articles are described. In one embodiment, the first abrasive layer and the second abrasive layer comprise abrasive particles in a bond material. In an embodiment, a reinforcing layer is disposed between the first abrasive layer and the second abrasive layer. In a particular embodiment, the body comprises an average thickness of not greater than about 5 mm. In another particular embodiment, the abrasive particles can comprise silicon carbide.
    Type: Grant
    Filed: March 1, 2013
    Date of Patent: February 2, 2016
    Assignees: Saint-Gobain Abrasives, Inc., Saint-Gobain Abrasifs
    Inventors: Taeke Meerveld, Alessandro R. Milani, Marko W Versteegen, Grzegorz Wojciechowski, Karolina Rozanska-Zaworska
  • Patent number: 9080163
    Abstract: The invention relates to recombinant expression of variant forms of C1 CBH1a and homologs thereof, having improved thermostability, low-pH tolerance, specific activity and other desirable properties. Also provided are methods for producing ethanol and other valuable organic compounds by combining cellobiohydrolase variants with cellulosic materials.
    Type: Grant
    Filed: May 9, 2014
    Date of Patent: July 14, 2015
    Assignee: Codexis, Inc.
    Inventors: Vesna Mitchell, Grzegorz Wojciechowski, Oscar Alvizo
  • Publication number: 20140322796
    Abstract: The invention relates to recombinant expression of variant forms of C1 CBH1a and homologs thereof, having improved thermostability, low-pH tolerance, specific activity and other desirable properties. Also provided are methods for producing ethanol and other valuable organic compounds by combining cellobiohydrolase variants with cellulosic materials.
    Type: Application
    Filed: May 9, 2014
    Publication date: October 30, 2014
    Applicant: Codexis, Inc.
    Inventors: Vesna Mitchell, Grzegorz Wojciechowski, Oscar Alvizo
  • Patent number: 8759064
    Abstract: The invention relates to recombinant expression of variant forms of C1 CBH1a and homologs thereof, having improved thermostability, low-pH tolerance, specific activity and other desirable properties. Also provided are methods for producing ethanol and other valuable organic compounds by combining cellobiohydrolase variants with cellulosic materials.
    Type: Grant
    Filed: May 13, 2011
    Date of Patent: June 24, 2014
    Assignee: Codexis, Inc.
    Inventors: Vesna Mitchell, Grzegorz Wojciechowski, Oscar Alvizo
  • Publication number: 20130244542
    Abstract: Abrasive articles including a body having a first abrasive layer, a second abrasive layer and one or more reinforcing layers for use with cordless tools have a reduced thickness with respect to conventional counterparts. Techniques for producing and using such abrasive articles are described. In one embodiment, the first abrasive layer and the second abrasive layer comprise abrasive particles in a bond material. In an embodiment, a reinforcing layer is disposed between the first abrasive layer and the second abrasive layer. In a particular embodiment, the body comprises an average thickness of not greater than about 5 mm. In another particular embodiment, the abrasive particles can comprise silicon carbide.
    Type: Application
    Filed: March 1, 2013
    Publication date: September 19, 2013
    Inventors: Taeke Meerveld, Alessandro R. Milani, Marko W. Versteegen, Grzegorz Wojciechowski, Karolina Rozanska-Zaworska
  • Publication number: 20120003703
    Abstract: The invention relates to recombinant expression of variant forms of C1 CBH1a and homologs thereof, having improved thermostability, low-pH tolerance, specific activity and other desirable properties. Also provided are methods for producing ethanol and other valuable organic compounds by combining cellobiohydrolase variants with cellulosic materials.
    Type: Application
    Filed: May 13, 2011
    Publication date: January 5, 2012
    Applicant: Codexis, Inc.
    Inventors: Vesna Mitchell, Grzegorz Wojciechowski, Oscar Alvizo