Patents by Inventor Guan-Ming KE

Guan-Ming KE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nucleic acid-based adjuvant and porcine vaccine composition including the same
    Patent number: 10117929
    Abstract: The present invention relates to a nucleic acid-based adjuvant and a porcine vaccine composition including the same. The nucleic acid-based adjuvant, which is a nucleic acid fragment consisting of a sequence listing as SEQ ID NO: 1, can be used as the nucleic acid-based adjuvant of a vaccine composition, thereby elevating the protective ability of the porcine vaccine composition.
    Type: Grant
    Filed: November 23, 2017
    Date of Patent: November 6, 2018
    Assignee: National Pingtung University of Science and Technology
    Inventors: Hso-Chi Chaung, Guan-Ming Ke, Mei-Li Wu
  • Recombinant fusion antigen gene, recombinant fusion antigen protein and subunit vaccine composition having the same against infection of porcine reproductive and respiratory syndrome virus
    Patent number: 9441015
    Abstract: The present invention is directed to a recombinant fusion antigen gene, a recombinant fusion antigen protein and a subunit vaccine composition having the same against infection of porcine reproductive and respiratory syndrome virus (PRRSV). A recombinant fusion antigen gene, which encodes glycoprotein GP5 with truncated N?-terminal decoy epitope, a linker sequence and membrane protein M, followed by codon optimization, is expressed by a baculovirus expression system in vitro, thereby enhancing a yield of the recombinant fusion antigen protein. The recombinant fusion antigen protein can be applied in a subunit vaccine composition, for providing vaccinated animals with better protection ability without the risks of virulent spread and virulent recovery.
    Type: Grant
    Filed: March 25, 2015
    Date of Patent: September 13, 2016
    Assignee: NATIONAL PINGTUNG UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Mei-Li Wu, Hso-Chi Chaung, Guan-Ming Ke
  • RECOMBINANT FUSION ANTIGEN GENE, RECOMBINANT FUSION ANTIGEN PROTEIN AND SUBUNIT VACCINE COMPOSITION HAVING THE SAME AGAINST INFECTION OF PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS
    Publication number: 20160137699
    Abstract: The present invention is directed to a recombinant fusion antigen gene, a recombinant fusion antigen protein and a subunit vaccine composition having the same against infection of porcine reproductive and respiratory syndrome virus (PRRSV). A recombinant fusion antigen gene, which encodes glycoprotein GP5 with truncated N?-terminal decoy epitope, a linker sequence and membrane protein M, followed by codon optimization, is expressed by a baculovirus expression system in vitro, thereby enhancing a yield of the recombinant fusion antigen protein. The recombinant fusion antigen protein can be applied in a subunit vaccine composition, for providing vaccinated animals with better protection ability without the risks of virulent spread and virulent recovery.
    Type: Application
    Filed: March 25, 2015
    Publication date: May 19, 2016
    Inventors: Mei-Li WU, Hso-Chi CHAUNG, Guan-Ming KE